Could High-Dose vitamin D3 shield pregnant women from preeclampsia?

NCT ID NCT07648706

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two different doses of vitamin D3 supplements in pregnant women who have low vitamin D levels. The goal is to see if a higher dose (50,000 IU every two weeks) is better than a lower dose (5,000 IU weekly) at preventing preeclampsia, a serious pregnancy complication involving high blood pressure. The trial enrolls women with a single baby, between 8 and 18 weeks of pregnancy, and follows them through delivery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vitamin D3

What this could lead to

If successful, this could show that higher vitamin D3 doses during pregnancy reduce the risk of preeclampsia, a dangerous condition for both mother and baby.

What could go wrong

This is a relatively small, single-hospital study, so results may not apply to all populations. The optimal dose and safety of high-dose vitamin D3 in pregnancy are still being explored.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

vitamin D deficiency preeclampsia prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Faculty of Medicine and Health Sciences, Sana'a University

    RECRUITING

    Sanaa, Maeen District, Yemen

    Contact Phone: •••-•••-•••• Email: •••••@•••••