Vitamin d may cut risk of repeat preeclampsia in High-Risk pregnancies

NCT ID NCT07717931

Completed Prevention Sponsor: CMH Multan Institute of Medical Sciences Source: ClinicalTrials.gov ↗

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This study tests whether taking a daily vitamin D supplement (4000 IU) can lower the chance of preeclampsia returning in pregnant women who have had it before. Researchers will randomly assign 146 women to receive either vitamin D or a placebo from enrollment until 36 weeks of pregnancy. Participants attend check-ups every two weeks for blood pressure monitoring and have vitamin D levels measured monthly to watch for toxicity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Vitamin D (cholecalciferol) 4000 IU taken orally once daily
What this could lead to: If effective, daily vitamin D could become a simple, low-cost way to prevent preeclampsia in women who have had it before.
What could go wrong: This is a single-center trial with 146 participants, so results may not apply to all populations. Vitamin D can be toxic at high doses, and the benefit over placebo is unproven.

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Conditions

The condition(s) this trial relates to.

hypertension, pregnancy-induced preeclampsia prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PREECLAMPSIA

Contacts and locations

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Locations

CMH Multan Institute of Medical Sciences

Multan, Punjab Province, 60000, Pakistan

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