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Which drug best steadies blood pressure during C-Section in preeclampsia?

NCT ID NCT07795710

Disease control Sponsor: Minia University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time

Summary

This trial tests three medications, phenylephrine, norepinephrine, and ephedrine, to see which one best manages low blood pressure that can occur after spinal anesthesia in women with preeclampsia having a cesarean delivery. Researchers will give each participant one of the three drugs as needed and track heart rate and blood pressure changes. The goal is to find the safest and most effective option for this specific group of patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Three blood pressure medications: phenylephrine, norepinephrine, and ephedrine
What this could lead to
If one drug works best, it could guide safer blood pressure management during cesarean delivery for women with preeclampsia.
What could go wrong
The trial is small and early, and results may not apply to all patients. Each drug carries risks like heart rate changes or blood pressure swings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

150 people

The number who actually took part.

Started

Jan 2024

Finished

Jan 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 40 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Preeclamptic pregnant female * ASA II and III * singleton or twin pregnancies will be scheduled for caesarean delivery * diagnosis of preeclampsia as a new onset of hypertension and proteinuria. Exclusion Criteria: * chronic hypertension, labor or failed trial of labor, * body mass index ≥40 kg/m2 , * resting heart rate \<60 bpm, eclampsia, * known fetal anomalies, contraindications to spinal anesthesia, abruption placentae, and cord prolapas.

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Conditions

The condition(s) this trial relates to.

preeclampsia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ephedrine Norepinephrine

Contacts and locations

Locations

  • Minia University

    Minya, Egypt

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