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Can a neck ultrasound predict fluid balance in preeclampsia?

NCT ID NCT07786246

Knowledge-focused Sponsor: Tanta University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now This study
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Cancelled before anyone took part.

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Approved
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When the status isn't known

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First seen Aug 25, 2026 · Last updated Aug 26, 2026 · Updated 1 time

Summary

This study investigates whether an ultrasound measurement of the internal jugular vein in the neck can help assess fluid status in pregnant women with preeclampsia, compared to those with normal blood pressure. Researchers will measure the vein's collapsibility index before cesarean section to see if it correlates with preeclampsia severity and predicts the risk of low blood pressure after spinal anesthesia. The goal is to find a simple, non-invasive way to guide fluid management in this high-risk group.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could provide a simple ultrasound method to assess fluid status in preeclampsia, potentially improving management and reducing complications.
What could go wrong
This is an observational study, so it cannot prove cause and effect. The findings may not apply to all patients or settings, and the ultrasound technique requires skill to perform accurately.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients admitted at obstetric theater in Tanta University Hospital

Ages

18 to 40 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Singleton parturients from 18 to 40 years old. 2. Either normotensive or preeclamptic parturients scheduled for elective cesarean section under neuro-axial block matched for gestational age 28-40 weeks will be included: 3. Normotensive group: uncomplicated normotensive pregnancy with systolic blood pressure below 140 mmHg and diastolic blood pressure below 90mmHg without proteinuria. 4. Preeclamptic Group: new onset preeclamptic pregnant female with gestational hypertension after 20 weeks of pregnancy diagnosed based on ISSHP Guidelines: systolic blood pressure ≥140 mmHg and/or a diastolic blood pressure ≥90 mmHg, accompanied by one or more of the following: * Proteinuria (≥300 mg in a 24-hour urine sample) * Alb/Cr ratio ≥30 mg/mmol, * Organ dysfunction (renal insufficiency (creatinine level\>1.1mg%), liver involvement (liver enzyme levels ≥3 times normal), neurological complications (Headache and blurring of vision) and hematological involvement (thrombocytopenia\<100.000)). Exclusion Criteria: 1. Parturients with pre-existing cardiac \& vascular disease affecting blood volume and vascular compliance: (Valvular or congenital heart disease, arrhythmia, previous history of venous thromboembolism, chronic kidney disease, gestational diabetes). 2. multiple gestations 3. known thyroid disorders or chronic hypertension 4. patients with BMI \>40 and patients requiring emergency delivery.

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Conditions

The condition(s) this trial relates to.

preeclampsia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pre-eclampsia Preeclampsia

How to take part

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  1. The places running it

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  2. The official record

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Contacts and locations

Locations

  • Tanta University Hospital

    RECRUITING

    Tanta, El-Gharbia Govenorate, 31527, Egypt

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