Tanta University

This study tests whether cilostazol, a drug used for blood flow, can reduce fat buildup and scarring risk in the liver. About 50 adults with fatty liver disease (not caused by alcohol) will take the drug or a placebo. The goal is to see if the drug improves ultrasound images and …

This study tests two different acid-reducing medicines (P-CAB and PPI) as part of a four-drug treatment for H. pylori, a stomach infection. About 320 adults who have not been treated before will take one of the two combinations. The goal is to see which approach kills the bacteri…

This study compares using tissue from the mouth (oral mucosa) versus tissue from the labia (labial graft) to repair a narrowed urethra in women. About 40 women with non-traumatic urethral stricture will take part. The main goal is to see which graft leads to better urine flow aft…

This study tests whether the drug erdosteine can help people with nonalcoholic fatty liver disease (NAFLD). Researchers will measure changes in liver fat and scarring in 50 adults over the course of the trial. The goal is to see if erdosteine is safe and effective for controlling…

This study tests whether vinpocetine, a drug that may improve blood flow in the brain, can safely reduce Parkinson's symptoms like tremor and stiffness. Researchers will enroll 60 adults aged 50 and older who already take levodopa for Parkinson's. The main goal is to see if the d…

This study tests if eggshell powder works as well as standard materials (Biodentine, MTA) for treating deep cavities in baby teeth. Thirty children will receive one of the treatments, and researchers will check for pain, swelling, and bone health over time. The goal is to find a …

This study tests whether silymarin, a natural antioxidant found in milk thistle, can protect brain cells and help manage symptoms in people with Parkinson's disease. Fifty adults aged 45 to 65 who are already on standard Parkinson's medication will take silymarin alongside their …

This study tests if dapagliflozin, a drug used for diabetes, can prevent heart damage caused by the chemotherapy drug doxorubicin in breast cancer patients. About 46 adults with early-stage breast cancer who have not had chemo before will take dapagliflozin or a placebo during th…

This study tests whether the drug cabergoline can prevent ovarian hyperstimulation syndrome (OHSS), a serious complication of fertility treatments. About 150 women at high risk for OHSS will receive either cabergoline or standard care (coasting). The goal is to see if cabergoline…

This study tests whether pentoxifylline, a drug already used for other conditions, can reduce inflammation in people with rheumatoid arthritis (RA). Researchers will give it to 50 adults with active RA who are already on standard medications. The main goal is to see if it improve…

This study looks at whether levothyroxine, a thyroid hormone medication, can improve heart function in children with subclinical hypothyroidism (a mild form of underactive thyroid). Researchers will measure heart pumping ability in 40 children aged 4 to 15 before and after treatm…

This study tests if carbocisteine, a drug already used for coughs, can safely reduce fat buildup in the liver for people with nonalcoholic fatty liver disease (NAFLD). About 46 adults with fatty liver will take the drug, and doctors will measure changes using ultrasound. The goal…

This study tests whether celecoxib, an anti-inflammatory drug, can improve symptoms in people with Parkinson's disease. Researchers believe brain inflammation plays a role in Parkinson's, and celecoxib may help control it. The trial will enroll 80 adults and measure changes in mo…

This study tests whether adding the deworming drug mebendazole to standard mesalamine treatment can safely improve symptoms in people with mild-to-moderate ulcerative colitis. Researchers will measure changes in disease activity, blood markers, and symptom scores over time. The t…

This study tests whether metformin, a standard diabetes drug, can safely improve movement and quality of life in people with Parkinson's disease. Researchers will give metformin or a placebo to 60 adults aged 50 and older who already take levodopa/carbidopa. The goal is to see if…

This study tests whether nicorandil, a heart medication, can reduce inflammation and improve symptoms in people with active rheumatoid arthritis. About 46 adults who are already taking standard arthritis drugs will receive nicorandil or a placebo for 3 months. Researchers will me…

This study tests a newer acid-blocking drug (vonoprazan) against a standard one, each combined with vitamin D or probiotics, to treat H. pylori infection. About 66 adults with confirmed H. pylori will receive one of three treatments for two weeks. The goal is to see which combina…

This study tests whether the drug duloxetine can prevent pancreatitis, a painful complication that sometimes happens after a procedure called ERCP (used to diagnose and treat bile duct problems). The trial will enroll 44 adults with biliary disease who are scheduled for ERCP. Hal…

This study tests whether ondansetron, a drug often used for nausea, can prevent pancreatitis after a procedure called ERCP. Pancreatitis is a common and serious complication of ERCP. The trial will enroll 44 adults and compare those who get ondansetron to those who do not, checki…

This study compares two ways of giving ondansetron (a lozenge you dissolve in your mouth versus an injection into a vein) to prevent shivering in women having a cesarean section. About 90 women will take part. The goal is to find out which method works better and is more comforta…

This study compares two types of pain blocks (Quadro-Iliac Plane Block and Erector Spinae Plane Block) given after total hip replacement. The goal is to see which one delays the need for extra pain medicine and reduces total morphine use. About 76 adults having hip replacement un…

This study tests whether injecting botulinum toxin-A (like Botox) into the bladder can help children under 18 who have trouble urinating or wet the bed at night and haven't improved with standard treatments. The goal is to see if it improves symptoms and to check for side effects…

This study looks at whether giving ondansetron (an anti-nausea drug) through a vein or near the nerves around the stomach works better to reduce pain and vomiting after laparoscopic sleeve gastrectomy. About 482 adults having this weight-loss surgery will take part. The goal is t…

This study tests three different medicines (empagliflozin, acetazolamide, and metolazone) given alongside standard water pills to people hospitalized with acute heart failure and fluid buildup. The goal is to see which one helps the body remove more fluid over three days. The stu…

This study tests whether fexofenadine, a common allergy medication, can improve quality of life for people with Parkinson's disease who are already on standard treatment. Researchers will enroll 46 adults aged 50 and older with mild to moderate Parkinson's. The goal is to see if …

This study tests whether melatonin (a natural sleep hormone) works as well as pregabalin (a nerve pain medication) for reducing pain and anxiety after spine surgery. About 105 adults undergoing planned spine surgery will receive one of the two medicines right after the operation.…

This study tests whether adding roflumilast, a drug used for other conditions, to standard antidepressants can better reduce depression symptoms. About 60 adults with major depression and high symptom scores will take the combination for 8 weeks. The main goal is to see if depres…

This study tests whether giving calcitonin early after a spinal cord injury can lower the chance or severity of nerve pain. About 126 adults with recent spinal cord injuries will receive either calcitonin or a placebo, and their pain levels will be tracked for up to a year. The g…

This study tests whether fenofibrate, a medicine usually used for high cholesterol, can reduce nerve damage (peripheral neuropathy) caused by a common chemotherapy combination for multiple myeloma. About 44 newly diagnosed patients will receive either standard chemo alone or chem…

This study tests two different numbing injections to see which one controls pain better after hypospadias repair in boys aged 1 to 5. One injection targets the sacral area near the spine, the other targets the caudal space. Researchers will measure pain levels, need for extra pai…

This study tests whether dapagliflozin, a medicine usually used for diabetes, can help reduce symptoms of major depression. About 60 adults with depression who have not improved enough with standard treatments will take the drug for a set period. The main goal is to see if their …

This study compares three common drugs—theophylline, sumatriptan, and gabapentin—to see which works best for treating post-dural puncture headache, a severe headache that can occur after a spinal tap or epidural. Researchers will enroll 75 adults aged 21 to 50 who have this type …

This study tests two different numbing injections (nerve blocks) to see which one controls pain better after open-heart surgery. About 66 adults having heart surgery will receive one of the two blocks. The goal is to reduce the need for strong painkillers (opioids) and improve re…

This study tests whether an ondansetron lozenge works as well as an IV version to prevent shivering in children having their tonsils removed. About 210 children aged 4 to 15 will take part. The goal is to find a simpler, less invasive way to reduce post-surgery shivering.

This study tests whether giving children oral melatonin or a nebulized drug called dexmedetomidine before tonsil surgery can reduce confusion and agitation when they wake up. It involves 96 children aged 3 to 7. The goal is to find a better way to keep kids calm and comfortable a…

This study tests if adding empagliflozin, a diabetes drug, can reduce weight gain and other metabolic problems caused by olanzapine in people with schizophrenia. About 40 adults aged 18-60 who take olanzapine will receive either empagliflozin or a placebo. The main goal is to see…

This study looks at whether a specific ultrasound-guided nerve block can lower the body's stress response and improve pain control in adults having umbilical hernia repair. About 100 participants will be randomly assigned to receive either the nerve block or standard care. The ma…

This study compares standard bladder training with and without biofeedback for children who have trouble emptying their bladder properly. About 124 children under 18 with dysfunctional voiding will participate. The goal is to see if adding biofeedback—a technique that uses sensor…

This study tests a nerve block (MTP) against standard patient-controlled pain medication (PCA) in 40 adults having scoliosis surgery. The goal is to see which method provides better pain control and reduces the need for extra pain drugs. Participants will be monitored for 24 hour…

This study tests whether adding the antihistamine desloratadine to standard mesalamine therapy can reduce inflammation and disease activity in people with mild-to-moderate ulcerative colitis. About 44 adults aged 18-65 who are already taking mesalamine will receive either deslora…

This study tests two methods to reduce pain after a cesarean section: a nerve block (TFP block) and a medication given in the spinal fluid (intrathecal dexmedetomidine). Fifty women having a planned C-section will be randomly assigned to one of the two groups. The goal is to see …

This study tests whether giving a single dose of dexmedetomidine, a calming medication, at different times before surgery can lower the body's stress response when a breathing tube is placed. About 45 adults having surgery will be randomly assigned to receive the drug at differen…

This study compares three different ways to clean the bowel before a colonoscopy to see which works best and is easiest for patients. About 450 adults will be randomly assigned to one of three preparation methods. Researchers will measure how clean the bowel gets, any side effect…

This study looks at why some people with rheumatoid arthritis have trouble swallowing. Researchers will use a small camera to examine the throat and see if joint problems are the cause. About 137 adults with RA will take part to help identify early warning signs.

This study looks at two substances in the blood, endocan and copeptin, in premature babies born between 28 and 36 weeks who have breathing problems. Researchers want to see if higher levels of these markers can predict how severe the breathing condition will be. The goal is to fi…

This study looks at how a dental procedure called Deep Marginal Elevation (DME) affects the gums and bone around a tooth with a deep cavity. Researchers will collect fluid from the gums and take X-rays to check for inflammation and bone changes. The goal is to understand how DME …