Tanta University

This trial compares two microsurgical techniques—single versus double dartos flap—for repairing distal hypospadias in children. Researchers will measure which method leads to fewer complications like fistulas, meatal narrowing, or infections. The study includes 100 boys aged 6 mo…

This study tests whether nicorandil, a drug usually used for heart conditions, can reduce inflammation and improve symptoms in people with active rheumatoid arthritis. 46 participants will take nicorandil tablets for 3 months. Researchers will measure joint disease activity and p…

This study tests whether carbocisteine, a drug already used for coughs, can safely reduce fat buildup in the liver of people with nonalcoholic fatty liver disease (NAFLD). About 46 adults with fatty liver will take the drug and be monitored for changes in liver fat via ultrasound…

This phase 2 trial tests whether dapagliflozin, a drug used for diabetes, can prevent heart damage caused by the chemotherapy drug doxorubicin in breast cancer patients. Researchers will enroll 46 women with early-stage breast cancer who are about to start chemotherapy. Participa…

This study compares two methods to prevent ovarian hyperstimulation syndrome (OHSS), a serious side effect of fertility treatments. About 150 women at high risk for OHSS will receive either cabergoline or a standard 'coasting' procedure. The goal is to see which approach better r…

This study tests a newer acid-blocking drug (vonoprazan) against a standard one, each combined with vitamin D or probiotics, to treat H. pylori infection. About 66 adults with confirmed H. pylori will receive one of three treatments for two weeks. The goal is to see which combina…

This study tests whether adding mebendazole, a common deworming medication, to standard mesalamine therapy can improve symptoms in people with mild-to-moderate ulcerative colitis. 46 adults will take mebendazole or a placebo twice daily for 6 months. Researchers will measure chan…

This study tests whether adding empagliflozin, a diabetes drug, can reduce weight gain and other metabolic side effects caused by olanzapine in people with schizophrenia. Forty adults aged 18 to 60 who take olanzapine will receive either empagliflozin or a placebo for several wee…

This study looks at whether treating children with a mild form of underactive thyroid (subclinical hypothyroidism) using a medication called levothyroxine can improve how well their hearts pump blood. The researchers will measure heart function in 40 children aged 4 to 15 before …

This study is testing whether adding the allergy medicine desloratadine to standard ulcerative colitis treatment can better control inflammation and symptoms. About 44 adults with mild to moderate ulcerative colitis will take either desloratadine plus mesalamine or mesalamine alo…

This study compares eggshell powder to Biodentine for treating tooth pulp exposure in children's baby molars. Thirty kids with deep cavities but no infection will get a pulpotomy, where the damaged pulp is removed and the material is placed. Researchers will check for pain, swell…

This study tests whether vinpocetine, a drug thought to improve blood flow in the brain, can safely reduce Parkinson's symptoms like tremor and stiffness. Researchers will enroll 60 adults with Parkinson's who already take levodopa. The goal is to see if adding vinpocetine leads …

This study tests whether erdosteine, a drug usually used for lung conditions, can help people with nonalcoholic fatty liver disease. Fifty adults with fatty liver will receive either standard care (diet and exercise) or standard care plus erdosteine. Researchers will measure chan…

This early-stage trial tests whether cilostazol, a drug used for leg pain, can help people with nonalcoholic fatty liver disease (NAFLD). About 50 adults with fatty liver will take the drug to see if it reduces liver fat and lowers fibrosis risk scores. The study aims to find a n…

This study tests whether metformin, a standard diabetes medication, can safely improve movement and quality of life in people with Parkinson's disease. Researchers will enroll 60 adults aged 50 and older who are already taking levodopa/carbidopa. The main goal is to see if metfor…

This study compares two types of acid-reducing drugs—vonoprazan (a newer drug) and rabeprazole (a standard drug)—when used as part of a 10-day combination therapy for H. pylori infection. About 320 adults with confirmed H. pylori will be randomly assigned to one of the two treatm…

This Phase 2 trial is testing whether silymarin, an antioxidant from milk thistle, can protect brain cells and improve symptoms in people with Parkinson's disease. Researchers will give 50 adults either silymarin or a placebo alongside their usual Parkinson's medications. The goa…

This Phase 2 trial tests whether adding pentoxifylline (a drug usually used for blood flow) to standard methotrexate therapy can reduce inflammation in people with active rheumatoid arthritis. Fifty adults aged 18–70 with moderate-to-severe disease will receive the combination fo…

This study compares two surgical techniques for treating a narrowed urethra in women: using a graft from the mouth or from the labia. Forty women with non-traumatic urethral stricture will be randomly assigned to one of the two procedures. The main goal is to see which graft lead…

This study looks at two substances in the blood—endocan and copeptin—in 40 premature babies born between 28 and 36 weeks who have breathing trouble (respiratory distress syndrome). Researchers will measure these markers on the first day of life to see if they can predict how seve…

This study tests whether an ondansetron lozenge works as well as an IV injection to prevent shivering in women having a cesarean section. About 90 women will receive either the lozenge or the IV before surgery. The goal is to find a simpler, more comfortable way to reduce shiveri…

This study tests whether an ondansetron lozenge works as well as an IV to prevent shivering in children aged 4 to 15 having their tonsils removed. Shivering is a common side effect after anesthesia. The trial will enroll 210 children and also check for nausea, vomiting, and tempe…

This study tests whether ondansetron, a drug often used for nausea, can prevent pancreatitis (inflammation of the pancreas) after a procedure called ERCP. About 44 adults who need this procedure will receive ondansetron or a placebo. The main goal is to see if fewer people develo…

This phase 3 trial tests whether the nerve pain medication duloxetine can prevent pancreatitis, a serious complication that sometimes occurs after an ERCP procedure. Researchers will give duloxetine or a placebo to 44 adults with biliary disease before their ERCP. The main goal i…

This study compares two minimally invasive procedures—cryoneurolysis (freezing nerves) and radiofrequency (using electric pulses)—to relieve knee pain in adults with osteoarthritis who haven't responded to standard treatments like painkillers or physical therapy. Sixty participan…

This study compares two types of nerve blocks to see which provides better pain relief after total hip replacement. Fifty adults having hip surgery will receive one of the two blocks. Researchers will measure pain scores and how much extra morphine is needed. The goal is to impro…

This study tests whether injecting Botox or hyaluronic acid into the knee joint can reduce pain in people with knee osteoarthritis. Fifty adults aged 50 and older with moderate to severe knee arthritis will receive three weekly injections of one of the two treatments. The main go…

This study tests two different ultrasound-guided nerve blocks to see which provides better pain relief for children aged 6 to 12 after chest surgery. Seventy-five children will receive either a subtransverse process interligamentary plane block or a rhomboid intercostal block com…

This study compares two types of nerve blocks—Quadro-Iliac Plane Block and Erector Spinae Plane Block—for pain relief after total hip replacement. About 76 adults undergoing hip surgery will receive one of the two blocks. Researchers will measure how long pain relief lasts and ho…

This trial tests whether a short, temporary nerve stimulation can reduce pain in people with moderate to severe knee osteoarthritis. About 100 adults aged 30 to 70 who have not found relief from oral pain medications or physical therapy will receive a brief electrical pulse to sp…

This study tests whether adding shock wave therapy to standard physical rehabilitation helps people with scapular dyskinesis, a condition where the shoulder blade moves abnormally. About 100 adults who have had symptoms for at least six months will be split into two groups: one g…

This study compares three different surgical techniques for men with very large prostates (over 100 mL) who have severe urinary symptoms. Ninety men will be randomly assigned to receive either thulium fiber laser, holmium laser, or bipolar electrosurgery. Researchers will measure…

This trial tests if using ultrasound to guide a nerve root injection works as well as the standard X-ray method for treating lower back and leg pain from irritated nerves. Sixty-four adults aged 18 to 75 will receive one injection of steroid and numbing medicine, then be followed…

This study tests three pelvic floor treatments in 150 men with lifelong premature ejaculation: electromagnetic stimulation, biofeedback training, and standard exercises. The goal is to see which best increases ejaculation time and improves control. Participants will be treated fo…

This study tests whether combining two types of nerve blocks (superior hypogastric plexus block and transversus abdominis plane block) can better control pain after abdominal hysterectomy. About 44 adults undergoing this surgery will receive either the combo block or standard car…

This study tests whether giving calcitonin early after a spinal cord injury can lower the chance or severity of nerve pain. About 126 adults with a recent spinal injury will receive either calcitonin or a placebo. Researchers will track pain levels and side effects for up to a ye…

This study looks at whether giving the anti-nausea drug ondansetron near the nerves in the belly works as well as giving it through a vein to control pain and vomiting after laparoscopic sleeve gastrectomy. About 482 adults having this weight-loss surgery will take part. The goal…

This phase 3 trial tests whether adding roflumilast (a COPD drug) to the antidepressant fluoxetine helps people with major depression who haven't responded well to treatment. Sixty adults with moderate-to-severe depression will take either the combination or a placebo for 8 weeks…

This study tests whether injecting botulinum toxin-A (like Botox) into the bladder can help children with certain bladder problems that haven't improved with standard treatments. It includes children under 18 with either dysfunctional voiding (trouble peeing normally) or nighttim…

This study compares three medications—theophylline, sumatriptan, and gabapentin—to see which works best for post-dural puncture headache, a severe headache that can occur after a spinal tap or epidural. Researchers will enroll 75 adults aged 21 to 50 who have this type of headach…

This study tests which nerve block technique better controls pain after open-heart surgery. 66 adults will receive one of two ultrasound-guided injections before surgery. The goal is to reduce the need for strong painkillers (opioids) and improve comfort during recovery.

This study looks at whether adding biofeedback (a therapy that uses sensors to help children learn to control their pelvic muscles) to standard bladder training helps children with dysfunctional voiding (trouble peeing normally). About 124 children under 18 will be randomly assig…

This study tests three different drugs—empagliflozin, acetazolamide, and metolazone—added to standard water pills (loop diuretics) in 66 adults hospitalized for acute decompensated heart failure. The goal is to see which drug works best at increasing urine output over three days.…

This study is testing whether fexofenadine, a common allergy medication, can improve quality of life for people with Parkinson's disease who are already on standard treatment. Researchers will enroll 46 adults aged 50 and older with mild to moderate Parkinson's. The main goal is …

This study tests whether melatonin (a natural sleep hormone) works as well as pregabalin (a nerve pain drug) for managing pain and anxiety after spine surgery. About 105 adults aged 21-60 having elective spine surgery will receive one of the two medicines right after surgery. Res…

This study tests whether giving children oral melatonin or a nebulized drug called dexmedetomidine before surgery can reduce confusion and agitation when they wake up after adenotonsillectomy. About 96 children aged 3 to 7 will be randomly assigned to one of three groups: melaton…

This study compares three different ways to clean the bowel before a colonoscopy to see which is safest, easiest, and works best. About 450 adults will be randomly assigned to one of three preparation methods. Researchers will measure how clean the bowel gets, any side effects, a…

This study is testing whether a special nerve block, called EXORA, can reduce the body's stress response and pain during umbilical hernia surgery. One hundred adults will be randomly assigned to receive either general anesthesia alone or general anesthesia plus the EXORA block. R…

This study compares two ways to manage pain after scoliosis surgery: a nerve block called MTP (injected near the spine) versus patient-controlled morphine (PCA). Forty adults with idiopathic scoliosis will be randomly assigned to one of the two methods. The main goal is to see wh…

This study tests whether celecoxib, an anti-inflammatory drug, can help people with Parkinson's disease. Researchers believe brain inflammation plays a role in Parkinson's, and celecoxib may reduce that inflammation. The trial will include 80 adults with Parkinson's and measure c…

This study tests whether dapagliflozin, a drug normally used for diabetes, can help reduce depression symptoms when added to standard antidepressant treatment. Sixty adults with moderate to severe depression will receive either dapagliflozin plus fluoxetine or fluoxetine alone. T…

This study tests whether fenofibrate, a drug typically used for high cholesterol, can prevent or reduce nerve damage caused by a common chemotherapy regimen for multiple myeloma. The trial will enroll 44 newly diagnosed patients, half receiving fenofibrate alongside their standar…

This study compares two ways to manage pain after a C-section: a nerve block (TFP block) and a medication added to spinal anesthesia (intrathecal dexmedetomidine). Fifty women undergoing planned C-sections will be randomly assigned to one of the two methods. Researchers will meas…

This study tests whether giving dexmedetomidine 20 minutes before anesthesia, instead of 10 minutes, better controls stress responses like high blood pressure and heart rate during breathing tube insertion. 45 adults undergoing surgery will be randomly assigned to one of three ti…

This study compares two types of nerve blocks—sacral erector spinae plane block and caudal block—to see which provides better pain relief after hypospadias repair in boys aged 1 to 5. Seventy children will receive one of the two blocks along with standard care. Researchers will m…

This study looks at why people with rheumatoid arthritis (RA) may have trouble swallowing. Researchers will use a small, flexible camera to examine the throat and voice box in 137 adults with RA. They aim to find factors that predict swallowing difficulty and see if joint problem…

This study tests a dental procedure called Deep Marginal Elevation (DME) in 36 adults with deep cavities. DME uses a special cement to raise the cavity margin, making it easier to clean and restore. Researchers will check gum fluid and X-rays to see if the procedure affects gum i…