Nerve pain drug duloxetine tested to stop pancreatitis after ERCP

NCT ID NCT06860984

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests whether the nerve pain medication duloxetine can prevent pancreatitis, a serious complication that sometimes occurs after an ERCP procedure. Researchers will give duloxetine or a placebo to 44 adults with biliary disease before their ERCP. The main goal is to see if fewer people develop pancreatitis in the duloxetine group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

duloxetine

What this could lead to

If it works, this could offer a simple, non-opioid way to prevent a common and serious complication after ERCP.

What could go wrong

This is a small, early-phase trial with only 44 participants, so results may not apply to everyone. Duloxetine also has side effects like nausea and dizziness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BILIARY DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

biliary tract disorder gallbladder disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Tanta Unuversity

    RECRUITING

    Tanta, 31527, Egypt

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••