Nerve pain drug duloxetine tested to stop pancreatitis after ERCP

NCT ID NCT06860984

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests whether the nerve pain medication duloxetine can prevent pancreatitis, a serious complication that sometimes occurs after an ERCP procedure. Researchers will give duloxetine or a placebo to 44 adults with biliary disease before their ERCP. The main goal is to see if fewer people develop pancreatitis in the duloxetine group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
duloxetine
What this could lead to
If it works, this could offer a simple, non-opioid way to prevent a common and serious complication after ERCP.
What could go wrong
This is a small, early-phase trial with only 44 participants, so results may not apply to everyone. Duloxetine also has side effects like nausea and dizziness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Tanta Unuversity

    RECRUITING

    Tanta, 31527, Egypt

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