Heart drug nicorandil tested as new arthritis treatment

NCT ID NCT07516769

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether nicorandil, a drug usually used for heart conditions, can reduce inflammation and improve symptoms in people with active rheumatoid arthritis. 46 participants will take nicorandil tablets for 3 months. Researchers will measure joint disease activity and physical function to see if the drug helps.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Nicorandil (oral tablet)
What this could lead to
If it works, this could point toward a new treatment option for rheumatoid arthritis that reduces inflammation and improves daily function.
What could go wrong
This is a small early-phase trial with only 46 people, so results may not apply widely. Nicorandil is not a standard arthritis drug, and its safety and effectiveness are still unproven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for RHUMATOID ARTHISIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Tanta university

    RECRUITING

    Tanta, Gharbia Governorate, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.