Can melatonin or a nebulized drug calm kids after surgery?

NCT ID NCT07345715

Recruiting now Symptom relief Sponsor: Tanta University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving children oral melatonin or a nebulized drug called dexmedetomidine before surgery can reduce confusion and agitation when they wake up after adenotonsillectomy. About 96 children aged 3 to 7 will be randomly assigned to one of three groups: melatonin, dexmedetomidine, or a placebo. The goal is to find a safer, gentler way to help kids recover calmly.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: oral melatonin syrup or nebulized dexmedetomidine
What this could lead to: If it works, this could point toward a simple, safe way to calm children after surgery without strong sedatives.
What could go wrong: This is a small, early-phase trial with only 96 children, so results may not apply to all kids or surgeries. Neither drug is guaranteed to work better than placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Emergence Delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADENOTONSILLECTOMY CHILDREN EMERGENCE AGITATION NEBULIZED DEXMEDETOMIDINE ORAL MELATONIN

Can melatonin or a nebulized drug calm kids after surgery?

Summary

What this could mean

Get notified about this study

Conditions

As listed by the trial registrant

Contacts and locations

Locations

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