CHILDREN

This study is testing two different training approaches to help children with dysfunctional voiding, a condition that causes problems like frequent urination, urgency, and accidents. Researchers will compare standard pelvic floor muscle training alone against the same training co…

This early-stage study is testing whether a drug called blinatumomab is safe and can help children and young adults with severe, treatment-resistant lupus. Participants will receive two short courses of injections and be closely monitored for a full year. The main goal is to see …

This study is testing whether a standard thyroid medication (levothyroxine) can improve heart function in children who have a mild thyroid problem called subclinical hypothyroidism. Researchers will enroll 40 children aged 4 to 15 and measure their heart function before and after…

This study aims to see which of two special mouthwashes works better to control the germs that cause cavities in children. Researchers will compare a probiotic-based mouthwash to one containing an antimicrobial ingredient. They will measure bacteria levels, plaque buildup, and sa…

This study aims to learn about the long-term safety of a medication called finerenone when given to children and young adults (ages 1-18) who have chronic kidney disease and proteinuria. Participants will take finerenone along with their standard kidney medication for up to 18 mo…

This study is testing a specific breathing technique, called a lung volume optimization maneuver, for children in two critical situations. For kids recovering from heart surgery, it aims to see if the technique improves heart function and lung mechanics, potentially shortening th…

This study is testing whether a structured physical activity program can improve thinking skills and daily living abilities in children who have had surgery for congenital heart disease. Researchers will compare 300 children who had heart surgery with children who had other surge…

This study is testing whether a treatment called rectal ozone therapy can help protect the brain and reduce long-term problems in children who have suffered a serious brain injury. It will involve 120 children, aged 1 month to 18 years, who are in intensive care with injuries fro…

This study is testing if a special solution called taurolidine can prevent infections in the catheters used by children and young adults with cancer. Researchers will compare it to a standard saline solution to see which one better stops germs from growing inside the catheter. Th…

This study is testing a special high-flow nasal oxygen device to prevent dangerously low oxygen levels in children while they are being put to sleep for surgery. Researchers will compare this method to standard care in 48 healthy children aged 2-10 years. The goal is to find the …

This study is testing if giving tuberculosis (TB) preventive medicine immediately after a household member is diagnosed can stop children and teenagers from catching the infection. Researchers will compare kids who get the medicine right away to those who follow standard care, wh…

This study aims to see if a special educational cartoon can help reduce anxiety in children aged 7 to 12 before they have elective surgery. Researchers will compare the cartoon's effect to a regular fun cartoon and to standard verbal information given by hospital staff. The goal …

This study is testing whether high-dose omega-3 fatty acid supplements can help reduce symptoms of attention deficit hyperactivity disorder (ADHD) in children and adolescents who have low omega-3 levels. Over 12 weeks, 100 participants will be randomly assigned to receive either …

This study aims to find the better option for preventing agitation and distress when children wake up from tonsil and adenoid removal surgery. Researchers will compare a melatonin pill with a misted medication called dexmedetomidine, given before anesthesia. The trial involves 96…

This study aims to see which type of exercise is better for improving balance and stability in children with Down syndrome. It will compare two 8-week programs: one using cognitive-motor training (like games and dancing) and one using Pilates exercises. The study will include 32 …

This study aims to find the best dose of a two-drug nasal spray to safely calm young children (ages 1-6) before they go into surgery. Researchers want to see how quickly the spray works, how well it helps during procedures like getting an IV, and if it helps children wake up more…

This study is testing whether acupuncture can help children with ADHD. It will compare two groups of kids aged 6-12: one receiving acupuncture plus Chinese herbal medicine, and another receiving only the herbal medicine. The goal is to see if adding acupuncture improves symptoms …

This study is looking at whether drinking milk or eating yogurt can help improve children's memory, attention, and thinking skills over a few hours. Researchers will test healthy kids aged 9-14 after they have different types of dairy (full-fat, low-fat, or fat-free) or skip a sn…

This study aims to understand the long-term health of children born to mothers who have had a solid organ transplant (like kidney, liver, or heart). Researchers want to see if these children have a higher risk of heart, kidney, or immune system problems later in life, possibly du…

This study aims to find the best way to teach CPR to schoolchildren. Researchers will compare a traditional hands-on training session with a shorter video-based lesson to see which one helps kids learn and remember the life-saving skills more effectively. The goal is to gather ev…

This study aims to see how reliable and accurate a new handheld device is for measuring leg strength in typically developing children. Researchers will test 30 kids aged 5-16, comparing the new tool's readings to a standard lab machine. The goal is to validate a simpler tool that…

This study aims to understand how the brain controls movement in children with cerebral palsy compared to healthy children. Researchers will use safe, non-invasive brain scanning techniques (NIRS and EEG) while participants perform simple tasks. The goal is to gather knowledge ab…

This study aims to understand how modern fertility treatments might affect children's long-term health. Researchers will observe 300 children in Kazakhstan, up to 3 years old, who were conceived using IVF or ICSI. They will measure growth, brain development, and reproductive heal…