CHILDREN

This study tests whether a combination of two antiviral drugs (entecavir and pegylated interferon) can achieve a functional cure for chronic hepatitis B in children aged 3 to 6 years. A functional cure means the virus is undetectable and stays that way for at least 24 weeks after…

This study tests whether giving a combination of two antiviral drugs (entecavir and pegylated interferon) can cure chronic hepatitis B in children aged 3 to 6 years. About 60 children with active virus and elevated liver enzymes will receive either one drug alone or both drugs in…

This study tests whether a special optical film on glasses can slow the growth of the eye in children aged 6-10 with mild farsightedness. 180 children will be split into two groups: one gets the special glasses, the other gets regular check-ups. The goal is to see if the glasses …

This study will see if a rapid test (SPOTFIRE) can help doctors make better treatment decisions for children with respiratory infections in the emergency department. About 720 children aged 2 months to 18 years will be randomly assigned to either get the rapid test or standard ca…

This study tests whether a 10-week camp program can help children and teens (ages 7-14) who struggle with binge eating. Some parents will also receive special training to support their child. Researchers will follow participants for up to five years to see if the program reduces …

This study explores whether a type of therapy called Compassion Focussed Therapy, combined with Loving Kindness Meditation, can help children aged 12-17 with epilepsy who feel anxious, stressed, or ashamed about their condition. Participants will attend three online therapy sessi…

This study looks at whether a digital app called LUSHA can help children aged 7-12 with ADHD and their parents. The app is designed as a game to motivate behavior change and improve parent-child interaction. Researchers will track how often families use the app over 3 months and …

This study looks at whether watching cartoons and getting foot reflexology can help children aged 4 to 6 feel less anxious, nauseous, and in pain after planned surgery. About 105 kids will be involved. The goal is to find simple, drug-free ways to improve recovery.

This study looks at whether a special breathing maneuver during heart surgery can improve heart and lung function in children with congenital heart disease. About 80 children will be randomly assigned to receive either the maneuver or standard care. The goal is to see if this app…

This study will test a tablet-based tool called TICOALA to check language understanding and learning in children aged 3 to 7 who visit a child psychiatry service in Paris. The goal is to see if children, parents, and doctors find the tool acceptable and easy to use. About 50 chil…

This study looks at whether children with hearing loss have weaker lungs and breathing muscles compared to healthy children. Researchers will measure lung function and muscle strength in 30 kids aged 7 to 16. The goal is to understand if hearing loss affects more than just hearin…

This study looks at whether taking short, 5-minute activity breaks during regular school lessons can make children enjoy physical activity more. About 810 primary school children will take part, with some classes doing these breaks every hour for 12 weeks while others continue as…

This study will track 200 children admitted to the pediatric ICU to see how abnormal levels of minerals like sodium, potassium, and calcium relate to their outcomes. The goal is to find patterns that could help doctors identify risks early and improve treatment. No new treatments…

This study looks at whether an 8-week CrossFit program can make children aged 7 to 11 fitter and happier. Thirty kids will be split into two groups: one does CrossFit twice a week, the other sticks to their normal routine. Researchers will measure strength, body fat, anxiety, str…

This study follows 93 children aged 5-18 with brain tumors to see how their nutrition changes during radiation therapy and how it relates to their quality of life. Researchers will measure weight, diet, and well-being using questionnaires. The goal is to create a nutrition plan t…