CHILDREN

This study is testing different combinations of chemotherapy drugs and local treatments for children under 6 with retinoblastoma, a rare eye cancer. The main goal is to control the cancer and save the child's eye, avoiding surgical removal or external beam radiation whenever poss…

This study is testing a new way of running a diabetes clinic for children under 10. It focuses on using play, teaching calmness during daily care tasks, promoting healthy lifestyles, and connecting families for support. The goal is to see if this more family-friendly approach imp…

This study tested whether an 8-week program of movement and thinking games could improve cognitive skills and balance in preschool children. Fifty typically developing children participated, with half receiving the special training twice weekly while the other half continued with…

This study is testing a new, detailed care plan for children recovering from heart surgery. The plan focuses on carefully balancing oxygen levels in the body during the first 8 critical hours after surgery. Researchers hope this approach will help children's hearts recover better…

This study is evaluating a community program in Rotterdam designed to help children aged 4-12 who are overweight. The program involves various local providers offering activities focused on nutrition, physical activity, and healthy habits. Researchers are measuring the program's …

This study is testing a new screening and management program for fatty liver disease (MASLD) in children. It will enroll 270 overweight children aged 7-11 to see if using a simple waist measurement is a good first step for screening. The main goal is to build and test a school- a…

This study is collecting real-world safety information about rivaroxaban, a blood-thinning medication, in children who have undergone Fontan heart surgery. Researchers are monitoring 61 pediatric patients to better understand the risks of major and minor bleeding events during tr…

This study is testing a one-year program designed to help prevent obesity in preschool children. The program involves health education, dietary guidance, and increased physical activity for children, and also works with their families and schools. Researchers are measuring childr…

This study is testing a new physical therapy approach for children aged 6-14 who have dysfunctional voiding, a condition that makes it hard to control urination. Researchers are comparing two types of guided exercise training to see which is better at helping kids empty their bla…

This study is testing two simple, non-drug methods to help children feel less pain and fear during a common nose swab test for respiratory infections. Researchers will compare using a palm massager or a stress ball against standard care in children aged 6-12. The goal is to find …

This study is testing if a simple, colorful walkway mat can make it easier for children to get moving after abdominal surgery. Researchers want to see if turning movement into a game reduces kids' pain and fear, and helps them take their first steps sooner. The study involves 74 …

This study aims to find out if a child's body position (sitting or lying down) changes the results of a special test used to diagnose constipation problems. Researchers will compare test results from 120 children, some with constipation and some without, to see which position giv…

This study aims to understand how different types of footwear affect brain activity in children while they walk. Researchers will measure brain waves in 37 healthy children aged 6-7 as they walk barefoot, in minimalist 'barefoot' shoes, and in conventional shoes. The goal is to g…

This study aims to understand how the brain reacts to pain and how virtual reality (VR) might help manage it. Researchers will use a special, safe brain scanner on 20 healthy children while they experience mild simulated pain and play different VR and iPad games. The goal is to f…

This study aimed to see if two new monitoring tools could quickly predict kidney injury in children undergoing heart surgery. It planned to test special ultrasound and a light-based sensor during surgery to measure kidney blood flow and oxygen levels. The goal was to find a faste…

This study is testing a new team-based strategy to improve how a large children's hospital screens for depression. It involves 40 doctors and staff members. The goal is to make the screening process smoother and faster so children who need help get connected to mental health serv…

This study aims to understand why some parents are hesitant to vaccinate their young children. Researchers will survey 600 parents in Turkey and use computer algorithms (machine learning) to analyze their responses. The goal is to create a tool that can predict vaccine hesitancy,…

This study aims to understand if secondhand smoke increases the risk of gum disease in children. Researchers will compare 146 healthy children, some living with smoking parents and some with non-smoking parents. They will check the children's gum health and measure specific infla…