CHILDREN

This study tested whether combining low-dose atropine eye drops with special soft contact lenses can slow the progression of high myopia (severe nearsightedness) in children aged 6-12. 120 children were split into three groups: one got the combo therapy, one got atropine alone wi…

This study tested the safety of Jivi (BAY 94-9027), a longer-lasting clotting factor, in 36 children aged 7 to 12 with severe hemophilia A. The medicine is already approved for older patients, but this trial focused on younger kids to check for allergic reactions and whether the …

This completed study collected speech samples from 931 children aged 2 to 14 to test a new diagnostic app called 'Hi Dongdong'. The app uses AI to assess articulation and pronunciation, comparing it to a standard test. The goal was to see if the app can accurately identify speech…

This study tested whether a special forehead thermometer called SpotOn can accurately measure core body temperature in children during surgery. Researchers enrolled 70 children aged 1 day to 16 years having elective surgery. The goal was to see if this non-invasive sensor could r…

This study tested a 6-month home-based program for 300 children ages 2–6 who were overweight or obese. Community health workers visited families to encourage healthy eating, physical activity, and parenting skills. The goal was to see if the program could improve children's weigh…

This study looked at two different speech therapies for children aged 6-8 who have cochlear implants. Twelve children received either perceptual training or phonetic placement therapy for 12 hours over 8 weeks. The goal was to see which therapy better improves speech clarity and …

This study tested whether teaching children aged 9-12 how to manage their time during haemodialysis can reduce their anxiety and fear. Twenty children were split into two groups: one received the training, the other got usual care. Researchers measured anxiety and fear levels bef…

This study tested whether fun, animation-based breathing exercises can improve physical and mental health in 130 school children aged 8 to 12. Kids followed guided breathing videos, and researchers measured chest expansion, cough strength, walking speed, stress levels, and attent…

This study tested three different sedatives given as a mist to children aged 3-7 before they had their tonsils and adenoids removed. The goal was to see which drug helped kids stay calm and separate easily from their parents. Sixty children were randomly assigned to receive eithe…

This study tested a program designed to help children aged 8-12 with cystic fibrosis and their mothers build life skills and psychological resilience. The program included activities like laughter yoga and aimed to improve emotional well-being, quality of life, and lung function.…

This study looked at whether two simple, low-cost tools—Buzzy® (a vibrating device) and HSTT (a quick injection technique)—can reduce pain and fear in children aged 4 to 6 during intramuscular shots in the emergency department. 120 children participated, and researchers measured …

This study tested whether using a low-frequency laser on an acupuncture point (P6) can help prevent nausea and vomiting caused by chemotherapy in children aged 2 to 20. The 30 participants received the laser treatment alongside standard anti-nausea drugs. The goal was to see if a…

This study tested a program called AWARE that helps caregivers and doctors review children's psychiatric medications and decide whether to lower or stop some of them. The goal is to reduce harm from side effects like weight gain and diabetes. 31 children aged 6-17 who were on mul…

This study looked at 60 children aged 3-12 who had inguinal hernia repair. Half received anesthesia through a computer-controlled IV pump (target-controlled infusion), and the other half breathed in sevoflurane gas. Researchers measured how stable their heart rate and blood press…

This study tested whether letting children play digital games or watch cartoons before and during stitches can lower their pain, fear, and anxiety. 90 children aged 5-10 in the ER were split into three groups: one played games, one watched cartoons, and one received standard care…

This study tested two different pain-relief methods for children aged 1 to 7 having hernia surgery. One method uses an ultrasound to guide a numbing injection near the belly muscles, while the other is a standard injection near the tailbone. The goal was to see which one keeps ch…

This study tested two non-drug methods to reduce pain, fear, and anxiety in children aged 4 to 6 getting intramuscular injections in a pediatric emergency department. One method used a flat, bumpy plastic device called ShotBlocker pressed against the skin before the shot. The oth…

This study looked at two types of ultrasound-guided pain blocks for children aged 2 to 7 having lower abdominal surgery. The goal was to see which block—erector spinae or caudal—provides better pain relief after surgery. Sixty children took part, and their pain was measured using…

This study tested whether showing children an animated film through virtual reality glasses one hour before cardiac catheterization could lower their anxiety, fear, and pain. Forty-two children aged 5 to 10 took part. The goal was to see if a fun, immersive distraction could make…

This study tested two simple distraction methods—blowing bubbles and a mental game with praise—to help children aged 7 to 12 feel less pain, fear, and anxiety during a blood draw. 207 children took part, and their pain and fear levels were measured before and after the procedure.…

This study tested whether visual or sensory distractions (like videos or toys) help reduce pain and anxiety in 100 healthy children aged 4-6 during a dental numbing shot. Kids were randomly assigned to a distraction group or a no-distraction group. Researchers measured pain and a…

This study tested whether melatonin patches can reduce dental anxiety in children aged 5-7. Fifty-two kids were split into two groups: one got melatonin patches on their forearm 30 minutes before treatment, the other got placebo stickers. Researchers measured anxiety using a chil…

This study tested whether Emla cream, a numbing cream, can reduce pain in 3-month-old babies during their first pneumococcal vaccination. 72 healthy babies were randomly given either Emla cream or a placebo cream before the shot. Pain was measured using a standard scale (FLACC) a…

This study tested a special way to give intramuscular injections to children aged 6-12. Instead of the usual method, nurses used a precise ventrogluteal technique with a 90-degree angle and quick needle insertion and removal. The 90 children were split into two groups: one got th…

This study tests whether advanced ultrasound techniques (2D and 3D speckle-tracking echocardiography) can detect early signs of heart muscle dysfunction in children aged 4 to 18 with end-stage kidney disease who have been on dialysis for at least a year. Researchers aim to see if…

This study aimed to understand the brain and genetics behind autism spectrum disorders (ASD). Researchers compared brain scans, thinking tests, and DNA from 678 people with ASD, healthy volunteers, and their parents. The goal was to find links between brain activity, behavior, an…

This study looked at the quality of life of 756 children adopted from other countries who arrived in France between 2008 and 2013. Researchers used an online survey to assess their health, behavior, and school adjustment one to seven years after arrival. The goal is to find out w…

This study looked at whether using a gas called MEOPA (laughing gas) to calm children during a lung sample procedure changes the types of bacteria found in their airways. 23 children aged 3 months to 8 years old took part. The goal was to see if the gas affects the accuracy of th…

This study tested whether a heart-rate based index (ANI) can detect pain in 17 children with cerebral palsy during injections and physical therapy. Researchers measured heart rate changes before and after painful procedures and compared them to standard pain scores. The goal was …

This study explored whether a condition called meatal stenosis (a narrow urinary opening) is linked to bedwetting in boys aged 7 to 12. Researchers treated 400 boys with both conditions using a surgical procedure called meatoplasty. The goal was to see if fixing the narrow openin…

This study looked at 3,750 children aged 1-12 to find out why placing a supraglottic airway device (a type of breathing tube) can be difficult. The goal was to identify risk factors like the doctor's experience or the child's health history. The study did not test any new treatme…

This study explored whether a parent's anxiety before their child's surgery influences the child's own anxiety and pain after the operation. Researchers measured anxiety in 81 parents and their children aged 2-6 undergoing groin surgery. The goal was to see if easing parental wor…

This completed study looked at how 1,400 children with supraventricular tachycardia (a fast heart rhythm) were treated in France. Researchers compared the use of antiarrhythmic drugs and catheter ablation to see which worked better and had fewer side effects. The goal is to help …

This study looked at how traditional games (like tag or hopscotch) and free play (unstructured playtime) affect physical fitness and social skills in 104 primary school children aged 5 to 9. Researchers measured social interaction using a standard survey and compared the two play…

Researchers created a questionnaire to measure how well children aged 8-12 with asthma understand their condition. The scale, tested in 196 children, has 19 questions and is reliable. It could help tailor education to improve asthma management.

This study tested whether two devices — a knee traction dynamometer and a non-invasive muscle sensor — can reliably measure muscle strength and activity in children with cerebral palsy. Twenty children aged 5 to 16 with mild to moderate CP took part. The goal was to see if these …

This study looked back at 761 children who had pancreatic surgery to understand why the surgery was done, what complications happened, and how many children died. The goal was to fill a gap in knowledge since large-scale data on pediatric pancreatic surgery was missing. The study…

This study tested whether a special education program helps children with type 1 diabetes learn more about their condition and feel better. 68 children and teens from one hospital in France took part. They answered questionnaires about diabetes knowledge and quality of life. The …