New hope for young hemophilia patients: jivi safety trial shows promise for fewer injections
NCT ID NCT05147662
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested the safety of Jivi (BAY 94-9027), a longer-lasting clotting factor, in 36 children aged 7 to 12 with severe hemophilia A. The medicine is already approved for older patients, but this trial focused on younger kids to check for allergic reactions and whether the drug stops working well. Participants received injections twice a week for 6 months, then could switch to a schedule with up to 5 days between doses, and were monitored for 2 years.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEMOPHILIA A are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Acibadem Adana Hastanesi, Çocuk Sagligi ve Hastaliklari, Çocuk Hematoloji-Onkoloji Bölümü
Adana, 01130, Turkey (Türkiye)
-
Akdeniz Üniversitesi Tip Fakültesi Çocuk Sagligi ve Hastaliklari Anabilim Dali Çocuk Hematoloji ve Onkoloji Bilim Dali
Antalya, 07059, Turkey (Türkiye)
-
Arnold Palmer Hospital for Children
Orlando, Florida, 32806, United States
-
Ege Üniversitesi Tip Fakültesi, Çocuk Sagligi ve Hastaliklari Anabilim Dali, Çocuk Hematoloji Bilim Dali
Izmir, 35100, Turkey (Türkiye)
-
Gaziantep Üniversitesi Tip Fakültesi, Sahinbey Arastirma Ve Uygulama Hastanesi, Çocuk Hematoloji ve Onkoloji Bilim Dali
Gaziantep, 27100, Turkey (Türkiye)
-
HEMORIO
Rio de Janeiro, Rio de Janeiro, 20211-030, Brazil
-
Hacettepe Üniversitesi Tip Fakültesi, Hacettepe Ihsan Dogramaci Çocuk Hastanesi,
Ankara, 06230, Turkey (Türkiye)
-
Hosp Clínicas Facult. Med. de Ribeirão Preto / USP
Ribeirão Preto, São Paulo, 14051-140, Brazil
-
Hospital das Clínicas de Campinas - UNICAMP
Campinas, São Paulo, 13083-878, Brazil
-
Hospital de Niños Sor María Ludovica
La Plata, Buenos Aires, 1900, Argentina
-
Instituo Hematología Arbesú
Godoy Cruz, Mendoza Province, 5501, Argentina
-
Instituto de Hematología Dr. Rubén Dávoli
Rosario, Santa Fe Province, S2000CKF, Argentina
-
Irmandadade da Santa Casa de Misericordia de Sao Paulo (iSANTACASA)
São Paulo, São Paulo, 01223-001, Brazil
-
McMaster Children's Hospital
Hamilton, Ontario, L8N 3Z5, Canada
-
OUS Rikshospitalet Klinisk Forskningspost Barn
Oslo, 372, Norway
-
Ondokuz Mayis Üniversitesi Tip Fakültesi, Saglik Uygulama ve Arastirma Merkezi, Çocuk Sagligi ve Hastaliklari Anabilim Dali
Samsun, 55200, Turkey (Türkiye)
-
Ospedale Pediatrico Bambino Gesù - Oncoematologia, Trapianto Emopoietico e Terapie Cellulari
Roma (RM), Lazio, 00165, Italy