Bayer

This study aims to monitor the long-term safety of the heart failure drug vericiguat in 1,400 Japanese patients over two years. Researchers will track side effects and compare how well the drug prevents heart-related deaths versus standard treatments. The study is observational, …

This study is checking the safety of darolutamide, a prostate cancer drug, when given alongside standard hormone therapy to men in India. It focuses on men whose prostate cancer hasn't spread but keeps growing despite low testosterone levels. Researchers will monitor for side eff…

This is the first study in people to test a new drug, BAY 3547926, for advanced liver cancer (hepatocellular carcinoma). The drug works by delivering a tiny amount of radiation directly to cancer cells to try to shrink tumors. The main goals are to find a safe dose and see how we…

This study monitors the safety of vericiguat, an approved heart failure medication, in routine Korean medical practice. Researchers will track 1,350 patients with chronic heart failure for up to 12 months to identify any side effects and see how well the drug works in real-world …

This study is testing whether adding a new oral medicine called finerenone to standard kidney care helps children with chronic kidney disease. Researchers want to see if the combination reduces protein leaking into urine better than standard care alone. About 219 children, aged 6…

This study aims to learn about the long-term safety of a medication called finerenone when given to children and young adults (ages 1-18) who have chronic kidney disease and proteinuria. Participants will take finerenone along with their standard kidney medication for up to 18 mo…

This study allows cancer patients who were already receiving darolutamide in a previous Bayer-sponsored trial and are benefiting from it to continue treatment. It aims to provide continued access to the medication while closely monitoring for any side effects or safety issues. Ab…

This study is monitoring the safety of darolutamide, an already approved prostate cancer medication, in 600 Korean patients. Researchers will track side effects and see how well the drug works over time by reviewing patients' medical records during their regular doctor visits. Th…

This study aims to find a better treatment for women with a non-cancerous thickening of the uterine lining, a condition that can lead to cancer if untreated. Researchers are comparing a hormonal IUD (Mirena) inserted once to a daily hormone pill taken for six months to see which …

This early-stage clinical trial is testing a new cancer drug called BAY 3713372 in people with advanced solid tumors that have a specific genetic change called MTAP deletion. Researchers want to find the safest dose, understand how the body processes the drug, and see if it can s…

This early-stage study is testing whether adding an experimental drug called BAY3498264 to an existing cancer drug (sotorasib) can work better against advanced solid tumors with a specific KRAS mutation. Researchers want to find the safest dose of this combination and see if it h…

This study is collecting information on how well the cancer drug larotrectinib works and what side effects patients experience when it's used in real-world medical care. It will follow about 100 adults and children whose cancer has an NTRK gene fusion and has spread or returned. …

This study is observing Japanese men with prostate cancer that has spread to a few bones. It aims to learn more about the safety and effectiveness of a three-drug combination treatment they are already receiving from their doctors. Researchers will review medical records to see h…

This is the first study in people testing a new drug called 225Ac-PSMA-Trillium for advanced prostate cancer that has spread and no longer responds to standard hormone treatments. The drug is designed to deliver radiation directly to prostate cancer cells. Researchers will find t…

This study is collecting information on how safe and effective Eylea eye injections are for Japanese babies with retinopathy of prematurity (ROP), an eye condition that affects premature infants. Researchers will follow 75 babies who are already receiving Eylea treatment as part …

This program provides access to an investigational oral drug called sevabertinib for adults with advanced non-small cell lung cancer that has a specific genetic mutation (HER2). It's designed for people whose cancer has progressed after at least one prior treatment and who have n…

This study is testing whether a new drug called finerenone can help children with heart failure when added to their usual treatments. Researchers will give the drug or a placebo to about 111 children aged 6 months to 18 years for 3 months to see if it improves heart function and …

This is an early-stage study to check the safety of a new drug called BAY 3389934 in healthy Japanese volunteers. The drug is being developed to treat a dangerous blood clotting problem that can happen during severe infections (sepsis). Researchers will give the drug at different…

This study is testing whether a new oral pill (BAY 2927088) works better and is safer than standard intravenous chemotherapy for people with advanced non-small cell lung cancer that has a specific genetic change called a HER2 mutation. About 278 adults who have not yet received t…

This study monitors the safety of an already-approved hemophilia A treatment called Jivi (damoctocog alfa pegol) in Korean patients. Researchers will collect real-world data from about 20 patients who are already receiving this medication as part of their regular care. The goal i…

This study is testing an oral pill called BAY2927088 for people with advanced solid tumors that have a specific genetic change (HER2 mutation). The goal is to see if the pill can shrink tumors and control the cancer's growth. About 111 adults with cancers like colorectal, breast,…

This study is observing how well the eye injection medication Eylea works and what side effects occur when used in regular medical practice for neovascular glaucoma. Doctors will follow 480 patients in Japan for 6 months after they start treatment. The goal is to understand the r…

This study aims to learn more about how well the approved drug larotrectinib (VITRAKVI) works and how safe it is during routine use for patients with advanced solid tumors caused by a specific genetic change called an NTRK gene fusion. Researchers will observe about 150 adults an…

This study is looking at how well an over-the-counter chewable tablet called Talcid works to relieve heartburn and other stomach symptoms. These symptoms can flare up when people stop taking certain long-term prescription acid-reducing medications (PPIs). About 167 adults in Germ…

This study aims to understand which treatments work best for advanced liver cancer after patients have received initial immunotherapy combinations. Researchers will collect data from 300 adults who have already started their next treatment as part of their regular care. The study…

This study aims to understand how a recently approved medication called acoramidis works for patients with ATTR amyloidosis cardiomyopathy in real-world settings, outside of controlled clinical trials. Researchers will observe up to 2,000 adults across Europe who are starting thi…

This study aims to test how reliable a new method is for measuring the kidney's 'reserve' capacity—how much extra work it can do when needed. Researchers will enroll 50 adults, including both healthy people and those with stable kidney problems. Participants will drink a protein …

This study aims to learn more about how Parkinson's disease changes over time in people who still experience movement problems like tremors and stiffness even while taking their standard medications. Researchers will observe 300 participants for up to 5 years, collecting informat…

This study aims to understand why some people develop kidney problems after heart surgery. Researchers will collect blood and urine samples from 200 patients before and after their scheduled operations to look for biological markers linked to kidney injury. The goal is to gather …

This study aims to understand how the kidney-protecting drug finerenone is actually used by doctors and patients in South Korea. Researchers will observe and collect information from about 500 adults with chronic kidney disease and type 2 diabetes who are starting this already-ap…

This is an observational follow-up study for women who previously took part in a clinical trial for a menopause hot flash treatment called elizanetant. Researchers are not testing a new treatment. Instead, they are collecting information through surveys and medical records to lea…

This study aims to count how many premature babies in the UK with a serious eye condition (retinopathy of prematurity) are being treated with Eylea injections using a special pediatric dosing device. Researchers will use existing hospital records to gather this information, with …

This study is collecting information about people with chronic kidney disease and type 2 diabetes who are already taking the medication finerenone as part of their regular care. Researchers will look at existing health records from 50,000 people in the US and Asia to understand w…

This study is collecting real-world safety information on finerenone, an approved heart failure medication, as it is used in routine medical practice in South Korea. Researchers will follow 300 adults with chronic heart failure for one year to monitor for any side effects and see…

This study aims to understand how doctors use the drug darolutamide in real-world clinics to treat men with metastatic prostate cancer that has spread at diagnosis. Researchers will look back at the medical records of about 1,400 men to see who gets the drug, how they take it, an…