Scientists probe kidney damage after heart surgery to find clues for prevention

NCT ID NCT06772025

Recruiting now Knowledge-focused Sponsor: Bayer Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study is observing 200 adults scheduled for heart surgery to understand why some develop acute kidney injury afterward. Researchers will collect blood and urine samples before and after surgery to measure biomarkers linked to kidney damage. No experimental treatments are given—participants receive standard care. The goal is to uncover mechanisms that could lead to future prevention strategies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help identify early warning signs and potential targets for future treatments to prevent kidney injury after heart surgery.
What could go wrong: This is an observational study with no treatment being tested, so it will not directly help participants. Results may not lead to new therapies for years, if at all.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute kidney injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC SURGERY ASSOCIATED - ACUTE KIDNEY INJURY

Contacts and locations

Locations

Guy's and St Thomas' NHS Foundation Trust | Guy's & St Thomas' Hospital - Department of Critical Care & Nephrology
RECRUITING

London, Greater London, SE1 7EH, United Kingdom
Guy's and St Thomas' NHS Foundation Trust | Harefield Hospital - Cardiology
NOT_YET_RECRUITING

Harefield, Greater London, UB9 6JH, United Kingdom
Herz- und Diabeteszentrum Nordrhein-Westfalen
RECRUITING

Bad Oeynhausen, North Rhine-Westphalia, 32545, Germany
Royal Papworth Hospital NHS Foundation Trust | Royal Papworth Hospital - Cardiac Surgery
RECRUITING

Cambridge, Cambridgeshire, CB2 0AY, United Kingdom

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