Can a simple gas during heart surgery protect your kidneys?
NCT ID NCT07544147
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving inhaled nitric oxide during heart surgery can prevent acute kidney injury (AKI) in high-risk patients. AKI is a common and serious complication after heart surgery with no approved prevention. The trial will include 330 adults undergoing elective heart surgery with a heart-lung machine. Participants will receive either nitric oxide gas or a placebo through their breathing circuit during surgery, and kidney function will be monitored for 90 days after.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Inhaled nitric oxide
What this could lead to
If it works, this could provide a simple, drug-free way to prevent kidney damage after heart surgery, reducing hospital stays and long-term complications.
What could go wrong
This is an early-stage trial with no prior proof of effectiveness. The treatment is only given during surgery, and results may not apply to all patients or surgeries.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Zhongshan Hospital, Fudan University
Shanghai, Shanghai Municipality, 200032, China
Contact Phone: •••-•••-•••• Email: •••••@•••••