Bayer

This study tested whether a higher dose (8 mg) of the drug aflibercept, given every 16 weeks, works as well as the standard dose (2 mg) given every 8 weeks for Chinese patients with diabetic macular edema (DME), a diabetes-related eye condition that causes vision problems. About …

This study looked at data from 500 people in Germany with chronic heart failure who were prescribed vericiguat. Researchers wanted to see how well the drug works in real life, not just in a controlled trial. They measured deaths and hospital stays related to heart failure. The go…

This study followed 18 adults with pulmonary arterial hypertension (PAH) who had already taken riociguat in earlier trials. Researchers wanted to see if the drug remained safe and tolerable over a longer period. The goal was to keep providing treatment until it was no longer help…

This study tested the drug larotrectinib in 215 adults with various solid cancers that have a specific change in the NTRK gene. The drug works by blocking the faulty gene's signals that make cancer grow. The main goal was to see how many patients had their tumors shrink or disapp…

This study tested a higher dose (8 mg) of the drug aflibercept, given as an eye injection, for people with macular edema (swelling) caused by a blocked vein in the retina. The goal was to see if the higher dose works as well as or better than the standard 2 mg dose, while possibl…

This study tested whether adding darolutamide to standard hormone therapy (ADT) helps men with prostate cancer that has spread to other parts of the body. 669 men participated, and the goal was to see if the combination delayed cancer growth or death. Results showed improvement i…

This study tested whether adding darolutamide to standard hormone therapy and chemotherapy helps men with metastatic prostate cancer that still responds to hormones. Over 1,300 men took part. The goal was to see if the combination improved overall survival. Results showed that da…

This study tested a drug called Radium-223 in 921 men with advanced prostate cancer that no longer responds to hormone therapy and has spread to the bones. The goal was to see if it could help them live longer and slow down the disease. Participants received either the drug or a …

This study tested a new drug, BAY 3018250, to see if it can safely dissolve blood clots in people with deep vein thrombosis (DVT) in the leg. About 258 adults with recent DVT symptoms received either a high or low dose of the drug or a placebo. Researchers measured clot changes u…

This study looked at the safety of BAY 94-9027 (Jivi) in 36 children aged 7 to 12 with severe hemophilia A. The medicine is a longer-lasting clotting factor given as an injection to prevent and treat bleeding. Researchers monitored for allergic reactions and whether the drug stop…

This study tested whether the drug finerenone can slow kidney damage in people with type 1 diabetes and chronic kidney disease. About 241 adults took either finerenone or a placebo pill for 6 months, along with their usual treatments. Researchers measured changes in urine protein…

This study tested whether adding the drug copanlisib to standard rituximab therapy helps people with relapsed indolent B-cell non-Hodgkin's lymphoma live longer without their cancer getting worse. About 458 adults who had already received at least one prior treatment took part. T…

This study tested a new contrast agent called gadoquatrane for MRI scans of the body (excluding the brain and spine). The goal was to see if it works as well as current agents while using a lower dose of gadolinium. 404 adults with known or suspected health issues received both t…

This study tested a new daily pill, asundexian, to see if it can prevent another stroke in people who recently had a stroke or mini-stroke caused by a blood clot from outside the heart. Over 12,000 adults took either asundexian or a placebo alongside their usual antiplatelet medi…

This study looked at 1500 women who chose to take different vitamin supplements before or during pregnancy. Researchers tracked pregnancy progress and complications like anemia, preeclampsia, and low birth weight. The goal was to gather more data on how vitamins help in countries…

This study tested a new drug called elinzanetant to see if it helps women with sleep problems caused by menopause. About 110 women took either the drug or a placebo for 12 weeks. Researchers measured how much time they spent awake at night using sleep tests.

This study tested a drug called elinzanetant to see if it can reduce hot flashes in women who have gone through menopause. Hot flashes are common and can disrupt daily life. The drug works by blocking a protein that may trigger hot flashes. 396 women took either the drug or a pla…

This study tested a tablet that sticks to the gum to treat cold sores (herpes labialis) in adults who get them often. About 2,020 people used either the active tablet or a placebo at the first sign of a cold sore. The goal was to see if the tablet helps sores heal faster and redu…

This study looked at whether people with chronic heart failure can safely start taking vericiguat at a 5 mg dose instead of the usual 2.5 mg. The goal is to reach the full 10 mg target dose more quickly. 106 participants took the 5 mg dose for 2 weeks, and researchers monitored s…

This study tested a drug called elinzanetant for treating hot flashes in 628 women who have gone through menopause. The drug works by blocking a protein that may trigger hot flashes. Participants took either the drug or a placebo daily for 52 weeks and recorded their hot flashes …

This study looked at data from 348 people with type 2 diabetes in Germany who use the myTherapy app. The goal was to see how many have elevated levels of albumin in their urine, which is an early sign of kidney disease. Researchers tracked these levels over about a year to unders…

This study looked at sleep problems and hot flashes in 750 menopausal women aged 40-65. Researchers collected data from health records, questionnaires, and smartwatches over 28 days to understand how these issues affect quality of life and how women are currently treated. The goa…

This study looked at past medical records of 121 people with metastatic colorectal cancer (advanced bowel cancer) in Europe. Researchers wanted to see how the order of taking two approved drug combinations—regorafenib and TAS (with or without bevacizumab)—affected treatment lengt…

This study examined 150 adults with sepsis in the ICU to find blood markers that signal when a dangerous clotting problem called DIC develops. Researchers collected blood samples and hospital data over up to 56 days. No new treatments were given—only standard care. The goal was t…

This study looks at medical records of children under 18 in Japan who were prescribed rivaroxaban or warfarin for blood clots. Researchers want to see how often serious bleeding happens with each drug in everyday care. No extra tests or visits are needed—only existing health data…

This study observed over 6,500 Chinese adults with chronic kidney disease and type 2 diabetes who started taking the drug finerenone. Researchers looked at patient health records to understand how the drug is used in real life, including its effects on kidney function and potassi…

This study followed up on 100 babies who were treated for retinopathy of prematurity (ROP) in an earlier study. The goal was to see how their eyes and vision were doing over the long term. No new treatments were given; the study only observed and measured outcomes.

This study looked at the medical records of 818 adults with advanced colorectal cancer that had spread to other parts of the body. Researchers wanted to see if the order in which patients took two approved drugs—regorafenib and TAS-102 (sometimes with bevacizumab)—affected their …

This study looked at health insurance records of over 640,000 people in the US who had acute respiratory distress syndrome (ARDS) and were treated in the ICU. Researchers wanted to find out what new health problems—physical, mental, or emotional—people face after leaving the ICU,…