Indian study confirms safety of eye injection for Diabetes-Related vision loss

NCT ID NCT05511038

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 23 times

Summary

This study tested the safety of aflibercept, an already-approved eye injection, in 100 Indian adults with diabetic macular edema (DME) — a condition where diabetes damages the retina and blurs vision. Participants received injections into the eye every 4 weeks for 5 months, then every 8 weeks for a total of 48 weeks. The main goal was to track any side effects, with vision and retinal thickness also measured.

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Contacts and locations

Locations

  • Disha Eye Hospitals

    Kolkata, West Bengal, 700120, India

  • Dr. R.P. Centre for Ophthalmic Sciences, AIIMS

    New Delhi, National Capital Territory of Delhi, 110029, India

  • L.V. Prasad Eye Institute

    Hyderabad, Andhra Pradesh, 500034, India

  • Lotus Eye Hospital and Institute

    Coimbatore, Tamil Nadu, 641014, India

  • M & J Western Regional Institute of Ophthalmology

    Ahmedabad, Gujarat, 380016, India

  • Medical Research Foundation, Sankara Nethralaya

    Chennai, Tamil Nadu, 600006, India

  • Narayana Nethralaya

    Bengaluru, Karnataka, 560010, India

  • Post Graduate Institute of Medical Education and Research

    Chandigarh, 160012, India

  • Raghudeep Eye Hospital

    Ahmedabad, Gujarat, 380052, India

  • Sankara Eye Hospital

    Bengaluru, Karnataka, 560037, India

Conditions

Explore the condition pages connected to this study.