Aflibercept safety checked in indian DME patients

NCT ID NCT05511038

Completed Disease control Sponsor: Bayer Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested the safety of aflibercept, an already-approved eye injection, in 100 Indian adults with diabetic macular edema (DME). Participants received injections every 4 weeks for 5 months, then every 8 weeks for a total of 48 weeks. The main goal was to track any side effects, with additional checks on vision and eye thickness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: aflibercept (Eylea)
What this could lead to: If successful, this trial could confirm that aflibercept is safe for Indian patients with diabetic macular edema, supporting its continued use.
What could go wrong: This is a small, completed safety study, not designed to prove effectiveness. Results may not apply to all patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

diabetic macular edema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETIC MACULAR EDEMA

Contacts and locations

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Locations

Disha Eye Hospitals

Kolkata, West Bengal, 700120, India
Dr. R.P. Centre for Ophthalmic Sciences, AIIMS

New Delhi, National Capital Territory of Delhi, 110029, India
L.V. Prasad Eye Institute

Hyderabad, Andhra Pradesh, 500034, India
Lotus Eye Hospital and Institute

Coimbatore, Tamil Nadu, 641014, India
M & J Western Regional Institute of Ophthalmology

Ahmedabad, Gujarat, 380016, India
Medical Research Foundation, Sankara Nethralaya

Chennai, Tamil Nadu, 600006, India
Narayana Nethralaya

Bengaluru, Karnataka, 560010, India
Post Graduate Institute of Medical Education and Research

Chandigarh, 160012, India
Raghudeep Eye Hospital

Ahmedabad, Gujarat, 380052, India
Sankara Eye Hospital

Bengaluru, Karnataka, 560037, India

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