Can a new eye injection preserve vision in south asians with diabetes?

NCT ID NCT07753616

First seen Aug 07, 2026 ยท Last updated Aug 07, 2026

Summary

This trial tests whether faricimab, an eye injection, can improve vision and reduce swelling in South Asian patients with diabetic macular edema (DMO), a complication of diabetes that can lead to blindness. Previous studies mostly included Caucasian or East Asian participants, leaving a gap for South Asians who have higher rates of diabetes and DMO. The study will follow 120 UK-based South Asian adults for up to 88 weeks, using a treat-and-extend approach where the time between injections is adjusted based on response. The goal is to see if faricimab provides meaningful vision gains, durable control of retinal swelling, and a safe profile in this specific population.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Faricimab (intravitreal anti-VEGF injection)
What this could lead to
If successful, this could confirm faricimab as an effective treatment for diabetic macular edema in South Asian patients, potentially leading to better vision outcomes and longer-lasting effects with fewer injections.
What could go wrong
This is a phase 4 study with a relatively small sample size (120 participants), and results may not generalize to all South Asian populations. As with any eye injection, there are risks of infection, inflammation, or increased eye pressure.

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Conditions

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