New eye injection aims to reduce treatment burden for diabetic macular edema

NCT ID NCT04772105

Completed Disease control Sponsor: Bio-Thera Solutions Source: ClinicalTrials.gov ↗

First seen Jul 10, 2026 · Last updated Jul 15, 2026 · Updated 2 times

Summary

This trial tests an investigational drug called BAT5906, given as an eye injection, for people with diabetic macular edema—a condition where fluid builds up in the retina and blurs vision. The study compares two doses (2.5 mg and 4 mg) given multiple times to see which works best and lasts longer. The goal is to find a dose that controls swelling and improves eyesight while possibly allowing fewer injections over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: BAT5906 injection
What this could lead to: If successful, this treatment could help people with diabetic macular edema maintain better vision with fewer eye injections.
What could go wrong: This is an early-phase trial with only 60 participants, so results may not apply to everyone. Possible side effects include eye inflammation or vision changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

diabetic macular edema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETIC MACULAR EDEMA

Contacts and locations

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Locations

Affiliated Hospital of Nantong University

Nantong, China
Affiliated Hospital of Qingdao University

Qingdao, China
Eye Hospital of China Academy of Chinese Medical Sciences

Beijing, China
Henan Provincial Eye Hospital

Henan, China
Jiangsu Provincial Hospital of Traditional Chinese Medicine

Nanjing, China
Jieyang People's Hospital

Jieyang, China
Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong

Shantou, China
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences

Beijiang, Beijing Municipality, 100730, China
Peking University First Hospital

Beijing, China
Sun Yat-sen Memorial Hospital, Sun Yat-sen University

Guangzhou, China
The Affiliated Eye Hospital of Nanchang University

Nanchang, China
The First Affiliated Hospital of Bengbu Medical College

Bengbu, China
The First Affiliated Hospital of Zhengzhou University

Zhengzhou, China
The First Hospital of Jilin University

Jilin City, China
The Second Xiangya Hospital of Central South University

Xiangya, China
Wenzhou Medical University Affiliated Optometry Hospital

Wenzhou, China
West China Hospital of Sichuan University

Sichuan, China
Xiangya Hospital Central South University

Xiangya, China
Zhejiang Provincial People's Hospital

Hangzhou, China

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