Could fewer eye injections treat diabetic vision loss just as well?
NCT ID NCT06422507
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 28 times
Summary
This study tested whether a higher dose (8 mg) of the drug aflibercept, given every 16 weeks, works as well as the standard dose (2 mg) given every 8 weeks for Chinese patients with diabetic macular edema (DME), a diabetes-related eye condition that causes vision problems. About 333 participants received injections into the eye and were followed for about 63 weeks. The goal was to see if the higher dose could reduce the number of injections needed while maintaining similar vision improvement and safety.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Affiliated hospital of Nantong university
Nantong, Jiangsu, 226006, China
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Aier Eye Hospital (LIAONING)
Shenyang, Liaoning, China
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Beijing Aier Intech Eye Hospital
Beijing, 100000, China
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Beijing Friendship Hospital, Capital Medical University
Beijing, 100050, China
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Beijing Hospital
Beijing, Beijing Municipality, 100730, China
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Capital Medical University (CMU) - Beijing Tongren Hospital
Beijing, 100062, China
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Central South University - The Second Xiangya Hospital
Changsha, 410007, China
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Chengdu Aier Ophthalmology Hospital
Chengdu, 610041, China
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Chengdu University of Traditional Chinese Medicine - Teaching Hospital (Sichuan Province Traditional Chinese Medicine Hospital)
Chengdu, 610072, China
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Eye & Ent Hospital of Fudan University
Shanghai, 200126, China
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Eye Hospital of Wenzhou Medical University
Wenzhou, 325027, China
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Eye hospital of Shandong First Medical University
Jinan, 250299, China
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Grantham Hospital
Hong Kong, Hong Kong SAR, 00000, Hong Kong
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Guangdong Provincial Hospital of TCM
Guangzhou, Guangdong, 510120, China
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Guangzhou Aier Ophthalmology Hospital
Guangzhou, 510288, China
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Guangzhou First People Hospital
Guangzhou, Guangdong, 510180, China
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Hebei eye hospital
Hebei, 050010, China
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Henan Provincial Eye Hospital
Henan, 450008, China
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Jinan Second People's Hospital
Jinan, 250021, China
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Joint Shantou International Eye Center (JSIEC)Shantou University & the Chinese University of Hong Kong
Shantou, 515041, China
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Lanzhou University Second Hospital
Lanzhou, Gansu, 730030, China
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Luoyang Third People's Hospital
Luoyang, Henan, 471002, China
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Nanjing First Hospital
Nanjing, Jiangsu, 210006, China
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People's Hospital of Ningxia Hui Autonomous Region - Opthalmology
Ningxia, 750002, China
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Renmin Hosp., Wuhan Univ.
Wuhan, Hubei, 430040, China
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Shandong University of Traditional Chinese Medicine Affiliated Ophthalmology Hospital
Shandong, 250299, China
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Shanghai General Hospital
Shanghai, 200080, China
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Shanghai Jiao Tong University School of Medicine (SJTUSM) - XinHua Hospital
Shanghai, 200092, China
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Shanghai eye disease prevention and control center
Shanghai, 200041, China
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Shanxi Bethune Hospital
Taiyuan, Shanxi, 030032, China
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Shanxi Eye Hospital
Shanxi, 030002, China
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Shenyang He Eye Specialist Hospital
Shenyang, 110034, China
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Shijiazhuang People's Hospital
Shijiazhuang, 050011, China
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Sichuan University West China Hospital
Chengdu, Sichuan, MISSING, China
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Taizhou Hospital of Zhejiang Province
Taizhou, Zhejiang, 317099, China
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The First Affiliated Hospital of Chongqing Medical Universit
Chongqing, 400042, China
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The First Affiliated Hospital of Harbin Medical University
Harbin, Heilongjiang, 150001, China
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The First Affiliated Hospital of NanChang University
Nanchang, Jiangxi, 330006, China
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The First Hospital of Jilin University
Changchun, Jilin, 130061, China
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The Fourth People's Hospital of Shenyang
Shenyang, 110082, China
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The People's Hospital of Guangxi Zhuang Autonomous Region
Nanning, Guangxi, 530021, China
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The Second Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, 330200, China
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The Second Hospital of Anhui medical university
Hefei, Anhui, 230601, China
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The Second Hospital of Jilin University
Changchun, Jilin, 130000, China
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Tianjin Medical University Eye Hospital
Tianjin, 300384, China
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Tseung Kwan O Hospital
Tseung Kwan O, New Territories, 00000, Hong Kong
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Weifang Ophthalmology Hospital
Shandong, 261041, China
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Xi'an People's Hospital (Xi'an Fourth Hospital)
Xi'an, 710005, China
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Xianyang First People's Hospital
Xianyang, 712099, China
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Zhejiang University School of Medicine - The Second Affiliated Hospital
Hangzhou, 310003, China
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Zhengzhou Second People's Hospital
Erqi, Zhengzhou, 450015, China
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Zhujiang Hospital of Southern Medical University
Guangzhou, Guangdong, 510280, China
Conditions
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