Bayer

This study looks at how well darolutamide (Nubeqa) plus standard hormone therapy works in Chinese men whose prostate cancer has become resistant to earlier treatment but hasn't spread. About 800 men will take part, and researchers will track PSA levels to see if the cancer is con…

This observational study will follow 40 children aged 7 to 12 with hemophilia A who are already prescribed damoctocog alfa pegol (Jivi) to prevent bleeding. Researchers will collect data from routine care, including bleeding episodes and treatment patterns, over two years. The go…

This early-stage study tests whether it is safe to take nitroglycerin spray (used for chest pain) together with an experimental drug called nurandociguat (designed to help kidneys) in 36 adults with stable coronary artery disease. Both drugs widen blood vessels, so the main conce…

This study looks at the safety and effectiveness of Octocog alfa, a lab-made clotting factor, when used to treat sudden bleeding episodes in adults with severe hemophilia A. About 33 people in India who have used factor VIII before will take part. Researchers will track side effe…

This study tests a single injection of AB-1005 gene therapy directly into the brain for Japanese adults with moderate Parkinson's disease. The goal is to see if it is safe and can improve daily movement. Eight participants will be followed for 18 months.

This study follows 1,500 women in the U.S. who are starting elinzanetant, a new hormone-free medicine for hot flashes and night sweats during menopause. Researchers will track how well it works, how safe it is, and how it affects sleep and quality of life using phone surveys and …

This study tests an experimental medicine called BAY 3670549 in 360 adults with atrial fibrillation (an irregular heartbeat). Participants receive a single IV dose of the drug or a placebo to see if it can restore normal heart rhythm without needing an electrical shock procedure.…

This observational study will collect data from health records of 850 children under 2 years old who have venous thromboembolism (blood clots). The goal is to see how doctors prescribe rivaroxaban (Xarelto) and other standard blood thinners, and to track any serious bleeding. No …

This study follows 50 pregnant women with Chagas disease who take or have taken nifurtimox, to see if the drug causes harm to the baby or mother. Researchers will track birth defects, pregnancy outcomes, and infant health up to 12 months old. The goal is to collect safety data, n…

This study looks at whether a digital tool called Luscii is practical and acceptable for people with a rare heart condition called ATTR-CM. About 60 adults in Austria, Germany, and Italy will use a smartphone app and home devices to share health information with their care team. …