New drug aims to shock heart back to rhythm without electricity

NCT ID NCT07625215

Not yet recruiting Symptom relief Sponsor: Bayer Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 4 times

Summary

This study tests an experimental medicine called BAY 3670549 in 360 adults with atrial fibrillation (an irregular heartbeat). Participants receive a single IV dose of the drug or a placebo to see if it can restore normal heart rhythm without needing an electrical shock procedure. The study also checks for side effects and how the body processes the medicine.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION

Contacts and locations

Locations

AZ Delta | Clinical Trial Center - Cardiology

Roeselare, West Flanders, 8800, Belgium
American Heart of Poland S.A. - MCSN, PAKS w Chrzanowie - Oddział Intensywnej Opieki Kardiologicznej

Chrzanów, 32-500, Poland
American Heart of Poland S.A. - PAKS Centrum Kardiologii i Kardiochirurgii w Bielsku-Białej - Oddział Kardiologii

Bielsko-Biala, 43-316, Poland
Azienda Ospedaliero Universitaria Delle Marche - Clinica di Cardiologia e Aritmologia

Torrette, 60126, Italy
Azienda Ospedaliero-Universitaria Policlinico Umberto I - Malattie Cardiovascolari

Roma, 00161, Italy
Centro Cardiologico Monzino S.p.A. - UO Scompenso e Cardiologia Clinica

Milan, 20138, Italy
Duke University Hospital - Cardiology

Durham, North Carolina, 27704, United States
Ente Ecclesiastico Ospedale Generale Regionale Miulli - Cardiologia e UTIC

Acquaviva delle Fonti, 70021, Italy
Henry Ford Hospital - Cardiology

Detroit, Michigan, 48202, United States
Herz-und Diabeteszentrum NRW|Elektrophysiologie/Rhythmologie

Bad Oeynhausen, North Rhine-Westphalia, 32545, Germany
Jessa Ziekenhuis | Hartcentrum Hasselt

Hasselt, Limburg, 3500, Belgium
Klinikum Altenburger Land GmbH-Klinik für Kardiologie, Pneumologie und Internistische Intensivmedizin

Altenburg, Thuringia, 04600, Germany
Maastricht UMC

Maastricht, Limburg, 6229 HX, Netherlands
Massachusetts General Hospital - Cardiology

Boston, Massachusetts, 02114, United States
Medizinische Hochschule Hannover|Kardiologie und Angiologie

Hanover, Lower Saxony, 30625, Germany
Multiprofile Hospital for Active Treatment Dr. Stefan Cherkezov | Base 1 - Cardiology Department

Veliko Tarnovo, Veliko Tarnovo Province, 5000, Bulgaria
Multiprofile Hospital for Active Treatment Knyaginya Klementina Sofia EAD | Cardiology Department

Sofia, Sofia City Province, 1233, Bulgaria
Samodzielny Publiczny Specjalistyczny Szpital Zachodni im. sw. Jana Pawla II

Grodzisk Mazowiecki, 05 825, Poland
Semmelweis Egyetem, Varosmajori Sziv- és Ergyogyaszati Klinika

Budapest, 1122, Hungary
Tolna Vármegyei Balassa János Kórház - I. Belgyógyászati Osztály: Kardiológia, Nefrológia

Szekszárd, Tolna County, 7100, Hungary
UCHealth University of Colorado Hospital - Cardiology

Aurora, Colorado, 80045, United States
UCSF Advanced Heart Failure Comprehensive Care Center

San Francisco, California, 94143, United States
USK nr 4 w Lublinie - Kliniczny Odd. Kardiologii, Reh. Kardio., Ch. Wew. z Pododdzialem Intensywnej Opieki Kardio.

Lublin, 20-090, Poland
UZ Leuven Gasthuisberg - Cardiology diseases department

Leuven, Flemish Brabant, 3000, Belgium
Universitair Medisch Centrum Groningen

Groningen, 9713 GZ, Netherlands
University Hospital for Active Treatment Tsaritsa Joanna - ISUL | Cardiology Clinic

Sofia, Sofia City Province, 1527, Bulgaria
University Multiprofile Hospital For Active Treatment Sveti Georgi' - EAD Department of Intensive Cardiology"

Plovdiv, Plovdiv Province, 4001, Bulgaria

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