A tiny neck implant could catch Stroke-Causing clots before they reach the brain

NCT ID NCT03892824

Ongoing Prevention Sponsor: Javelin Medical Source: ClinicalTrials.gov ↗

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This trial is testing a device called the Vine™ Embolic Protection System, which is implanted in the carotid arteries to trap blood clots before they travel to the brain. It is designed for people with atrial fibrillation who are already taking blood thinners but still have a high risk of stroke. Participants receive implants in both carotid arteries and are monitored for safety and any strokes or procedure-related complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Vine™ Embolic Protection System, a device implanted in the carotid arteries to filter blood clots
What this could lead to: If it works, this could offer an extra layer of stroke protection for people with atrial fibrillation who remain at high risk despite taking blood thinners.
What could go wrong: This is an early, small study focused on safety and performance. The implant requires a procedure that carries risks, including bleeding, stroke, or complications needing surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation Embolism ischemic stroke stroke disorder prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION STROKE

Contacts and locations

Locations

Alfried-Krupp Krankenhaus Rüttenscheid

Essen, 45131, Germany
Cardio Vasculäres Centrum Frankfurt

Frankfurt, 60389, Germany
Cardioangiologisches Centrum Bethanien

Frankfurt, Germany
Carmel

Haifa, Israel
European Interbalkan Medical Center

Thessaloniki, 57001, Greece
General Hospital of Athens "Hippokrateio"

Athens, 11527, Greece
Gottsegen György Hungarian Institute of Cardiology

Budapest, Hungary
Hospital Universitario Ramon y Cajal

Madrid, Spain
Laiko Hospital

Athens, Greece
Na Homolce Hospital

Prague, Czechia
OLV Ziekenhuis

Aalst, Belgium
Poria

Tiberias, 1520800, Israel
Rabin Medical Center (RMC)

Petah Tikva, Israel
Shaari Tzedek

Jerusalem, 9103102, Israel
Szpital Kliniczny Przemienienia Pańskiego Uniwersytetu Medycznego im. Karola Marcinkowskiego w Poznaniu, Pracownia Hemodynamiki Serca

Poznan, Poland
University General Hospital of Larisa

Larissa, Greece
ZNA Stuivenberg

Antwerp, Belgium

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