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New MRI dye could make scans safer for kids

NCT ID NCT05915026

Completed Diagnosis Sponsor: Bayer Source: ClinicalTrials.gov ↗

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study tests a new contrast agent called gadoquatrane in children from birth to under 18 years old who need a contrast-enhanced MRI. The goal is to see how the drug moves through the body and check its safety. Each child gets a single injection during their MRI, and researchers take blood samples and monitor for side effects over about a week.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
gadoquatrane, a new gadolinium-based contrast agent for MRI
What this could lead to
If successful, this could lead to safer MRI scans for children using a lower dose of gadolinium.
What could go wrong
This is a Phase 3 study focused on safety and drug levels, not on how well the contrast works. It may not prove better images or fewer side effects than existing agents.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHILDREN CONTRAST ENHANCEMENT IN MAGNETIC RESONANCE IMAGING

Contacts and locations

Locations

  • Beijing Children's Hospital, Capital Medical University

    Beijing, Beijing Municipality, 100045, China

  • Centro de Diagnostico Enrique Rossi | Departamento de Investigacion Clínica

    Ciudad Autonoma de Buenos Aire, Ciudad Auton. de Buenos Aires, C1425BEE, Argentina

  • Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Pädiatrische Radiologie

    Berlin, 13353, Germany

  • Children's Mercy Hospital Kansas City - Radiology

    Kansas City, Missouri, 64108, United States

  • Clinica Universitaria Reina Fabiola | Consultorios Externos

    Córdoba, Córdoba Province, X5004FHP, Argentina

  • Fakultni nemocnice Plzen - Lochotin

    Pilsen, 32300, Czechia

  • Fakultní nemocnice Ostrava

    Ostrava - Poruba, 708 52, Czechia

  • Halo Diagnostics - Indian Wells

    Indian Wells, California, 92210, United States

  • Instytut "Pomnik - Centrum Zdrowia Dziecka"

    Warsaw, 04-730, Poland

  • Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital

    Nagoya, Aichi-ken, 453-8511, Japan

  • Jichi Medical University Hospital

    Shimotsuke, Tochigi, 329-0498, Japan

  • Juntendo University Hospital

    Bunkyo, Tokyo, 113-8431, Japan

  • Kanagawa Children's Medical Center

    Yokohama, Kanagawa, 252-8555, Japan

  • Karolinska Universitetssjukhuset Solna - Funktion Medicinsk Diagnostik, Barnradiologi

    Stockholm, Stockholm County, 171 64, Sweden

  • MUSC University Hospital - Radiology

    Charleston, South Carolina, 29425, United States

  • Multiprofile Hospital for Active Treatment Central Onco Hospital | Independent Medical Diagnostic Laboratory Mediscan

    Plovdiv, Plovdiv Province, 4002, Bulgaria

  • Nara Prefecture General Medical Center

    Nara, Nara, 630-8581, Japan

  • National Center for Child Health and Development

    Setagaya-ku, Tokyo, 157-8535, Japan

  • National Hospital Organization Nagoya Medical Center

    Nagoya, Aichi-ken, 460-0001, Japan

  • Sanatorio Allende | Departamento de Investigación Clínica

    Córdoba, Córdoba Province, X5000JHQ, Argentina

  • Shizuoka Children's Hospital

    Shizuoka, Shizuoka, 420-8660, Japan

  • The Children's Hospital Zhejiang University School of Med

    Hangzhou, Hangzhou Province, 310056, China

  • The Hospital for Sick Children (SickKids)

    Toronto, Ontario, M5G 1X8, Canada

  • Tokai University Hospital

    Isehara, Kanagawa, 259-1193, Japan

  • Tokyo Metropolitan Hospital Organization Tokyo Metropolitan Children's Medical Center

    Fuchū, Tokyo, 183-8561, Japan

  • University Hospital for Active Treatment Tsaritsa Joanna - ISUL | Radiology Department

    Sofia, 1784, Bulgaria

  • University Multiprofile Hospital for Active Treatment St. Ivan Rilski | Radiology Department

    Sofia, 1431, Bulgaria

  • University Multiprofile Hospital for Active Treatment Sveti Georgi | Base II - Radiology Department

    Plovdiv, Plovdiv Province, 4000, Bulgaria

  • Universitätsklinikum Jena - Institut für Diagnostische und Interventionelle Radiologie, Kinderradiologie

    Jena, Thuringia, 07747, Germany

  • Universitätsklinikum Leipzig - Institut für Kinderradiologie

    Leipzig, Saxony, 04103, Germany

  • Universitätsklinikum Münster - Klinik für Radiologie, Kinderradiologie

    Münster, North Rhine-Westphalia, 48149, Germany

  • Universitätsklinkum Halle (Saale) - Universitätsklinik und Poliklinik für Radiologie, Kinderradiologie

    Halle, Saxony-Anhalt, 06120, Germany

  • West China Second University Hospital

    Chengdu, Sichuan, 610041, China

  • Zhujiang Hospital of Southern Medical University

    Guangzhou, Guangdong, 510280, China

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