New cancer drug shows promise in early trial
NCT ID NCT05858164
First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 2 times
Summary
This early-phase study tested a new drug called BAY 2862789 in 45 people with advanced solid tumors, including non-small cell lung cancer. The drug works by activating immune cells to fight cancer. The main goals were to check safety, find the best dose, and see how the drug moves through the body. Participants took the drug until their cancer worsened or side effects became too severe.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AdventHealth medical Group Oncology Research at Celebration
Celebration, Florida, 34747, United States
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Asan Medical Center | Oncology
Seoul, 05505, South Korea
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Brigette Harris Cancer Pavilion at Henry Ford Cancer Center - Detroit
Detroit, Michigan, 48202, United States
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Chungbuk National University Hospital | Hematology and Oncology
Chungcheongbuk-do, North Chungcheong, 28644, South Korea
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Gyeongsang National University Hospital | Oncology
Jinju, Gyeongsangnam-do, 52727, South Korea
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Hadassah Hebrew University Hospital Ein Kerem
Jerusalem, 9112001, Israel
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Hospital Universitari Vall D Hebron | Oncologia
Barcelona, 08035, Spain
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Hospital Universitario Virgen De La Victoria | Oncologia
Málaga, 29010, Spain
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Jilin Cancer Hospital
Changchun, Jilin, 130000, China
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Princess Alexandra Hospital Australia
Woolloongabba, Queensland, 4102, Australia
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START | San Antonio
San Antonio, Texas, 78229, United States
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Seoul National University Hospital | Oncology
Jongno -Gu, Seoul, 03080, South Korea
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Seoul St Mary's Hospital | Oncology
Seoul, 06591, South Korea
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Tel- Aviv Sourasky Medical Center - Nephrology
Tel Aviv, 6423906, Israel
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The Kinghorn Cancer Centre - Medical Oncology Department
Darlinghurst, New South Wales, 2010, Australia
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Tongji Hosp. of Tongji Med Coll, Huazhong Uni of Sci & Tech.
Wuhan, Hubei, 430030, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can your own immune cells beat advanced cancer?
- Can a new immunotherapy combo outsmart advanced lung cancer?
- Double attack on mutant KRAS: can two targeted drugs outsmart resistant cancers?
- Seeing the fight: new imaging tracer may reveal how immune cells attack lung cancer
- Could a bronchial wash detect lung cancer mutations faster?
- Can a targeted pill outsmart a tough lung cancer mutation?