Can early jaw treatment in children prevent major surgery later?

NCT ID NCT07706400

Disease control Sponsor: Malmö University Source: ClinicalTrials.gov ↗

First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time

Summary

This study follows children aged 9–12 with an underdeveloped upper jaw (maxillary retrognathism) causing a reverse bite. They receive standard interceptive orthodontic treatments, such as facemasks or other appliances, to guide jaw growth. Researchers track changes in jaw position, dental health, and quality of life over 10 years to see which treatments work best.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: interceptive orthodontic treatment (e.g., facemask, reverse-pull headgear, or other appliances)
What this could lead to: If successful, this could help identify the most effective interceptive treatments for correcting jaw alignment in children, potentially reducing the need for surgery later.
What could go wrong: This is an observational study following standard care, not testing new treatments. Results may vary by clinic and patient compliance, and long-term stability is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 180 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Jul 2038

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

9 to 12 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Mandibular overjet due to maxillary retrognathia (Overjet \</= 0 mm) * Age 9-12 years * Informed consent from parents/guardians Exclusion Criteria: * Mandibular overjet mainly due to mandibular prognathism * Known general and/or craniofacial syndromes/diseases * Adenoid vegetations, hypertrophic tonsils and significantly reduced air passage through nose (mouth breathing), which must be primarily treated * Functional disorders in muscles and jaw joints, which must be primarily treated

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Conditions

The condition(s) this trial relates to.

autosomal dominant prognathism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Children Class III malocclusion Maxillary retrognathism Treatment

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

3 sites in 2 countries. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Can early jaw treatment in children prevent major surgery later?

What the study statuses mean