TREATMENT

This study is testing a gentle, pulsed laser treatment for diabetic macular edema, a common cause of vision loss where fluid swells the central part of the retina. It will compare how well the laser works for people with new cases versus cases that haven't responded well to other…

This study is testing a new antibody drug called Anti-CD38 for children aged 6 and up with immune thrombocytopenia (ITP), a condition that causes low platelet counts and bleeding risk. The trial is for kids who haven't gotten better or who relapsed after standard treatments. Rese…

This study is testing whether a drug called daratumumab works better than rituximab for children with immune thrombocytopenia (ITP), a condition that causes low platelet counts and bleeding risk. The trial is for children aged 6-18 whose ITP didn't improve or came back after stan…

This study is testing whether combining two existing drugs, rituximab and daratumumab, can help adults with a hard-to-treat form of immune thrombocytopenia (ITP). ITP is a condition where the immune system mistakenly attacks platelets, causing a risk of easy bruising and bleeding…

This study aims to understand why some patients with medication-overuse headache respond better to a specific nerve block treatment than others. Researchers will enroll 70 adults to examine patient characteristics like pain sensitivity, anxiety, and sleep quality before treatment…

This study is testing whether adding a second drug (anti-CD38) to a standard treatment (rituximab) works better for adults with immune thrombocytopenia (ITP) whose platelet counts stayed low after steroid therapy. Researchers will compare the safety and effectiveness of the two-d…

This early-stage study is testing whether stem cells taken from amniotic fluid can help heal the extremely painful and dangerous skin wounds caused by calciphylaxis, a rare complication of kidney disease. Nine adult patients with calciphylaxis will receive the stem cell treatment…

This study is testing whether a drug called Daratumumab works better than the standard drug Rituximab for adults with immune thrombocytopenia (ITP), a condition that causes low platelets and bleeding risk. It's for people whose ITP didn't get better or came back after initial ste…

This study tests whether switching medications early can help smokers who struggle to quit. Participants receive free quit-smoking products for 12 weeks, and the treatment plan adjusts based on their initial progress. The study is conducted entirely remotely with 544 smokers acro…

This study is testing a new combination of three drugs (venetoclax, ivosidenib, and azacitidine) for adults with a specific genetic form of acute myeloid leukemia (AML) who are eligible for intensive chemotherapy. The main goals are to find the safest dose of this triple-drug reg…

This study is testing a new combination of cancer drugs for children, teens, and young adults (ages 2-35) newly diagnosed with classical Hodgkin lymphoma. The main goal is to improve the rate of early, complete response to treatment, which could allow more patients to avoid radia…

This study is testing whether a combination of traditional Chinese herbal medicine and small, shallow acupuncture needles can help slow down early puberty in girls. Researchers want to see if this approach can reduce early breast development and delay bone maturation compared to …

This study is testing which of two stomach acid-reducing medicines works better as part of a standard 4-drug treatment for H. pylori infection, a common stomach bacteria. Researchers will compare how well each combination clears the infection, how safe they are, and how easy they…

This study is testing two new designs of eyeglass lenses to see if they can slow down how quickly nearsightedness (myopia) gets worse in children. About 120 kids, aged 6 to 14, will wear one of the two lens types daily for a year and have regular eye check-ups. The main goal is t…