High-Dose exercise may speed concussion recovery in teens
NCT ID NCT05434130
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether high-dose aerobic exercise (over 150 minutes per week at a safe intensity) helps teens aged 13–18 recover faster from a concussion compared to standard care. Researchers will track symptom resolution, brain inflammation markers, and changes in anxiety and depression. The goal is to create better rehabilitation guidelines for young athletes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
high dose aerobic exercise
What this could lead to
If it works, this could lead to more precise exercise guidelines for teens recovering from concussion, potentially speeding up symptom relief and reducing long-term anxiety or depression.
What could go wrong
This is a Phase 2 trial with 216 participants, so results are still early. Exercise may not speed recovery for everyone, and some teens might find the high dose too difficult or risky.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Boston Children's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
Contact
Contact
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Spaulding Rehabilitation Hospital
RECRUITINGCambridge, Massachusetts, 02138, United States
Contact
Contact
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University of Colorado Denver
RECRUITINGAurora, Colorado, 80045, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••