University Of Colorado, Denver

This study aims to see if providing educational videos and materials helps more people in underserved communities start and complete the HPV vaccine series. The study involves 1,000 participants, including adolescents (9-17) and young adults (18-26) who haven't yet received the v…

This study looks at how well the shingles vaccine (Shingrix) works and how safe it is in adults with kidney failure who are waiting for a kidney transplant. Some participants will get an extra dose of the vaccine after their transplant to see if it improves their immune protectio…

This study looks at how well the shingles vaccine (Shingrix) works in people who have had a stem cell transplant. About 55 adults who received the vaccine at least one year after their transplant will have their immune responses measured. Researchers want to find the best time to…

This study tests a program called NAVIGATE-Kidney for people with advanced chronic kidney disease. The goal is to help them start kidney replacement therapy (dialysis or transplant) without needing a temporary catheter, which can lead to infections. About 448 adults will take par…

This study compares the iLet Bionic Pancreas, an automated insulin delivery system, to usual care for adults with type 1 or type 2 diabetes who use insulin. About 240 participants will use the device or continue their routine care for 13 weeks to see if it improves blood sugar co…

This study tests whether giving two drugs (pembrolizumab and axitinib) before surgery can shrink tumor-related blood clots in the main vein of people with kidney cancer. The goal is to make surgery easier and safer, and to improve long-term outcomes. About 17 adults with clear ce…

This study tests two school-based programs to help children ages 5-12 from low-income communities in Colorado better manage their asthma. The goal is to reduce asthma attacks and missed school days by having school nurses and navigators coordinate care with doctors and community …

This study is for people with rectal cancer that didn't fully go away after standard chemotherapy and radiation. Instead of moving straight to surgery, doctors will give extra internal radiation (brachytherapy) directly to the remaining tumor. The goal is to see if this can compl…

This study looks at whether people with stable relapsing multiple sclerosis (MS) can safely switch from a strong infusion therapy (anti-CD20) to a daily pill (ozanimod). The goal is to see if the pill can keep the disease under control with fewer serious infections. About 100 adu…

This study tests a new type of immune cell therapy (CAR-T) for children and teens whose B-cell leukemia or lymphoma has come back or not responded to standard treatments. The therapy uses the patient's own immune cells, modified to target and kill cancer cells. The goal is to see…

This study is testing whether giving a lower dose of the chemotherapy drug doxorubicin weekly, instead of the standard higher dose every three weeks, is effective and easier to tolerate for older patients (ages 65-100) with advanced soft tissue sarcoma. The main goal is to see if…

This study tests whether semaglutide, a drug already used for type 2 diabetes, can improve heart and kidney function in adults with type 1 diabetes. Researchers will measure artery stiffness, insulin sensitivity, and kidney blood flow in 60 participants over the course of the tri…

This study looks at whether placing vending machines that dispense naloxone (a medication that reverses opioid overdoses) in communities can help more people get this life-saving drug. Researchers will track how many naloxone kits are distributed before and after installing the m…

This study tests whether coating small dental screws (miniscrews) with an antimicrobial substance called K21 can reduce inflammation and improve stability in orthodontic patients. About 30 people who need at least two miniscrews as part of their treatment will participate. Each p…

This study looks at whether a team-based mental health program can help pregnant and new mothers living with HIV in Kenya feel better and stay healthy. About 900 women will receive extra mental health support alongside their regular HIV care. The goal is to reduce depression and …

This study tests a drug called sargramostim, already approved for bone marrow stimulation, in people with mild-to-moderate Alzheimer's disease. Over six months, 42 participants will receive either the drug or a placebo to see if it is safe and helps with thinking and memory. The …

This early-stage trial tests a combination of two drugs, CC-486 and venetoclax, in people with acute myeloid leukemia (AML) whose cancer has returned or not responded to treatment, as well as some newly diagnosed patients. The main goal is to find the safest dose of CC-486 when g…

This early-phase trial tests a new type of immunotherapy called CD19x22 CAR T cells in people aged 16 and older with B-cell non-Hodgkin lymphoma that has come back or not responded to treatment. The therapy uses the patient's own immune cells, modified to attack two targets on ca…

This study tests a new, single-use digital scope (Dragonfly™) for treating bile duct stones and taking tissue samples. Up to 75 adults with bile duct stones or narrow bile ducts will use this scope during a standard endoscopy procedure. The goal is to see how well the scope break…

This early-phase study tests a combination of losartan (a blood pressure medicine) and sunitinib (a targeted cancer drug) in people aged 10 and older with osteosarcoma that has returned or stopped responding to standard treatments. The main goals are to find the safest dose and t…

This study tests a new drug combination for adults with acute myeloid leukemia (AML) whose cancer did not respond to or came back after standard treatment. About 30 participants will receive mitoxantrone added to their current therapy to see if it can safely improve outcomes. The…

This early-phase trial tests whether adding chemotherapy directly into the abdomen (intraperitoneal paclitaxel) to standard vein chemotherapy (NALIRIFOX) is safe and effective for adults with pancreatic cancer that has spread to the lining of the belly. Ten participants will rece…

This study looks at whether a set of health interventions can help women going through menopause reduce inflammation, improve heart health, slow biological aging, and ease symptoms like hot flashes. Researchers will enroll 200 women aged 45-55 who are in late menopause transition…

This study tests a special gel (VersaWrap) placed between the metal plate and tendons during wrist fracture repair surgery. The goal is to see if the gel helps tendons move more smoothly and reduces the chance of tendon rupture. About 50 adults having wrist fracture surgery will …

This study tests whether an accelerated form of brain stimulation (TMS) can help people with moderate to severe methamphetamine use disorder reduce their drug use and cravings. Twenty participants will receive either real or sham TMS to see if the treatment is safe, tolerable, an…

This early-phase trial tests whether a new type of CAR T cell therapy (UCD19) is safe and can work in adults with B-cell acute lymphoblastic leukemia (B-ALL) who are in first remission but still have tiny amounts of cancer cells (minimal residual disease). About 29 participants w…

This study tests whether brexpiprazole, a medication that balances brain chemicals, can help people with alcohol use disorder drink less. Researchers will also check if a specific gene (DAT1) makes the drug work better for some people. The study involves 250 adults who are not se…

This study tests whether adding the drug ruxolitinib to a standard stem cell transplant regimen can lower the chance of transplant failure in children and young adults with severe sickle cell disease. About 24 participants aged 12-45 will receive a transplant from a half-matched …

This study looks at whether full-spectrum cannabidiol (CBD) can help people who drink alcohol regularly cut back. Researchers will give CBD to 150 adults aged 21-65 and track their drinking habits over 12 weeks. The goal is to see if CBD reduces the number of drinks people have a…

This study tests whether cannabidiol (CBD) can help people who regularly use high-potency cannabis concentrates reduce their use and cravings. About 120 adults aged 25-60 who use concentrates at least 4 times a week but aren't trying to quit will take CBD (200 or 400 mg daily) or…

This study tests whether hemp-derived CBD can help young adults (ages 18-25) who use cannabis at least 5 days a week reduce their cannabis use and related harm. Participants are not trying to quit and will take either CBD or a placebo for 8 weeks. The study measures changes in ca…

This study is testing whether a combination of two drugs, mirvetuximab soravtansine and olaparib, can help keep recurrent ovarian, peritoneal, or fallopian tube cancer from growing back after initial treatment. The trial involves 53 women whose cancer has returned but still respo…

This study tests a combination of two drugs, cladribine and venetoclax, in adults with a specific type of acute myeloid leukemia (monocytic AML) that came back or didn't get better after standard treatment. The goal is to see how many patients achieve remission or significant blo…

This study looks at whether metformin, a drug used for diabetes, can help prostate cancer patients who have high blood sugar or are overweight. About 100 men will either get metformin plus lifestyle advice or just lifestyle advice. The goal is to see if this approach is practical…

This study is for people under 30 with disorders of sex development who are at high risk of infertility or ovarian cancer. Researchers will remove and freeze ovarian tissue before it is surgically removed for medical reasons. The goal is to see if this tissue can later be used to…

This early-phase study tests a new two-drug combination (Cirtuvivint and Olaparib) in people with ovarian, peritoneal, or fallopian tube cancer that no longer responds to platinum chemotherapy. About 50 participants will take the pills at different schedules to find the safest do…

This study tests a new type of CAR T-cell therapy that targets two proteins (CD19 and CD22) on leukemia cells. It is for children whose B-cell acute lymphoblastic leukemia has returned or not responded to standard treatments. The goal is to see if this therapy is safe and can shr…

This pilot study tests whether a home urine test can accurately measure pregnancy hormone (hCG) levels compared to standard blood tests. About 35 women with a pregnancy of unknown location (PUL) and non-pregnant controls will collect daily urine samples at home and have blood dra…

This study tests a telehealth version of a fall prevention program for older adults who come to the emergency department after a fall. Participants will receive physical therapy and pharmacy consultations by video while still in the ER, then be followed for 6 months. The goal is …

This study aims to see if a standardized program can increase flu vaccination rates for children while they are in the hospital. Researchers will work with parents, doctors, and nurses to create a best-practice guide and test it across multiple US children's hospitals. About 22,0…

This study tests a low-cost, one-hour program called CARE to prevent mood, anxiety, and trauma symptoms after cesarean delivery. It is for pregnant people at high risk due to medical complications. The program includes education and a brief exposure to the operating room to reduc…

This study tests a program that automatically notifies older adults (65+) who are at high risk of falling about their risk and connects them to local fall prevention classes. The goal is to reduce fall-related emergency room visits. About 20,700 participants will be enrolled acro…

This study tests whether the asthma drug Advair HFA can prevent high altitude pulmonary edema (HAPE), a condition where fluid fills the lungs at high altitudes, causing breathing difficulty. Researchers will give the drug or a placebo to 60 healthy and HAPE-prone adults and measu…

This early-phase study tests whether a single dose of psilocybin, given with therapy, can reduce the intense fear of cancer returning in women who have completed treatment for early-stage breast or ovarian cancer and are now in remission. Twenty participants will receive preparat…

This study tests a new approach called Pain Reprocessing Therapy (PRT) for adults with ongoing knee pain after knee replacement surgery. PRT teaches the brain to reinterpret pain signals, aiming to reduce pain without medication. About 110 participants will be randomly assigned t…

This study is testing a new exercise program for people with knee osteoarthritis. The program uses a special machine to strengthen muscles during the lengthening phase of movement. Researchers want to see if this training helps people climb stairs more smoothly and safely, and re…

This study is testing whether oral cannabis can safely reduce chronic back or neck pain and help people cut down on strong painkillers like opioids. About 157 adults with long-term spine pain will take cannabis pills or a placebo for several weeks. Researchers will measure pain l…

This study compares a combination of ibuprofen and acetaminophen against ibuprofen alone or a placebo for managing pain after getting braces. 375 people starting orthodontic treatment will rate their pain on a scale. The goal is to see if the combination provides better pain cont…

This study tests a program called ALIGN, which provides virtual palliative care visits for older adults with advanced cancer who are moving to a skilled nursing facility. The goal is to see if this approach is practical and helps patients and their family caregivers feel supporte…

This study tests if a short course of steroids given through a vein can reduce swelling in the throat and improve swallowing in people who have recently had a breathing tube. The trial involves 80 adults who are already part of a larger study and have throat swelling seen on a ca…

This study looks at whether a supervised exercise program (cardiac rehab) can improve daily function and quality of life for people with Long COVID. Researchers will also measure heart and lung responses to understand why symptoms occur. The study enrolls 30 adults who have had L…

This study looks at whether a continuous infusion of the numbing medicine bupivacaine through a pump placed in the incision after a C-section helps reduce the need for stronger painkillers like opioids. About 100 pregnant women having C-sections at the Colorado Fetal Care Center …

This study aims to make a high-intensity exercise program safe and easy to do at home for people with Parkinson's disease. It also tests a headband that tracks sleep. Sixteen participants in Colorado will try the program and give feedback. The goal is to improve access to exercis…

This study tests whether 12 weekly sessions of parent management training can reduce irritability, anger outbursts, and cranky moods in children aged 10-14. Parents attend the training while children complete assessments. The goal is to see if this approach works in a clinic sett…

This study is testing whether a Spanish-language program called Unstuck and On Target can help children ages 8-11 with autism or ADHD improve their executive functioning skills, like planning and flexibility. About 40 Spanish-speaking families will either join the program right a…

This study tests a procedure called genicular artery embolization (GAE) for people with knee osteoarthritis. The goal is to see if blocking certain blood vessels in the knee can reduce pain and inflammation. About 46 adults with persistent knee pain will get MRIs, questionnaires,…

This study tests whether socks made with semiconductor fabric can improve healing and reduce symptoms after an ankle sprain. About 100 adults with ankle injuries will wear either the special socks or regular compression socks and report their pain and function over time. The goal…

This study tests whether Pain Reprocessing Therapy (PRT) helps veterans with chronic back or neck pain more than Cognitive Behavioral Therapy (CBT) or usual care. About 360 veterans will be randomly assigned to one of the three groups. Those in PRT or CBT will have nine weekly vi…

This study tests whether a special sleep health program helps teens aged 10–19 recover faster from a concussion. About 54 participants will either receive the sleep program or standard sleep advice. The goal is to see if better sleep leads to quicker symptom relief, improved mood…

This study tests whether a higher amount of aerobic exercise, started within two weeks of a concussion, helps teenagers recover faster. Researchers will measure symptom relief, brain inflammation markers, and changes in anxiety or depression. The goal is to create better, more pr…

This study tests whether a telehealth exercise program can reduce cancer-related fatigue in rural breast and prostate cancer survivors. About 134 participants will receive personalized virtual exercise coaching and collect small blood samples at home to track changes. The goal is…

This study tests whether using gentle electrical pulses on the thigh muscle can help people regain leg strength and movement faster after total knee replacement. About 3,250 patients will be randomly assigned to receive either standard physical therapy or standard therapy plus el…

This study tests whether a one-month treatment combining the drug clemastine fumarate with engineered sound can improve the ability to hear speech in background noise for adults aged 45-65 with age-related central auditory processing disorder (CAPD). About 344 participants will b…

This study tests a digital program called TPA4You that uses a Fitbit to help older adults (50+) who care for a family member with heart failure become more active. The goal is to see if the program is practical and can improve daily activity, reduce sitting time, and ease caregiv…

This study looks at how insulin resistance in type 2 diabetes reduces blood flow to muscles and the heart, leading to poor exercise ability. Researchers will test if 15 weeks of exercise training can improve insulin sensitivity and heart function. The study involves 150 sedentary…

This study tests a new ultrasound method that uses tiny bubbles to measure blood flow in the pancreas. The goal is to see if these measurements can help detect type 1 diabetes early. Researchers will compare 50 healthy adults and those recently diagnosed with type 1 diabetes to f…

This study looks at three different ways to help people improve their health habits, like eating more fruits and vegetables, being more active, and reducing stress. About 1,000 adults who already completed a health check will be assigned to one of three follow-up plans or a contr…

This study looks at whether giving extra support and coaching to primary care clinics helps them better use a suicide prevention program for youth ages 12-24. About 360 participants will be involved. The goal is to see if this approach leads to more screening, better care, and fe…

This study looks at how losing weight affects the fat stored inside your muscles, called IMAT. Researchers want to see if this fat makes muscles less responsive to insulin and causes inflammation, and if weight loss can reverse that. About 70 adults with obesity will follow a 12-…

This study is for teens and young adults aged 12 to 24 who are planning to have weight loss surgery (sleeve gastrectomy). Researchers want to understand how the body changes after surgery and why some people lose more weight than others. For those who haven't lost enough weight 1…

This study tests whether a new type of imaging (shear-wave elastography and MRI) can detect damage to the uterus caused by pelvic radiation. Researchers will enroll 22 women who had pelvic radiation before age 40 and compare their scans to those without radiation. The goal is to …

This study looks at 750 adults with rheumatoid arthritis (RA) who are at risk for developing interstitial lung disease (ILD). Researchers use chest CT scans and track changes over 3-5 years to find early signs and risk factors. The goal is to better understand who might develop l…

This study looks at whether exercising in the morning or evening makes a difference in weight loss for people who are overweight. Researchers will track 128 adults over 13 months, measuring weight, body fat, sleep, and eating habits. The goal is to find out if timing your workout…

This study looks at tumor samples from 500 adults with lung or chest cancers to find genetic changes that make targeted therapies stop working. Participants provide tissue from routine biopsies or procedures. The goal is to learn how cancers become resistant, not to test a new tr…

This study follows 400 men with solid tumors to understand how cancer care impacts their ability to work and their overall well-being. It focuses on low-income and Latino men, who often face extra challenges. Researchers will track employment hours, mental health, and financial s…

This study is testing a device called Electrical Impedance Tomography (EIT) that creates images of the lungs without using radiation. It will be used in children with chronic lung diseases, neuromuscular disorders, and healthy volunteers to see if it can provide useful informatio…

This study looks at how the right side of the heart works during rest and exercise in people with COPD. Researchers want to find different patterns of heart strain to guide future treatments. About 60 adults aged 40 and older with COPD will take part. The goal is to better unders…

This study follows 200 babies diagnosed with intra-uterine growth restriction (IUGR) using advanced imaging to track subtle changes in the brain, heart, and placenta over time. Researchers will link these findings to the babies' development after birth and in early childhood. The…

This study looks at whether short-term use of NSAID pain relievers (like ibuprofen) after surgery increases the risk of acute kidney injury in children with mild-to-moderate chronic kidney disease. About 80 children aged 18 months and older will be monitored. The goal is to gathe…

This study tests if a gentle electrical pulse on the ear can improve decision-making and problem-solving. Researchers will include healthy adults, people with mild cognitive impairment, and those with Parkinson's disease. The goal is to see if this safe, non-invasive method can b…

This study looks at whether a single dose of equol, a substance made when digesting soy, can improve blood vessel function in postmenopausal women. It includes 38 women aged 50-69, some with chronic kidney disease (CKD) and some healthy. Researchers will measure blood vessel heal…

This study looks at why pregnant women living at high altitude have higher rates of poor fetal growth and preeclampsia. Researchers will collect tissue samples from 84 women having scheduled C-sections in Denver (low altitude) and Summit County (high altitude). By comparing blood…

This study tests whether training ICU staff to keep oxygen levels in a specific range (90-96%) helps patients on breathing machines. Researchers will track how many days patients are free from the ventilator and how often dangerously low oxygen goes unnoticed. The goal is to impr…

This study collects tissue and blood samples from 2,000 people being tested or treated for lung cancer. The samples are stored in a bank for future research, with the goal of helping scientists find better ways to detect, treat, and prevent lung cancer. Participants give consent …

This study looks at whether freezing testicular tissue is a safe and acceptable way to preserve fertility in males of any age who are about to receive treatments that could cause infertility. Up to 60 participants will be enrolled to see how many choose the procedure and how many…

This study looks at how the stiffness of a prosthetic foot affects people who have a bone-anchored limb after a below-knee amputation. Researchers will have 60 participants walk and do daily tasks with different foot stiffness levels to measure bone-implant stress, function, pain…

This study looks at how the right side of the heart works in people with COPD, both at rest and during different levels of exercise. Researchers want to find patterns of heart dysfunction that could lead to better treatments. The study involves 60 adults aged 40 and older with CO…

This study looks at how drinking alcohol and the way couples talk about sex can influence sexual violence between partners. Researchers will bring 240 couples to a lab, give some alcohol and some a non-alcoholic drink, and ask them to communicate in different styles. The goal is …

This study looks at whether people with HIV can collect their own blood samples at home using a simple finger prick. The goal is to see if these home samples give the same results as clinic blood draws for measuring HIV drug levels. About 150 adults already taking HIV treatment o…

This study tests a program called CARES that provides advocacy, resources, education, and support to rural cancer patients. The goal is to see if it helps them start treatment sooner after diagnosis and finish it faster. The study will include 320 adults with solid tumors like lu…

This study follows 1000 children and young adults (ages 10-25) who have had a total joint replacement for reasons other than cancer. Researchers want to understand how these surgeries affect their daily function and quality of life over time. Participants will fill out standard q…

This study works with Spanish-speaking families who have a child with leukemia or lymphoma. Researchers will interview parents and patients to understand their experiences and find out how language barriers affect their care. The goal is to improve communication and build a stron…

This study looks at why some lung cancer cells survive targeted treatment. Researchers will take small tissue samples (biopsies) before and two weeks after starting therapy to spot early signs of resistance. The goal is to find ways to block these survival pathways and make treat…

This study looks at the best way to manage Barrett's esophagus with low-grade dysplasia, a condition where the esophagus lining has abnormal but not yet cancerous cells. Researchers will compare two common approaches: regular check-ups with biopsies (surveillance) versus a proced…

This study is testing a 24-week program that combines nutrition counseling, exercise, sleep tips, and stress management for cancer survivors who are overweight. Researchers want to see if the program is practical and helpful for improving sleep quality, reducing stress, and boost…

This study works with Spanish-speaking parents, interpreters, and doctors to create educational videos about childhood cancer. The goal is to see if these videos help caregivers better understand their child's care and feel more supported. Ten families will help test the videos, …

This study aims to understand why people have different eye movement patterns when searching for something visually. Researchers will measure attention and self-control abilities in 225 adults aged 18-65, then see how these skills relate to eye movements during a computer task. T…

This study looks at how romantic partners who both smoke can help each other quit. Researchers will ask 250 couples to fill out daily surveys for two weeks while trying to quit. The goal is to learn which types of support work best so future programs can help couples quit togethe…

This study looks at whether changes in the natural bacteria living in your mouth and gut (the microbiome) play a role in head and neck cancer. Researchers will collect stool and saliva samples from 60 adults—some with cancer and some without—to compare their microbiomes. The goal…

This study looks at how a woman's immune system reacts to breast cancer, especially if she has been pregnant before. Researchers will follow 800 young women with breast cancer to understand these interactions. The goal is to learn more, not to test a new treatment.

This study is testing whether psilocybin, the active ingredient in magic mushrooms, is safe and tolerable for healthy adults aged 65 to 85. About 40 participants will receive the drug and be monitored for side effects. The goal is to gather safety data, not to treat any disease.

This study looks at how the autonomic nervous system (which controls heart rate and blood pressure) works in people with Down syndrome. Researchers will measure heart rate, blood pressure, and stress hormones during activities like cold water, fear simulations, exercise, and caff…

This study aims to create a mindfulness program for people with metastatic colorectal cancer and their partners to help reduce stress. Researchers will interview about 48 patients, partners, and doctors to learn what topics and formats work best. The goal is to design a program t…

This study looks at sputum and tissue samples from 700 people with or without precancerous changes in the airways. The goal is to find biomarkers—biological clues—that may help detect lung, head and neck, or esophageal cancer earlier. Participants provide samples during routine p…

This study tests whether a special ultrasound dye can help brain surgeons tell the difference between tumor tissue and healthy brain during glioma surgery. The goal is to remove as much tumor as possible. About 100 adults having standard brain tumor surgery will receive the contr…

This study examines whether two common chemotherapy drugs, vincristine and doxorubicin, cause lasting bladder problems in children who have completed cancer treatment. Researchers will measure urine flow, bladder emptying, and specific substances in the urine of 152 children aged…

This study tests a program called Pediatric Medication Therapy Management (pMTM) to help doctors and families better manage the many medications children with complex health conditions take. The goal is to find and fix medication-related problems, like drug interactions or unnece…

This study is not testing a new treatment. Instead, it aims to improve cancer care by collecting blood, tissue, and other samples along with health information from 20,000 people who have cancer or are at risk. Researchers will use this data and samples to learn more about cancer…

This study looks at how eating different snacks, like walnuts or pretzels, changes brain activity related to food cravings and fullness during a 12-week weight-loss diet. Researchers will use brain scans to measure responses to food pictures and track changes in body fat and appe…

This study collects placenta tissue, umbilical cord blood, and maternal blood from 1,250 pregnant women at delivery. Researchers will use these samples to learn how the placenta changes in healthy and complicated pregnancies, and how those changes may affect the baby's long-term …

This study creates a large collection of blood, saliva, urine, and other samples from 2,500 people with and without Down syndrome. Researchers will use these de-identified samples and medical records to better understand the health conditions that often accompany Down syndrome. T…

This study looks at how different behavioral programs that change the way people think about food affect brain activity, eating habits, and body weight. About 228 adults with a BMI of 27 or higher will take part. Researchers will use brain scans and food intake tests to see what …

This study partners with community organizations and trusted local members to improve health research participation among Black, Latino, and Native American communities in Colorado. It focuses on understanding and addressing health issues like mental health, high blood pressure, …

This study uses a new, radiation-free machine called Electrical Impedance Tomography (EIT) to look at the lungs of children from 2 weeks to 25 years old. Researchers will compare kids with chronic lung problems to healthy kids to learn more about lung structure and function. The …

This study is creating a detailed atlas of pre-cancerous spots in the lungs to understand how they turn into cancer. Researchers will collect tissue samples from 240 adults with these spots using a scope down the airway. The goal is to find clues that could help prevent lung canc…

This study looks at whether removing a menstrual cup the right way (by breaking the seal) can cause an IUD to shift or come out. Researchers will measure how often the IUD moves more than 1 cm after cup removal. The goal is to help doctors give better advice to people who use bot…

This study tests a wearable 'smart underwear' device that measures hydrogen sulfide gas produced by gut microbes after eating different diets. About 25 healthy adults will wear the device during the day while following two special diets (high and low cysteine) in random order. Th…

This study looks at whether giving people with type 2 diabetes a Fitbit and sending them personalized text messages can help them become more active and improve their health. About 36 adults who are not very active will wear a Fitbit and answer texts for 12 weeks. The goal is to …

This study aims to understand how brain cells work when people with Parkinson's disease perform thinking tasks. Researchers will insert a thin probe into the brain for a short time during planned deep brain stimulation surgery. The goal is to learn more about brain function, not …