University Of Colorado, Denver

This study looks at how well the shingles vaccine (Shingrix) works in people who have had a stem cell transplant. Researchers want to find the best time to give the vaccine after transplant and whether a third dose helps. About 55 adults who already received two doses of Shingrix…

This study aims to see if providing educational videos and materials helps more people in underserved communities start and complete the HPV vaccine series. The study involves 1,000 participants, including adolescents (9-17) and young adults (18-26) who haven't yet received the v…

This study looks at how well the shingles vaccine (Shingrix) works and how safe it is in adults with kidney failure who are waiting for a kidney transplant. Some participants will get an extra dose of the vaccine after their transplant to see if it improves their immune protectio…

This study tests a new combination of drugs for people with acute myeloid leukemia (AML) whose cancer did not respond to or came back after standard treatment. About 30 adults will receive mitoxantrone along with venetoclax and azacitidine to see if this mix can shrink the cancer…

This study tests whether a drug called tofacitinib, which calms the immune system, can improve thinking and daily skills in people with Down syndrome aged 6 to 22. Participants take the drug or a placebo for 6 months, and researchers check for side effects and changes in memory, …

This study is for people aged 65-100 with advanced or metastatic leiomyosarcoma, a rare soft tissue cancer that cannot be removed by surgery. Researchers want to see if giving the standard chemotherapy drug doxorubicin at a lower dose every week (instead of a higher dose every fe…

This study is testing whether semaglutide, a drug already used for type 2 diabetes, can improve heart and kidney function in adults with type 1 diabetes. Researchers will measure artery stiffness and insulin sensitivity in 60 participants over time. The drug is not yet FDA-approv…

This early-phase study tests a new type of cell therapy (CD19x22 CAR T) for adolescents and adults with B-cell non-Hodgkin lymphoma that has come back or not responded to treatment. The therapy uses a patient's own immune cells, modified to target two proteins on cancer cells. Th…

This study is for women with ovarian, peritoneal, or fallopian tube cancer that has come back but still responds to platinum-based chemotherapy. The goal is to see if taking two drugs together (mirvetuximab soravtansine and olaparib) as maintenance therapy can delay the cancer fr…

This study tests whether cannabidiol (CBD), a non-psychoactive compound from the cannabis plant, can help people who regularly use high-potency cannabis concentrates reduce their use and cravings. About 120 adults aged 25-60 who use cannabis concentrates at least 4 times a week b…

This study tests a new single-use digital scope (Dragonfly™) for treating bile duct stones and taking tissue samples. Up to 75 adults with bile duct stones or narrow bile ducts will use this scope during a standard endoscopy procedure. The goal is to see how well the scope breaks…

This study tests whether full-spectrum cannabidiol (CBD) can help people who regularly drink alcohol reduce their drinking. Researchers will measure how much participants drink in a lab setting and track their drinking habits over 12 weeks. The goal is to see if CBD can be a safe…

This study tests whether adding the drug ruxolitinib to a standard stem cell transplant can prevent the transplant from failing in children and young adults with severe sickle cell disease. About 24 participants aged 12 to 45 will receive the treatment and be followed for 2 years…

This study tests a special gel (VersaWrap) placed between the metal plate and tendons during wrist fracture repair. The goal is to see if the gel helps tendons glide more smoothly and reduces the chance of tendon rupture. About 50 adults having wrist fracture surgery will take pa…

This study tests a new type of cell therapy (CD19x22 CAR T) in children whose B-cell acute lymphoblastic leukemia has come back or not responded to standard treatments. The therapy uses the patient's own immune cells, modified to attack two targets on leukemia cells. The main goa…

This study tests whether giving extra internal radiation (brachytherapy) to rectal cancer patients who still have some tumor after standard treatment can completely eliminate the cancer and avoid the need for surgery. About 44 adults will receive three weekly outpatient treatment…

This study tests whether a drug called brexpiprazole can help people with alcohol use disorder drink less. Researchers will also check if a person's genes affect how well the drug works. About 250 adults who are not seeking treatment will take either the drug or a placebo and rep…

This early-phase trial is testing whether combining losartan (a blood pressure drug) with sunitinib (a targeted cancer drug) is safe and tolerable for people aged 10 and older with osteosarcoma that has returned or stopped responding to standard treatments. The study will first f…

This study compares a smart insulin pump called the iLet Bionic Pancreas to usual diabetes care for adults with type 1 or type 2 diabetes who use insulin. About 240 participants will use the pump or continue their routine care for 13 weeks to see if the pump improves blood sugar …

This study tests a combination of two drugs, cladribine and venetoclax, in about 20 adults with a specific type of acute myeloid leukemia (monocytic AML) that came back or didn't respond to standard venetoclax-based therapy. The main goal is to see how many people achieve remissi…

This study looks at whether placing naloxone in vending machines helps more people get this overdose-reversing drug. Researchers will track how many naloxone kits are distributed before and after installing machines in communities. Anyone in the community can use the machines, an…

This study tests a program called NAVIGATE-Kidney for 448 adults with advanced chronic kidney disease. The goal is to help patients start kidney replacement therapy (dialysis or transplant) in a planned way, avoiding emergency starts with a central venous catheter. The program in…

This early-stage study is testing whether combining two drugs, Cirtuvivint and Olaparib, is safe for people with ovarian cancer that has stopped responding to platinum-based chemotherapy. About 50 adults with specific genetic markers (BRCA/HRD) will take part. The main goal is to…

This study tests whether giving two drugs (pembrolizumab and axitinib) before surgery can shrink tumor-related blood clots in the main vein of people with kidney cancer. The goal is to make surgery easier and safer, and to improve long-term outcomes. About 17 adults with clear ce…

This study tests two school-based programs to help children ages 5-12 from low-income communities in Colorado better manage their asthma. The goal is to reduce asthma attacks and missed school days by having school nurses and navigators coordinate care with doctors and community …

This study looks at whether people with stable relapsing multiple sclerosis (MS) can safely switch from a strong infusion therapy (anti-CD20) to a daily pill (ozanimod). The goal is to see if the pill can keep the disease under control with fewer serious infections. About 100 adu…

This study tests a new type of immune cell therapy (CAR-T) for children and teens whose B-cell leukemia or lymphoma has come back or not responded to standard treatments. The therapy uses the patient's own immune cells, modified to target and kill cancer cells. The goal is to see…

This study looks at whether a team-based mental health program can help pregnant and new mothers living with HIV in Kenya feel better and stay healthy. About 900 women will receive extra mental health support alongside their regular HIV care. The goal is to reduce depression and …

This early-stage trial tests a combination of two drugs, CC-486 and venetoclax, in people with acute myeloid leukemia (AML) whose cancer has returned or not responded to treatment, as well as some newly diagnosed patients. The main goal is to find the safest dose of CC-486 when g…

This early-phase trial tests whether adding chemotherapy directly into the abdomen (intraperitoneal paclitaxel) to standard vein chemotherapy (NALIRIFOX) is safe and effective for adults with pancreatic cancer that has spread to the lining of the belly. Ten participants will rece…

This study looks at whether a set of health interventions can help women going through menopause reduce inflammation, improve heart health, slow biological aging, and ease symptoms like hot flashes. Researchers will enroll 200 women aged 45-55 who are in late menopause transition…

This study tests whether an accelerated form of brain stimulation (TMS) can help people with moderate to severe methamphetamine use disorder reduce their drug use and cravings. Twenty participants will receive either real or sham TMS to see if the treatment is safe, tolerable, an…

This early-phase trial tests whether a new type of CAR T cell therapy (UCD19) is safe and can work in adults with B-cell acute lymphoblastic leukemia (B-ALL) who are in first remission but still have tiny amounts of cancer cells (minimal residual disease). About 29 participants w…

This study tests whether hemp-derived CBD can help young adults (ages 18-25) who use cannabis at least 5 days a week reduce their cannabis use and related harm. Participants are not trying to quit and will take either CBD or a placebo for 8 weeks. The study measures changes in ca…

This study looks at whether metformin, a drug used for diabetes, can help prostate cancer patients who have high blood sugar or are overweight. About 100 men will either get metformin plus lifestyle advice or just lifestyle advice. The goal is to see if this approach is practical…

This pilot study tests whether a home urine test can accurately measure pregnancy hormone (hCG) levels compared to standard blood tests. About 35 women with a pregnancy of unknown location (PUL) and non-pregnant controls will collect daily urine samples at home and have blood dra…

This study tests a program that automatically notifies older adults (65+) who are at high risk of falling when they visit the emergency room. It connects them to local fall prevention programs. The goal is to reduce future fall-related ER visits and help people stay safe at home.

This study aims to prevent mood, anxiety, and trauma symptoms after cesarean delivery. Researchers will refine a one-hour program that teaches coping skills and gives a preview of the operating room. The program will be tested with 80 pregnant people at high risk for C-section to…

This study tests a telehealth version of a fall prevention program for older adults who come to the emergency department after a fall. Participants will receive physical therapy and pharmacy consultations by video while still in the ER, then be followed for 6 months. The goal is …

This study aims to see if a standardized program can increase flu vaccination rates for children while they are in the hospital. Researchers will work with parents, doctors, and nurses to create a best-practice guide and test it across multiple US children's hospitals. About 22,0…

This study tests whether the asthma drug Advair HFA can prevent high altitude pulmonary edema (HAPE), a condition where fluid fills the lungs at high altitudes, causing breathing difficulty. Researchers will give the drug or a placebo to 60 healthy and HAPE-prone adults and measu…

This study looks at whether doing more aerobic exercise (at a safe level) within two weeks of a concussion helps teenagers feel better faster. Researchers will track symptoms, brain markers, and mood changes in 216 teens aged 13-18. The goal is to find the best exercise plan to i…

This study tests a program called ALIGN, which provides virtual palliative care visits for older adults with advanced cancer who are moving from the hospital to a skilled nursing facility. The goal is to see if the program can be delivered successfully and help patients and their…

This study tests whether coating small orthodontic screws (miniscrews) with an antimicrobial substance called K21 can reduce inflammation and improve stability. About 30 people needing at least two screws will participate, with each person receiving one coated screw and one uncoa…

This study looks at whether a supervised exercise program (cardiac rehab) can improve daily function and quality of life in people with Long COVID. Researchers will also study how the heart, lungs, and nervous system are affected. The study needs 30 adults who have had Long COVID…

This study tests a drug called sargramostim, already approved for bone marrow stimulation, in 42 people with mild-to-moderate Alzheimer's disease. Over six months, researchers will check if it is safe and if it helps with thinking and memory. Participants must be 60-85 years old …

This study is testing whether oral cannabis can safely reduce chronic back or neck pain and help people cut down on strong painkillers like opioids. About 157 adults with long-term spine pain will take cannabis capsules or a placebo. The goal is to see if cannabis works as a non-…

This study tests whether Pain Reprocessing Therapy (PRT) helps veterans with chronic back or neck pain more than standard cognitive behavioral therapy (CBT) or usual care. PRT teaches the brain to reinterpret pain signals as less threatening. About 360 veterans will be randomly a…

This study tests whether a one-month treatment combining the drug clemastine fumarate (an allergy medicine) with engineered sounds can improve the ability to hear speech in background noise for people aged 45-65 with age-related central auditory processing disorder. Participants …

This study looks at the safety of fenfluramine, a seizure medicine already approved for children 2 and older with Dravet syndrome, in babies under 2 years old. Dravet syndrome causes hard-to-control seizures starting in the first year of life. The study will enroll 5 children age…

This study tests a digital program called TPA4You that uses a Fitbit to help older adults (50+) who care for a family member with heart failure become more physically active. The goal is to see if the program is practical and can improve daily activity, reduce sitting time, and e…

This study tests whether socks made with a special semiconductor fabric can improve healing and reduce symptoms after an ankle sprain. About 100 adults with ankle injuries will wear either the special socks or regular compression socks and report how they feel. The goal is to see…

This study looks at whether a continuous pain pump delivering numbing medicine (bupivacaine) after a C-section can lower the need for stronger painkillers like opioids. About 100 pregnant adults having C-sections at a special care center will be randomly assigned to get either th…

This study tests whether a telehealth exercise program can reduce cancer-related fatigue in rural breast and prostate cancer survivors. About 134 participants will receive personalized virtual exercise coaching and collect small blood samples at home to track changes. The goal is…

This study tests a new approach called Pain Reprocessing Therapy (PRT) for adults with ongoing knee pain after knee replacement surgery. PRT teaches the brain to reinterpret pain signals, aiming to reduce pain without medication. About 110 participants will be randomly assigned t…

This study is testing a new exercise program for people with knee osteoarthritis. The program uses a special machine to strengthen muscles during the lengthening phase of movement. Researchers want to see if this training helps people climb stairs more smoothly and safely, and re…

This study compares a combination of ibuprofen and acetaminophen against ibuprofen alone or a placebo for managing pain after getting braces. 375 people starting orthodontic treatment will rate their pain on a scale. The goal is to see if the combination provides better pain cont…

This study tests if a short course of steroids given through a vein can reduce swelling in the throat and improve swallowing in people who have recently had a breathing tube. The trial involves 80 adults who are already part of a larger study and have throat swelling seen on a ca…

This study tests whether using mild electrical pulses on the thigh muscle can help people regain strength and movement faster after total knee replacement. Many patients have long-term weakness after surgery, and this treatment is rarely used in rehab. The trial will include abou…

This early-phase study tests whether a single dose of psilocybin, given with therapy, can reduce the intense fear of cancer returning in women who have completed treatment for early-stage breast or ovarian cancer and are now in remission. Twenty participants will receive preparat…

This study aims to make a high-intensity exercise program safe and easy to do at home for people with Parkinson's disease. It also tests a headband that tracks sleep. Sixteen participants in Colorado will try the program and give feedback. The goal is to improve access to exercis…

This study tests whether 12 weekly sessions of parent management training can reduce irritability, anger outbursts, and cranky moods in children aged 10-14. Parents attend the training while children complete assessments. The goal is to see if this approach works in a clinic sett…

This study is testing whether a Spanish-language program called Unstuck and On Target can help children ages 8-11 with autism or ADHD improve their executive functioning skills, like planning and flexibility. About 40 Spanish-speaking families will either join the program right a…

This study tests a procedure called genicular artery embolization (GAE) for people with knee osteoarthritis. The goal is to see if blocking certain blood vessels in the knee can reduce pain and inflammation. About 46 adults with persistent knee pain will get MRIs, questionnaires,…

This study tests whether a special sleep health program helps teens aged 10–19 recover faster from a concussion. About 54 participants will either receive the sleep program or standard sleep advice. The goal is to see if better sleep leads to quicker symptom relief, improved mood…

This study looks at how insulin resistance in type 2 diabetes harms blood flow to the heart and muscles, leading to poor exercise ability. Researchers will test if 15 weeks of exercise training can improve insulin sensitivity and restore blood flow. The study involves 150 sedenta…

This study tests a new imaging device called Electrical Impedance Tomography (EIT) that uses electrodes to create lung pictures without radiation. Researchers will compare EIT images to standard tests in children with chronic lung disease, neuromuscular disease, and healthy contr…

This study works with parents, interpreters, and doctors to create short educational videos in Spanish about key cancer topics. The goal is to help Spanish-speaking caregivers better understand their child's care and feel more supported. The project will test if these videos are …

This study involves 100 adults with advanced lung cancer that has specific genetic changes. Researchers will take small tissue samples before and two weeks after starting targeted therapy to see how the cancer adapts. The goal is to find early signs of drug resistance so future t…

This study collects placenta tissue, umbilical cord blood, and maternal blood from 1250 pregnant women at delivery. Researchers will study these samples to learn how the placenta affects pregnancy complications like preterm birth and diabetes, and how it may program a baby's futu…

This study looks at whether a single dose of equol, a substance made from soy, can improve blood vessel function in postmenopausal women. It includes women with and without chronic kidney disease (CKD). Researchers will measure changes in artery health over a few hours after taki…

This study looks at how different snacks (walnuts or pretzels) change brain activity related to food cravings and fullness during a 12-week weight-loss diet. Researchers will use brain scans to measure responses to food pictures. The goal is to understand which snack might help p…

This study looks at how the autonomic nervous system (which controls heart rate and blood pressure) works in people with Down syndrome. Researchers will measure heart rate, blood pressure, and stress hormones during activities like cold exposure, fear simulations, and exercise. T…

This study looks at whether people with HIV can safely and accurately collect their own blood samples at home using a simple finger prick. The goal is to make it easier to check if HIV medications are at the right levels in the body, without needing to visit a clinic. About 150 a…

This study tests whether a special ultrasound dye can help brain surgeons see the edges of gliomas more clearly during surgery. The goal is to remove as much tumor as possible while sparing healthy brain tissue. About 100 adults having standard brain tumor surgery will receive th…

This study looks at how children and young adults (ages 10 to 25) do after having a joint replaced for reasons other than cancer. Researchers will collect information from medical records and surveys about quality of life. The goal is to understand how these surgeries affect dail…

This study looks at how fat levels (triglycerides) in a pregnant woman's blood affect her baby's body fat. Researchers will have 140 pregnant women with a higher BMI check their triglycerides and glucose at home during pregnancy. After birth, babies will have their total body fat…

This study aims to create a better way for doctors to ask teens and young adults (ages 15-24) who have or survived childhood cancer about sexual health issues. Researchers will test a screening tool to see if it increases communication and satisfaction between patients and provid…

This study looks at whether freezing ovarian tissue can help preserve fertility in people with disorders of sex development who are at high risk of infertility or cancer. Up to 50 participants under 30 will have their tissue frozen before their ovaries are removed. The goal is to…

This study looks at how weight loss affects the fat stored inside your muscles, which can cause inflammation and make it harder for your body to use insulin. Researchers will measure muscle fat, strength, and insulin sensitivity before and after a 12-week diet program. The goal i…

This study is creating a large collection of biological samples (like blood, saliva, and urine) from people with and without Down syndrome, ages 6 months to 89 years. The goal is to help researchers better understand Down syndrome and the health problems that often come with it. …

This study looks at how the right side of the heart works in people with COPD, both at rest and during different levels of exercise. Researchers want to find patterns of heart dysfunction that could help develop better treatments in the future. The study involves 60 adults aged 4…

This study aims to understand how the brain's outer layers handle thinking and decision-making in people with Parkinson's disease. Researchers will insert a thin, high-tech probe into the brain for a short time during awake deep brain stimulation surgery. The study involves 15 ad…

This study works with Spanish-speaking families of children (ages 0-22) with leukemia or lymphoma to understand their experiences and improve communication with their healthcare team. Researchers will interview families to learn about language barriers, satisfaction with care, an…

This study tests a program called Pediatric Medication Therapy Management (pMTM) for children with complex health conditions who take five or more medications. The goal is to see if the program helps find and fix medication-related problems, such as drug interactions or incorrect…

This study tests whether a new imaging technique (shear-wave elastography combined with MRI) can detect scarring or injury in the uterus caused by pelvic radiation. Researchers will enroll 22 women who received pelvic radiation before age 40 and compare their imaging results to h…

This study is not a treatment—it is a long-term research project. Researchers will collect blood, tissue, and health information from 20,000 adults who have cancer or are at risk for it. The goal is to build a large database that helps doctors improve cancer care for everyone in …

This study looks at whether giving extra coaching and support to primary care clinics helps them better identify and manage suicide risk in young people ages 12 to 24. About 360 youth who screen positive for suicide risk will take part. The goal is to see if this coaching leads t…

This study looks at whether freezing testicular tissue is a safe and acceptable way to preserve fertility in male patients of any age who face infertility due to disease or treatments like chemotherapy or radiation. Researchers will track how many eligible patients choose the pro…

This study looks at how the right side of the heart works in people with COPD, both at rest and during exercise. Researchers want to find different patterns of heart strain to help design better treatments in the future. About 60 adults aged 40 and older with COPD will take part.

This study tests whether psilocybin, the active ingredient in magic mushrooms, is safe and tolerable for healthy adults aged 65 to 85. About 40 volunteers will receive the drug and be monitored for side effects. The goal is not to treat any disease, but to gather safety informati…

This study collects blood and tissue samples from 2,000 people being tested or treated for lung cancer. The samples are stored for future research to help detect lung cancer earlier, create better treatments, and explore ways to prevent the disease. No direct treatment is given; …

This study aims to create a mindfulness program for people with metastatic colorectal cancer and their partners to help reduce stress. Researchers will interview 48 patients, partners, and clinicians to understand their needs and preferences. The goal is to design a program that …

This study looks at how a woman's immune system responds to breast cancer, especially if she has been pregnant before. Researchers will follow 800 young women with breast cancer to see if past pregnancy changes how the body fights the tumor. The goal is to better understand these…

This study looks at different ways to help people improve their health habits after filling out a health survey. About 1000 adults who are not active enough and don't eat enough fruits and vegetables will be assigned to one of three follow-up plans or a control group. The goal is…

This study looks at how drinking alcohol and the way couples talk about sex can lead to sexual violence between partners. Researchers will bring 240 couples to a lab, give some alcohol and some a non-alcoholic drink, and observe their reactions. The goal is to understand what inc…

This study involves 60 adults with a below-knee amputation who use either a bone-anchored limb or a standard socket prosthesis. Researchers will test different prosthetic foot stiffness levels while participants perform daily activities like walking. The goal is to understand how…

This study is for teens and young adults aged 12 to 24 who are planning to have weight loss surgery (sleeve gastrectomy). Researchers want to understand how the body changes after surgery and why some people lose more weight than others. For those who haven't lost enough weight 1…

This study looks at 750 adults with rheumatoid arthritis (RA) who are at risk for developing interstitial lung disease (ILD). Researchers use chest CT scans and track changes over 3-5 years to find early signs and risk factors. The goal is to better understand who might develop l…

This study looks at whether exercising in the morning or evening makes a difference in weight loss for people who are overweight. Researchers will track 128 adults over 13 months, measuring weight, body fat, sleep, and eating habits. The goal is to find out if timing your workout…

This study looks at tumor samples from 500 adults with lung or chest cancers to find genetic changes that make targeted therapies stop working. Participants provide tissue from routine biopsies or procedures. The goal is to learn how cancers become resistant, not to test a new tr…

This study follows 400 men with solid tumors to understand how cancer care impacts their ability to work and their overall well-being. It focuses on low-income and Latino men, who often face extra challenges. Researchers will track employment hours, mental health, and financial s…

This study follows 200 babies diagnosed with intra-uterine growth restriction (IUGR) using advanced imaging to track subtle changes in the brain, heart, and placenta over time. Researchers will link these findings to the babies' development after birth and in early childhood. The…

This study looks at whether short-term use of NSAID pain relievers (like ibuprofen) after surgery increases the risk of acute kidney injury in children with mild-to-moderate chronic kidney disease. About 80 children aged 18 months and older will be monitored. The goal is to gathe…

This study tests if a gentle electrical pulse on the ear can improve decision-making and problem-solving. Researchers will include healthy adults, people with mild cognitive impairment, and those with Parkinson's disease. The goal is to see if this safe, non-invasive method can b…

This study uses a new, safe machine called Electrical Impedance Tomography (EIT) to look at children's lungs without harmful radiation. Researchers will compare kids with chronic lung disease to healthy kids, from 2 weeks old to 25 years old. The goal is to learn how lung structu…

This study looks at whether an imbalance in the natural bacteria in your mouth and gut (called dysbiosis) plays a role in head and neck cancer. Researchers will collect stool and saliva samples from 60 adults—some with cancer and some without—to compare their microbiomes. The goa…

This study tests a new ultrasound method that uses tiny bubbles to measure blood flow in the pancreas. The goal is to see if these measurements can help detect type 1 diabetes early. Researchers will compare 50 healthy adults and those recently diagnosed with type 1 diabetes to f…

This study looks at why pregnant women living at high altitude have higher rates of poor fetal growth and preeclampsia. Researchers will collect tissue samples from 84 women having scheduled C-sections in Denver (low altitude) and Summit County (high altitude). By comparing blood…

This study tests whether training ICU staff to keep oxygen levels in a specific range (90-96%) helps patients on breathing machines. Researchers will track how many days patients are free from the ventilator and how often dangerously low oxygen goes unnoticed. The goal is to impr…

This study tests a program called CARES that provides advocacy, resources, education, and support to rural cancer patients. The goal is to see if it helps them start treatment sooner after diagnosis and finish it faster. The study will include 320 adults with solid tumors like lu…

This study looks at the best way to manage Barrett's esophagus with low-grade dysplasia, a condition where the esophagus lining has abnormal but not yet cancerous cells. Researchers will compare two common approaches: regular check-ups with biopsies (surveillance) versus a proced…

This study is testing a 24-week program that combines nutrition counseling, exercise, sleep tips, and stress management for cancer survivors who are overweight. Researchers want to see if the program is practical and helpful for improving sleep quality, reducing stress, and boost…

This study aims to understand why people have different eye movement patterns when searching for something visually. Researchers will measure attention and self-control abilities in 225 adults aged 18-65, then see how these skills relate to eye movements during a computer task. T…

This study looks at how romantic partners who both smoke can help each other quit. Researchers will ask 250 couples to fill out daily surveys for two weeks while trying to quit. The goal is to learn which types of support work best so future programs can help couples quit togethe…

This study looks at sputum and tissue samples from 700 people with or without precancerous changes in the airways. The goal is to find biomarkers—biological clues—that may help detect lung, head and neck, or esophageal cancer earlier. Participants provide samples during routine p…

This study examines whether two common chemotherapy drugs, vincristine and doxorubicin, cause lasting bladder problems in children who have completed cancer treatment. Researchers will measure urine flow, bladder emptying, and specific substances in the urine of 152 children aged…

This study looks at how different behavioral programs that change the way people think about food affect brain activity, eating habits, and body weight. About 228 adults with a BMI of 27 or higher will take part. Researchers will use brain scans and food intake tests to see what …

This study partners with community organizations and trusted local members to improve health research participation among Black, Latino, and Native American communities in Colorado. It focuses on understanding and addressing health issues like mental health, high blood pressure, …

This study is creating a detailed atlas of pre-cancerous spots in the lungs to understand how they turn into cancer. Researchers will collect tissue samples from 240 adults with these spots using a scope down the airway. The goal is to find clues that could help prevent lung canc…

This study looks at whether removing a menstrual cup the right way (by breaking the seal) can cause an IUD to shift or come out. Researchers will measure how often the IUD moves more than 1 cm after cup removal. The goal is to help doctors give better advice to people who use bot…

This study tests a wearable 'smart underwear' device that measures hydrogen sulfide gas produced by gut microbes after eating different diets. About 25 healthy adults will wear the device during the day while following two special diets (high and low cysteine) in random order. Th…

This study looks at whether giving people with type 2 diabetes a Fitbit and sending them personalized text messages can help them become more active and improve their health. About 36 adults who are not very active will wear a Fitbit and answer texts for 12 weeks. The goal is to …