Brain training may soothe Post-Surgery knee pain

NCT ID NCT06800209

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 26 times

Summary

This study tests a new approach called Pain Reprocessing Therapy (PRT) for adults with ongoing knee pain after knee replacement surgery. PRT teaches the brain to reinterpret pain signals, aiming to reduce pain without medication. About 110 participants will be randomly assigned to either PRT (eight weekly video sessions) or usual care, and will complete questionnaires and optional brain activity tests. The goal is to see if PRT provides better pain relief and improves sleep, mood, and daily function compared to standard care.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital for Special Surgery

    RECRUITING

    New York, New York, 10021, United States

    Contact Phone: •••-•••-••••

    Contact

  • University of Colorado Anschutz Medical Campus

    ACTIVE_NOT_RECRUITING

    Aurora, Colorado, 80045, United States

Conditions

Explore the condition pages connected to this study.