Weill Medical College Of Cornell University

This study is testing two different radiation schedules for women with early breast cancer who have had a lumpectomy. One group gets radiation over one week, the other over two weeks with an extra boost to the tumor site. Researchers will compare side effects, breast appearance, …

This study tests whether tirzepatide, a drug used for diabetes and weight loss, is practical and acceptable for postmenopausal women who have had hormone receptor-positive breast cancer and are obese. Thirty participants will take the drug weekly for 24 weeks, with monthly check-…

This study tests whether placing a small balloon in the uterus for 7-10 days after septum removal surgery can prevent internal scar tissue (adhesions). 320 women will be randomly assigned to receive the balloon plus hormones or hormones alone. The main goal is to see if the ballo…

This early-phase study tests a new combination of two drugs that deliver radiation directly to prostate cancer cells. The goal is to find the safest dose that can be given together. About 42 men with advanced prostate cancer that has stopped responding to hormone therapy will tak…

This study tests a method to sort sperm by gender (X or Y chromosome) using a density gradient. The goal is to help couples undergoing IVF or insemination have a baby of a desired sex, for medical or personal reasons. About 2000 couples will take part, and researchers will check …

This study tests a 10-week program to improve heart health in home health aides, who often have poor cardiovascular health. Participants work with a trained peer coach (another home health aide) to learn healthy habits and positive thinking. The program is based on the American H…

This study tests whether a simple technique called double voiding—urinating twice in one bathroom visit—can reduce urinary tract infections (UTIs) in kidney transplant recipients. UTIs are common after transplant and can lead to serious complications. The trial will compare doubl…

This study tests whether a drug called leronlimab is safe for people with mild Alzheimer's or mild cognitive impairment. Twenty volunteers over age 50 will receive weekly injections for 12 weeks. Researchers will use brain scans and blood tests to see if the drug lowers brain inf…

This study tests whether a newer surgical method called Kono-S anastomosis can better prevent Crohn's disease from returning after bowel surgery compared to the standard side-to-side technique. About 600 adults with Crohn's disease needing bowel resection will be randomly assigne…

This small pilot study tests whether cutting a fibrous strand at the end of the spinal cord (filum terminale) can relieve symptoms of occult tethered cord syndrome better than medical management alone. Twenty people aged 2 to 80 who have not improved with standard care will be ra…

This study tests different combinations of immunotherapy drugs (with or without radiation) in 24 people with colorectal cancer that has spread to the liver and who are scheduled for surgery. The goal is to see if these treatments change the immune environment inside the liver tum…

This study tests whether community health workers can help women in urban slums of India get screened for type 2 diabetes after having gestational diabetes. 330 women will either receive home-based testing or a referral to a clinic, plus diabetes education. A smaller part of the …

This study tests a program called I-TRANSFER-HF for people with heart failure who need home care after leaving the hospital. The program combines early nurse visits at home with quick follow-up doctor appointments to prevent patients from returning to the hospital within 30 days.…

This phase 2 trial tests whether combining the immunotherapy drug cemiplimab with either chemotherapy or targeted radiation (SBRT) before surgery can eliminate or shrink non-small cell lung cancer more effectively. About 112 people with stage IB to III (N2) lung cancer will recei…

This phase 2 study tests a new approach for people with advanced stomach, esophageal, or gastroesophageal junction cancer that is either PD-L1-negative or has stopped responding to immunotherapy. Participants receive injections of a cancer-killing virus (OBP-301) directly into th…

This study looks at a surgery called selective laryngeal reinnervation for people whose vocal cords are paralyzed on both sides, making it hard to breathe. Researchers will track 15 adults aged 18 to 70 to see if the surgery improves breathing symptoms and lung function. The goal…

This study is for men with advanced prostate cancer that has spread and is no longer controlled by standard hormone therapy. It tests whether adding a targeted radiation drug (225Ac-J591) to immunotherapy (pembrolizumab) and an androgen-receptor inhibitor works better than the im…

This study tests a combination of two drugs—pembrolizumab (an immunotherapy that helps the immune system fight cancer) and lutetium Lu 177 dotatate (a radioactive drug that kills cancer cells)—in 18 adults with Merkel cell carcinoma. The goal is to see if the combination can shri…

This study compares a standard robot-assisted prostate removal surgery to a newer, pelvic fascia-sparing approach that aims to preserve nerves and support structures. Researchers will enroll 600 men with localized prostate cancer to see if the new technique offers similar cancer …

This trial tests whether using two or more arterial grafts during heart bypass surgery is better than using just one. About 4,300 patients will be randomly assigned to receive either a single arterial graft or multiple arterial grafts. The goal is to see if multiple grafts reduce…

This study tests a new way to help people with HIV in rural Uganda. Traditional healers will be trained to offer HIV testing, counseling, and support to take medication regularly. The goal is to see if this extra help, alongside regular clinic care, can help more people achieve a…

This early-stage trial tests whether injections of special cells (E-CEL UVEC) can safely heal chronic anal fissures that haven't responded to other treatments. Twenty adults with long-lasting anal fissures will receive the cell injection directly into the fissure. The study prima…

This early-stage trial tests a gene therapy called AAVrh.10hFXN for heart problems caused by Friedreich's ataxia, a rare genetic disease. The therapy delivers a working copy of the frataxin gene to help heart cells function better. 25 people aged 12 to 50 with heart involvement w…

This study is testing whether using multiple arteries during coronary bypass surgery improves outcomes for women compared to using just one artery. About 2,300 women will be randomly assigned to receive either a single arterial graft or multiple arterial grafts. The goal is to se…

This study is for people with metastatic breast cancer that has spread to the brain, with at least two brain tumors. Participants receive an immunotherapy drug called pembrolizumab every three weeks, plus a precise, one-time radiation treatment to just one of the brain tumors. Th…

This study is testing whether inviting friends, family, or coworkers to join a weight-loss program helps Black or Hispanic adults with obesity lose more weight. The program focuses on improving communication and problem-solving around eating and activity. Researchers will see if …

This study tests the drug luspatercept in 50 adults with clonal cytopenias of uncertain significance (CCUS), a condition where low blood cell counts increase the risk of developing blood cancers like leukemia. Participants receive injections every three weeks for up to 48 weeks. …

This study tests whether coaching and support from community health workers, delivered by phone or video, can help people with dangerously high blood pressure avoid serious heart problems. Over 3,600 adults who came to the emergency room with very high blood pressure will be rand…

This early-stage study tests a gene therapy for people with alpha-1 antitrypsin deficiency, a condition that can damage the lungs. The treatment is given once through a vein and aims to produce a special protein that protects the lungs. Researchers will check safety and measure p…

This study tests if eating only during an 8-hour window each day, along with a healthy diet and exercise, can reduce liver fat in people with non-alcoholic fatty liver disease. About 40 adults will be split into two groups: one follows the time-restricted eating plan plus standar…

This study looks at whether women who had breast cancer come back after earlier lumpectomy and radiation can avoid a mastectomy by getting a second round of targeted radiation. About 120 women with small, isolated recurrences will receive partial or whole breast radiation dependi…

This phase 2 trial is testing a new approach for post-menopausal women with HR+HER2- breast cancer. Participants receive standard hormone therapy plus focal radiation, and some also get the immunotherapy drug pembrolizumab and an immune booster (CDX-301). The goal is to see if th…

This study tests whether a single, lower dose of radiation can safely reduce episodes of ventricular tachycardia (a dangerous fast heart rhythm) in people who haven't been helped by standard treatments. About 40 adults with structural heart disease and recurrent VT will receive e…

This phase II trial is testing whether using a special PET/MR scan (PSMA) to guide radiation therapy can improve outcomes for men with high-risk prostate cancer. Fifty participants will receive targeted radiation boosts to areas identified by the scan. The main goal is to see if …

This study compares two blood thinner strategies in 700 people with chronic heart disease who are having bypass surgery. One group takes ticagrelor plus low-dose aspirin for one month, then aspirin alone; the other takes only low-dose aspirin. The goal is to see if the short dual…

This Phase 2 trial tests whether adding targeted radiation (SBRT) to standard hormone therapy and a CDK4/6 inhibitor can help women with metastatic HR+ HER2- breast cancer live longer without their disease worsening. About 102 participants will be randomly assigned to receive eit…

This study tests whether treating eggs and sperm before fertilization can help people who have had complete failure with standard IVF or one prior ICSI cycle. Researchers will measure fertilization rates and embryo development. The goal is to improve chances of pregnancy for thos…

This study is tracking 20 adults aged 18-65 with colorectal cancer that has spread only to the liver and cannot be surgically removed. Participants will receive a liver transplant, and researchers will monitor cancer recurrence and survival rates. The goal is to see if a transpla…

This early-stage trial tests a new drug called TVB-2640 combined with the standard drug enzalutamide (Xtandi) in 30 men whose prostate cancer has spread and stopped responding to hormone therapy. The main goal is to find the safest dose of TVB-2640 when used with enzalutamide and…

This early-phase trial tests whether injecting special cells from human umbilical veins (E-CEL UVEC) can safely help heal simple anal fistulas after surgery. The study involves 39 adults who are already scheduled for fistulotomy. Researchers will monitor for side effects over two…

This early-stage trial tests whether the beta-blocker propranolol can stimulate heart muscle cell growth in infants born with Tetralogy of Fallot, a serious heart defect. Forty infants under 60 days old will receive propranolol, and researchers will measure new heart muscle cells…

This study looks at whether using a biosynthetic mesh during robotic anti-reflux surgery can lower the chance that a hiatal hernia returns. About 200 adults with GERD who are already scheduled for surgery will be randomly assigned to receive either the standard repair or repair w…

This study tests a vaccine called dAd5GNE in 150 people who are dependent on cocaine. The vaccine is designed to train the immune system to attack cocaine, preventing it from reaching the brain and causing a high. The main goal is to check if the vaccine is safe, while also measu…

This phase 2 trial is testing whether adding the drug polatuzumab vedotin to standard chemotherapy can improve remission rates in people with Richter's transformation, an aggressive lymphoma that can develop from chronic lymphocytic leukemia (CLL). About 20 adults with confirmed …

This study tests whether training Christian and Muslim religious leaders to teach their communities about blood pressure can lower average blood pressure. Researchers will compare communities where leaders receive training to those where they do not. About 24,000 adults aged 35 a…

This study compares two common heart procedures—bypass surgery (CABG) and stenting (PCI)—in 600 minority patients with coronary artery disease. The goal is to see which approach leads to better survival and quality of life. Participants will be followed over time to track outcome…

This study is testing whether adding the antifungal drug fluconazole to standard IL-23 therapy helps people with mild to moderate Crohn's disease. About 120 adults will be randomly assigned to receive either fluconazole or a placebo alongside their usual treatment. The main goal …

This study enrolls 600 women with blocked heart arteries to compare two common procedures: bypass surgery (CABG) and stenting (PCI). The goal is to see which one leads to better survival and quality of life. Participants will be followed over time to measure outcomes.

This study is testing whether a special type of PET/CT scan (PSMA-PET CT) can accurately detect aggressive prostate cancer in men who are on active surveillance (watchful waiting). Researchers will scan 200 men with low- or favorable intermediate-risk prostate cancer at the start…

This pilot study tests whether a radioactive tracer called [Cu64]DOTATATE, combined with a handheld gamma probe, can help surgeons find meningioma tumors during surgery. Twenty adults with suspected or recurrent meningioma will receive the tracer before surgery, and the probe wil…

This study aims to improve how doctors find and treat breast cancer that has spread to the brain. Twenty adults with ER-positive breast cancer and brain tumors will get an extra PET scan (FES PET/CT) before their standard radiation planning. Researchers will compare this scan wit…

This study tests whether a special PET/MRI scan using a radioactive tracer called Ga68-DOTATATE can better detect certain brain tumors (like meningioma) and tell them apart from changes caused by past treatments. About 200 adults with these tumors will get the scan alongside stan…

This study tests a special MRI technique to see if it can tell the difference between normal and painful jaw muscles in people with masticatory myofascial pain syndrome. Researchers will scan the jaw muscles of 90 adults and compare the results. The goal is to find a better way t…

This study tests a science curriculum called CARES4You, taught by regular teachers in New York City middle schools. The lessons cover cancer risk, genetics, and healthy choices. Researchers will compare students who get the program to those who don't, looking at whether they inte…

This study tests whether playing a video game called 'No Baby No' can help teens aged 15-20 use birth control more often and avoid unplanned pregnancy. About 850 teens will either play the game or do a different activity, and researchers will track their birth control use and pre…

This study aims to find helpful treatments for healthcare workers suffering from PTSD and distress due to work-related trauma. In the first phase, 120 participants will be randomly assigned to either a music-listening or a writing session over two weeks. Those who still have PTSD…

This study compares three devices used for fat grafting in breast reconstruction after mastectomy. Researchers want to see which method leads to better fat retention and patient satisfaction. About 135 women who have had breast surgery will take part, and their results will be me…

This study tests whether playing an immersive virtual reality game during painful burn treatments (like dressing changes) can reduce pain and the need for opioid painkillers. Fifty adult burn patients will be randomly assigned to receive either standard care alone or standard car…

This study tests a wearable device that vibrates leg muscles to reduce spasticity (stiffness) and improve walking. Twenty-five people with spasticity from a neurological condition will use the device for 15–60 minutes in the lab and at home. Researchers will measure muscle activi…

This pilot study is testing a 12-session virtual therapy that combines two proven treatments—one for PTSD and one for chronic pain—into a single program. Researchers want to see if this integrated approach is feasible and acceptable for adults who suffer from both conditions. The…

This study tests whether joining a virtual support group can help reduce anxiety in people who have had Takotsubo syndrome, also known as 'broken heart syndrome.' Participants meet online every other week for group therapy and education. The goal is to see if this support lowers …

This study tests two types of spiritual care for people with advanced cancer. Researchers want to see if these programs improve spiritual well-being and reduce hospital visits. About 288 patients from religious communities will take part.

This study tests a 10-week program called RISE-HP for people with hypersensitivity pneumonitis (HP), a lung condition that can cause anxiety, depression, and poor quality of life. Participants work one-on-one with a trained peer coach (someone who also has HP) to learn coping ski…

This study compares a standard mobile cognitive behavioral therapy (CBT) program to a personalized version that teaches skills faster. About 100 adults aged 18-25 with anxiety, depression, or bipolar disorder will use the Maya app for 20 minutes, twice a week, for six weeks. The …

This study is testing a mobile app called MAYA that teaches cognitive behavioral therapy (CBT) skills to help older adults manage anxiety and depression. About 60 participants aged 40 and older with an anxiety or depressive disorder will use the app for at least 20 minutes, twice…

This study compares two types of nerve blocks (PENG vs femoral) to see which provides better pain relief for people with hip fractures. About 352 adults with a hip fracture will receive one of the two blocks, depending on the month they come to the hospital. Researchers will meas…

This study tests whether a digital program on an iPad, combined with learning thinking strategies, can improve mood and mental skills in people who have had a stroke. The study will include 70 adults who had a first stroke at least 6 months ago and now have depression and trouble…

This study tests a special bracelet that vibrates gently whenever it senses you biting your nails. Ten adults with nail-biting problems will wear the bracelet for 12 weeks and track their habits using a phone app. The goal is to see if the vibration helps reduce nail biting and i…

This study tests a program called PATH-Pain in 100 older adults (60+) who have mild cognitive impairment or early Alzheimer's, along with chronic pain and depression. The program teaches problem-solving and uses memory aids like checklists and a tablet app to help manage emotions…

This study compares two types of talk therapy for PTSD caused by military sexual trauma: exposure therapy and interpersonal therapy. Researchers want to see if interpersonal therapy works just as well as exposure therapy, which could give survivors more options. The trial will en…

This study tests whether a 9-week therapy called Engage & Connect can improve brain function related to social reward and reduce suicidal thoughts in older adults with depression. Researchers will use brain scans to measure changes in key brain networks. The study involves 128 pe…

This study is testing a mobile app called MAYA that provides cognitive behavioral therapy (CBT) to help adults who have had a stroke manage anxiety and depression. About 10 participants aged 40-79 will use the app and provide feedback on how easy and helpful it is. The goal is to…

This pilot study tests two types of spiritual care for Black patients with advanced cancer. Researchers want to see if these interventions improve spiritual well-being and readiness to make future care plans. The study will enroll 64 participants from outpatient clinics to see if…

This study tests whether a procedure called ovarian and pelvic vein embolization can reduce chronic pelvic pain in women with pelvic varicose veins. Forty women with severe pain lasting over six months will be randomly assigned to either the embolization procedure or a diagnostic…

This pilot study tests whether a mobile app called Maya is practical and liked by pregnant and postpartum individuals who are struggling with mood, anxiety, or stress. The app teaches cognitive behavioral skills through 12 modules. Researchers will ask 75 participants for feedbac…

This study tests a new, faster version of a brain stimulation treatment called TMS for people with depression or OCD. Instead of daily sessions for weeks, participants get 10 hours of TMS each day for just 5 days. The goal is to see if this quick approach can improve symptoms and…

This study tests if a gentle electrical current applied to the forehead at home can reduce severe tiredness after a stroke. Researchers will enroll 24 people who are at least 3 months past their stroke and have significant fatigue. Participants will use a headset device daily, wi…

This study tests whether using a brain scan (fMRI) to guide magnetic stimulation (rTMS) can better treat depression that hasn't improved with medication. About 348 adults aged 22-65 with major depression will receive rTMS, and researchers will track changes in depression scores. …

This study tests whether giving acetaminophen (Tylenol) and ketorolac (Toradol) to children on ventilators can better control pain and reduce the need for strong opioids. About 644 children aged 2 months to 17 years with acute respiratory failure will be randomly assigned to rece…

This study looks at whether giving a TAP block—a numbing injection in the belly wall—before surgery works better than giving it after surgery to control pain and reduce opioid use. Researchers will track pain scores and opioid amounts in 150 adults having elective abdominal or we…

This study is testing an 8-week group program that teaches meditation, breathing, and relaxation skills to help medical graduate students manage mood symptoms like anxiety and depression. About 60 students with mild-to-moderate symptoms will participate. The goal is to see if the…

This study tests whether having a peer coach—someone who also has rheumatoid arthritis (RA)—can lower anxiety and depression in adults with RA. Participants meet with their coach weekly for 9 weeks and complete surveys. The trial compares this to general health coaching from peop…

This study tests whether an 8-week health education program called Living Healthy, plus support from a trained peer coach (another home health aide), can improve mood and well-being in home health aides. 100 aides with mild depression, stress, or loneliness will be randomly assig…

This study tests a short therapy program called EMPOWER for family members who make decisions for critically ill patients in the ICU. The therapy includes breathing exercises, mindfulness, and coping techniques delivered by a mental health professional. Researchers will compare i…

This study tests a mobile app called WellPATH-PREVENT for adults aged 50-90 who were recently hospitalized for suicidal thoughts or a suicide attempt. The app teaches emotion regulation skills to help reduce suicide risk. Researchers will measure changes in brain activity, self-r…

This pilot study tests whether a device called IVS3 is tolerable and easy to use for arm recovery in people who had a stroke at least 6 months ago. The device uses mirrored video to create the illusion that the affected arm is moving. Researchers will track how many sessions part…

This study tests whether virtual reality (VR) can help healthcare workers and COVID-19 patients with posttraumatic stress disorder (PTSD). Participants will use VR headsets during 10 therapy sessions over 5 weeks to safely revisit and overcome traumatic memories. The goal is to s…

This study tests whether taking calcium carbonate (a common calcium supplement) every 4 hours during labor can safely improve contractions and reduce the need for high doses of synthetic oxytocin. The trial will enroll 60 first-time mothers who are being induced or need help with…

This study tests a new type of talk therapy called Engage & Connect for mothers with postpartum depression. The therapy focuses on helping moms plan and do rewarding social activities to reduce feelings of isolation. Sixty participants will receive either this new therapy or a st…

This pilot study tests whether the dietary supplement L-Phenylalanine can change the levels of fungi (like Candida) and a specific metabolite in the gut of 20 healthy adults. Researchers will measure these changes in stool, swabs, and blood samples over time. The goal is to bette…

This study explores whether adenosine, a drug that affects heart rhythm, can help identify the mechanism behind premature ventricular contractions (PVCs). About 100 adults scheduled for a standard heart procedure will receive adenosine or verapamil to see how their extra beats re…

This study compares a smartphone chatbot to usual care for collecting family history and identifying women at high risk for hereditary cancer syndromes. Participants are English-speaking gynecology patients aged 18 and older who have not had prior genetic testing. The goal is to …

This pilot study will test a decision support tool called COAST, available as a booklet and website, designed to help people with stage IV breast cancer have better conversations with their doctors about treatment options. About 100 patients will use the tool and fill out surveys…

This study is looking at how short-course radiation therapy (5 days of treatment) affects the immune system in people with rectal cancer. Researchers will collect blood, stool, and tumor tissue samples before, during, and after radiation to study these changes. The goal is to bet…

This study aims to measure how well infants' hearts can make new muscle cells, especially in those with a heart condition called Tetralogy of Fallot. Researchers will use a special imaging technique on heart tissue that is normally removed and thrown away during surgery. The goal…

This study aims to develop a better way to measure how the brain uses sugar (glucose) for energy. Researchers will use advanced MRI-like scans at 3 or 7 Tesla strength in 20 healthy volunteers and people with Glut1 deficiency, a rare condition that affects brain fuel. Participant…

This pilot study is testing whether letting people eat their regular diet right after colon surgery is safe and can improve their quality of life. Ten adults scheduled for colon removal will be followed for 30 days. The goal is to see if simplifying diet advice is feasible and do…

This study explores whether the gut's nervous system can reveal early signs of Parkinson's disease. Researchers will analyze gut tissue and microbiome samples from 60 people aged 45-75 during routine colonoscopies. The goal is to find biomarkers that reflect brain changes, not to…

This study collects information from medical records and patient visits to see how well endoscopic bariatric therapies (EBTs) work for weight loss and if they are safe. It includes adults who have had or plan to have an EBT within six months. The goal is to track weight changes a…

This study looks at whether digital devices like smartwatches and blood pressure cuffs can help detect high blood pressure and related pregnancy problems in refugee women. About 75 pregnant refugee women will use these tools at home and complete surveys. The goal is to see if thi…

This study is testing a tool called Transit-Time Flow Measurement (TTFM) that uses sound waves during heart bypass surgery to check blood flow through the new blood vessels. The goal is to see if using this tool helps the grafts stay open longer. About 1242 adults having their fi…

This study tracks children and adults with genetic developmental and epileptic encephalopathy (DEE) over time. It does not test any treatment but collects information on development, seizures, and quality of life through in-person visits, virtual visits, or online surveys. The go…

This study tests a training program called the Pain Identification and Communication Toolkit (PICT) for family caregivers of people with Alzheimer's disease or related dementias. The program teaches caregivers how to spot signs of pain and talk about it with doctors. Researchers …

This study uses cardiac MRI and other tests to examine heart and lung function in 510 COVID-19 survivors who had symptoms like shortness of breath or cough. The goal is to find out why some people have lasting cardiopulmonary problems after COVID-19. Participants will undergo ima…

This study is testing how long two different volumes of a common numbing medicine (lidocaine with epinephrine) keep the skin numb during dermatologic surgery. Researchers will inject either 0.5 ml or 1.0 ml into the side of the nose in 35 adults and check every 15 minutes when fe…

This study tests whether connecting ambulances carrying seriously ill children to a remote doctor via a simple audio-video device improves care. Researchers in Karachi, Pakistan will compare health outcomes for 900 children who either receive a telemedicine call during transport …

This study explores whether offering genetic testing for inherited cancer risk (like BRCA1/2) during routine pregnancy or fertility care is practical and acceptable to patients. Researchers will enroll 550 people receiving prenatal or preconception care at Weill Cornell Medicine.…

This study is testing whether an artificial intelligence tool can analyze 3D ultrasound images of the ovaries to better predict how well a woman will respond to fertility treatments like IVF. Researchers will enroll about 4,000 patients undergoing ovarian stimulation. The goal is…

This study is collecting information from 200 men who have had or will have focal therapy for prostate cancer. Focal therapy uses targeted methods like freezing (cryotherapy) or ultrasound (HIFU) to treat only the cancerous part of the prostate. The goal is to understand how thes…

This study is creating a 'live biobank' by collecting tumor samples from 400 breast cancer patients at key moments: diagnosis, surgery, and if the cancer returns or spreads. Researchers will grow mini-tumors from these samples and analyze their genes and immune cells. The goal is…

This study collects leftover brain and spinal cord tumor tissue from 500 patients during surgery or autopsy. Researchers will use the tissue to create cell lines and models to test how different drugs work. The goal is to better understand these tumors and find new ways to treat …

This study is looking at ways to freeze ovarian tissue so that people who might lose their fertility due to cancer treatment or ovary removal can still have a genetically related child later. Researchers are working on improving the freezing, thawing, and maturing of eggs from th…

This study collects blood, airway, and urine samples from 2,000 healthy volunteers and people with lung diseases like COPD and pulmonary fibrosis. Researchers will compare samples to establish normal ranges and learn how genes change in lung disease. The goal is to better underst…

This study is testing a special shoe called NUSHU that has sensors to measure how people with Parkinson's disease walk and keep their balance. The shoe can also give small vibrations to possibly help with walking problems. Researchers will compare results from people with early, …

This study looks at whether a web-based tool called CONSYDER can help young women (ages 18-44) newly diagnosed with early-stage breast cancer make more informed decisions about their surgery. Participants will use the tool and complete surveys before and after their surgical cons…

This study collects tissue samples, medical data, and family histories from over 1,100 people being screened for colorectal or endometrial cancer. Researchers hope to discover new genes and mechanisms that increase cancer risk, especially in hereditary cancer syndromes. The goal …