Promising combo tackles Hard-to-Treat prostate cancer
NCT ID NCT04946370
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 31 times
Summary
This study tests whether adding a radiation drug (225Ac-J591) to standard immunotherapy (pembrolizumab) and hormone therapy can better control advanced prostate cancer that has spread and stopped responding to treatment. About 52 men with this type of cancer will receive either the triple combination or the standard two-drug regimen. The goal is to see if the new combination shrinks tumors, lowers PSA levels, and improves survival, while monitoring side effects.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Columbia University Irving Cancer Center
RECRUITINGNew York, New York, 10032, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Dana-Farber Cancer Institute
NOT_YET_RECRUITINGBoston, Massachusetts, 02215, United States
Contact
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New York Presbyterian/Brooklyn Methodist Hospital
RECRUITINGBrooklyn, New York, 11215, United States
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New York Presbyterian/Weill Cornell Medical Center
RECRUITINGNew York, New York, 10021, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Conditions
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