Spinal cord snip: could a simple surgery ease hidden tethered cord symptoms?

NCT ID NCT05163899

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This small pilot study tests whether cutting a fibrous strand at the end of the spinal cord (filum terminale) can relieve symptoms of occult tethered cord syndrome better than medical management alone. Twenty people aged 2 to 80 who have not improved with standard care will be randomly assigned to surgery or continued medical treatment. The study measures changes in a combined symptom score covering nerve, bladder, bowel, and orthopedic issues.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
surgical release of the filum terminale (a fibrous strand at the end of the spinal cord)
What this could lead to
If it works, this could point toward a surgical treatment option for people with occult tethered cord syndrome who haven't improved with medical management.
What could go wrong
This is a very small pilot study with only 20 participants, so results may not apply to everyone. Surgery on the spine carries risks like infection, nerve damage, or no symptom improvement.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Weill Cornell Medicine

    RECRUITING

    New York, New York, 10065, United States

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