Spinal cord snip: could a simple surgery ease hidden tethered cord symptoms?

NCT ID NCT05163899

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This small pilot study tests whether cutting a fibrous strand at the end of the spinal cord (filum terminale) can relieve symptoms of occult tethered cord syndrome better than medical management alone. Twenty people aged 2 to 80 who have not improved with standard care will be randomly assigned to surgery or continued medical treatment. The study measures changes in a combined symptom score covering nerve, bladder, bowel, and orthopedic issues.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

surgical release of the filum terminale (a fibrous strand at the end of the spinal cord)

What this could lead to

If it works, this could point toward a surgical treatment option for people with occult tethered cord syndrome who haven't improved with medical management.

What could go wrong

This is a very small pilot study with only 20 participants, so results may not apply to everyone. Surgery on the spine carries risks like infection, nerve damage, or no symptom improvement.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neural tube defect primary tethered cord syndrome spina bifida occulta spinal cord injury tethered spinal cord syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Weill Cornell Medicine

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact