New combo therapy targets aggressive leukemia transformation
NCT ID NCT04679012
First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 27 times
Summary
This study tests a drug called polatuzumab vedotin combined with standard chemotherapy for people whose chronic lymphocytic leukemia has turned into a more aggressive form called Richter's transformation. About 20 adults will receive up to six treatment cycles and be monitored for side effects and how well the cancer responds. The goal is to see if this combination can control the disease better than current options.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Columbia University Medical Center
RECRUITINGNew York, New York, 10032, United States
Contact
Contact
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Mount Sinai- Icahn School of Medicine
RECRUITINGNew York, New York, 10029, United States
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Contact
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Ohio state University
RECRUITINGColumbus, Ohio, 43210, United States
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Contact
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Weill Cornell Medicine
RECRUITINGNew York, New York, 10065, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.