RICHTER SYNDROME
Clinical trials for RICHTER SYNDROME explained in plain language.
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New hope for aggressive cancer: trial tests powerful drug combo
Disease control Recruiting nowThis study is testing whether adding a new drug called glofitamab to standard chemotherapy (R-CHOP) works better for people with a rare and aggressive cancer called Richter syndrome. The trial will enroll 40 adults who have not yet received treatment for this condition. The main …
Matched conditions: RICHTER SYNDROME
Phase: PHASE2 • Sponsor: French Innovative Leukemia Organisation • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New hope for aggressive blood cancer complication
Disease control Recruiting nowThis study is testing whether adding a targeted drug called polatuzumab vedotin to standard chemotherapy works better for people with Richter's transformation, a serious complication where chronic lymphocytic leukemia turns into a more aggressive lymphoma. About 20 adults with th…
Matched conditions: RICHTER SYNDROME
Phase: PHASE2 • Sponsor: Weill Medical College of Cornell University • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Triple-Threat attack on rare, deadly blood cancer
Disease control Recruiting nowThis study is testing a new combination of three cancer drugs for patients with Richter's transformation, a rare and aggressive form of blood cancer that develops from chronic lymphocytic leukemia (CLL). The treatment combines a personalized cell therapy (made from the patient's …
Matched conditions: RICHTER SYNDROME
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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First-in-Human trial tests new drug duo for aggressive blood cancer
Disease control Recruiting nowThis early-stage study is testing a new combination of two drugs, zanubrutinib and odronextamab, for patients with Richter's transformation, a fast-growing lymphoma. The main goal is to find a safe dose and understand the side effects. Researchers will also check if the treatment…
Matched conditions: RICHTER SYNDROME
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Three-Pronged attack on rare, aggressive blood cancer
Disease control Recruiting nowThis study is testing a combination of three drugs—acalabrutinib, venetoclax, and durvalumab—to see if they can help control a rare and aggressive cancer called Richter transformation. Richter transformation occurs when a slower-growing blood cancer (CLL) suddenly changes into a …
Matched conditions: RICHTER SYNDROME
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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New hope for aggressive lymphoma: trial tests Dual-Attack therapy
Disease control Recruiting nowThis study is testing a new combination of two drugs, nemtabrutinib and pembrolizumab, for patients with Richter transformation, a fast-growing type of lymphoma. The goal is to see if using these drugs together is safe and can shrink or control the cancer. The trial will enroll a…
Matched conditions: RICHTER SYNDROME
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Mar 10, 2026 12:52 UTC