New drug combo targets aggressive blood cancer in early trial
NCT ID NCT06735664
First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 30 times
Summary
This early-phase study tests whether combining two drugs—zanubrutinib and odronextamab—is safe and effective for people with Richter's transformation, an aggressive lymphoma that can develop from chronic lymphocytic leukemia. The trial enrolls 23 adults whose cancer has come back or not responded to prior treatment. The goal is to find the best dose and measure how well the combination shrinks tumors.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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City of Hope Medical Center
RECRUITINGDuarte, California, 91010, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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