TRANSFORMED CHRONIC LYMPHOCYTIC LEUKEMIA TO DIFFUSE LARGE B-CELL LYMPHOMA
Clinical trials for TRANSFORMED CHRONIC LYMPHOCYTIC LEUKEMIA TO DIFFUSE LARGE B-CELL LYMPHOMA explained in plain language.
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New combo therapy targets tough lymphoma
Disease control Recruiting nowThis study tests a combination of two treatments—zanubrutinib (a targeted drug) and lisocabtagene maraleucel (a CAR T-cell therapy)—for people with Richter's syndrome, an aggressive lymphoma that has returned or not responded to prior treatment. About 24 participants will receive…
Matched conditions: TRANSFORMED CHRONIC LYMPHOCYTIC LEUKEMIA TO DIFFUSE LARGE B-CELL LYMPHOMA
Phase: PHASE2 • Sponsor: Aseel Alsouqi • Aim: Disease control
Last updated May 17, 2026 04:17 UTC
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New drug combo targets aggressive blood cancer in early trial
Disease control Recruiting nowThis early-phase study tests whether combining two drugs—zanubrutinib and odronextamab—is safe and effective for people with Richter's transformation, an aggressive lymphoma that can develop from chronic lymphocytic leukemia. The trial enrolls 23 adults whose cancer has come back…
Matched conditions: TRANSFORMED CHRONIC LYMPHOCYTIC LEUKEMIA TO DIFFUSE LARGE B-CELL LYMPHOMA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 14, 2026 12:04 UTC