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New therapy aims to tackle PTSD and chronic pain in one go

NCT ID NCT07225049

Symptom relief Sponsor: Weill Medical College of Cornell University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study is testing a 12-session virtual therapy that combines two proven treatments—one for PTSD and one for chronic pain—into a single program. Researchers want to see if this integrated approach is feasible and acceptable for adults who suffer from both conditions. The study will enroll 20 participants and measure things like session attendance, satisfaction, and changes in symptoms.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Integrated psychotherapy combining Prolonged Exposure and Cognitive Behavioral Therapy for Chronic Pain
What this could lead to
If this pilot succeeds, it could point toward a more effective and efficient way to treat PTSD and chronic pain together, potentially improving symptoms and quality of life.
What could go wrong
This is a very small, early pilot study with only 20 participants and no comparison group. It is designed to test feasibility, not effectiveness, so results may not generalize.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18 years or older * English-speaking * Currently meets criteria for PTSD, assessed by the CAPS-5 (any trauma type) - Chronic pain, assessed by greater than or equal to 4 on a scale of 0-10 pain severity over the past 3 months * Medically stable at the time of study enrollment (chronic illness and disability does not prevent attendance of outpatient therapy sessions) * Stable on psychotropic medication for past 60 days * Agreed to not change current medication or pain-related treatments over the course of the study unless medically necessary * Must be located in the state of New York for virtual assessments and treatment sessions Exclusion Criteria: * Lifetime diagnosis of schizophrenia, other psychotic disorder, or bipolar I disorder * Participation in concurrent evidence-based psychological treatment for PTSD or chronic pain during the past 3 months * Participants must not participate in an evidence-based psychological treatment for either PTSD or pain during the course of the study. * Moderate or severe substance use in the past 90 days * Cognitive impairment to the degree that the patient cannot provide informed consent or fill out assessment measures * Participants who in the PI's judgement pose a current homicidal or suicidal risk

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic pain PTSD

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Weill Cornell Medicine

    RECRUITING

    New York, New York, 10065, United States

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