Could mindfulness audio recordings unlock relief for chronic jaw pain?
NCT ID NCT06582134
First seen Sep 02, 2026 · Last updated Sep 03, 2026 · Updated 1 time
Summary
This trial tests whether brief mindfulness-based audio recordings can ease pain and improve jaw function in university students with painful temporomandibular disorders (TMD), a common cause of chronic jaw pain. Participants listen to the recordings three times a week for three months, and researchers compare their pain, jaw function, psychological distress, and quality of life against a control group. The study involves 127 students and includes four clinic visits over the three-month period.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Brief mindfulness-based intervention delivered via audio recordings
- What this could lead to
- If it works, this could offer a simple, low-cost way for students to manage chronic jaw pain and related stress at home.
- What could go wrong
- The trial is small and early, and the benefit may be modest or no better than a placebo. Listening to recordings requires consistent effort over three months.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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127 people
The number who actually took part.
- Started
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Jan 2024
- Finished
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Sep 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 30 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Students attending Universiti Malaya * Able to read and understand English. * Willing and able to give informed consent. * Score 3 and above on the TMD-PS, for at least 3 months. Exclusion Criteria: * Hearing impairment. * Currently on psychiatric follow up and/or taking psychotropic prescriptions (antidepressants, anti-anxiety medications, stimulants, antipsychotics, and mood stabilizers). * Experience with activities similar to the intervention such as meditation, yoga or tai chi. * Currently practicing some form of mindfulness meditation. * History of orofacial trauma, craniofacial pathology, and previous orofacial surgeries (including orthognathic and TMJ) * Systemic rheumatic, neurologic/neuropathic, endocrine (e.g., diabetes mellitus) or immune / autoimmune diseases or widespread pain or being treated with immunosuppressant drugs * Non-TMD orofacial pain disorders * Radiation treatment to head and neck. * Use of narcotic pain medication, muscle relaxants or steroid therapy unless discontinued 1 week before enrolment to study * Use of nonsteroidal anti-inflammatory medications unless the medication(s) were discontinued for 3 days prior to enrolment (use of acetaminophen is allowed as a rescue drug) * Currently on antibiotics or taken antibiotics within the last 2 weeks prior to start of study * Currently pregnant or lactating women
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Oral Medicine Clinic, Faculty of Dentisty, Universiti Malaya
Kuala Lumpur, Kuala Lumpur, 50603, Malaysia
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