Can Problem-Solving skills boost mood and memory in seniors with pain?

NCT ID NCT05081596

Recruiting now Symptom relief Sponsor: Weill Medical College of Cornell University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a program called PATH-Pain in 100 older adults (60+) who have mild cognitive impairment or early Alzheimer's, along with chronic pain and depression. The program teaches problem-solving and uses memory aids like checklists and a tablet app to help manage emotions and daily tasks. Researchers want to see if it improves thinking, mood, and pain-related disability compared to usual care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Problem Adaptation Therapy for Pain (PATH-Pain) – a behavioral intervention teaching problem-solving skills and using tools like checklists and a tablet app to manage emotions and daily challenges.
What this could lead to: If it works, this could provide a non-drug way to ease depression, pain, and cognitive difficulties in older adults with early memory loss.
What could go wrong: This is a small, early-stage study (100 participants) testing a behavioral approach, not a drug. Results may not apply to everyone, and the benefits might be modest or not last long.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease chronic pain syndrome Cognitive Dysfunction Depression depressive disorder Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COGNITIVE IMPAIRMENT DEPRESSION PAIN

Contacts and locations

Locations

Weill Cornell Medicine
RECRUITING

White Plains, New York, 10502, United States

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