Can Problem-Solving skills boost mood and memory in seniors with pain?

NCT ID NCT05081596

First seen Apr 23, 2026 · Last updated Jun 20, 2026 · Updated 10 times

Summary

This study tests a program called PATH-Pain in 100 older adults (60+) who have mild cognitive impairment or early Alzheimer's, along with chronic pain and depression. The program teaches problem-solving and uses memory aids like checklists and a tablet app to help manage emotions and daily tasks. Researchers want to see if it improves thinking, mood, and pain-related disability compared to usual care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Weill Cornell Medicine

    RECRUITING

    White Plains, New York, 10502, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Problem Adaptation Therapy for Pain (PATH-Pain) – a behavioral intervention teaching problem-solving skills and using tools like checklists and a tablet app to manage emotions and daily challenges.

What this could lead to

If it works, this could provide a non-drug way to ease depression, pain, and cognitive difficulties in older adults with early memory loss.

What could go wrong

This is a small, early-stage study (100 participants) testing a behavioral approach, not a drug. Results may not apply to everyone, and the benefits might be modest or not last long.

Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction Depression depressive disorder Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.