New social therapy aims to lift postpartum depression by fighting isolation

NCT ID NCT05585164

Recruiting now Symptom relief Sponsor: Weill Medical College of Cornell University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new type of talk therapy called Engage & Connect for mothers with postpartum depression. The therapy focuses on helping moms plan and do rewarding social activities to reduce feelings of isolation. Sixty participants will receive either this new therapy or a standard education session, both delivered remotely over 9 weeks. Researchers will measure changes in depression severity and social engagement.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Engage & Connect psychotherapy (behavioral intervention)
What this could lead to: If it works, this could offer a new, non-drug treatment option for postpartum depression that helps new mothers feel less isolated.
What could go wrong: This is a small, early-stage trial with only 60 participants, so results may not apply to everyone. The therapy is compared to another talk therapy, so the difference may be small.

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Conditions

The condition(s) this trial relates to.

postpartum depression

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTPARTUM DEPRESSION

Contacts and locations

Locations

Weill Cornell Medicine
RECRUITING

New York, New York, 10022, United States

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Other studies related to the condition(s) this trial covers.