Cure My Disease

Don't miss your cure!

 Log in / Sign up

Treating Mom's depression may help Baby's brain

NCT ID NCT05269732

Disease control Sponsor: McMaster University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time

Summary

This study looks at whether online group cognitive behavioural therapy (CBT) for mothers with postpartum depression can improve their baby's ability to regulate emotions. The trial involves 172 mothers and their infants (4-12 months old) in Ontario. Mothers receive either CBT plus usual care or usual care alone. Researchers measure infant temperament, brain activity, and mother-infant bonding to see if treating depression helps the baby.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
group cognitive behavioural therapy (CBT) delivered online
What this could lead to
If it works, this could show that treating a mother's postpartum depression helps her baby regulate emotions better, potentially improving long-term development.
What could go wrong
This is a relatively small study, and the benefits for infants may be modest or not last. The results depend on mothers completing the therapy and may not apply to all families.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 172 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2022

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 99 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * women 18 years of age or older * understand and speak English (so that they can participate in the CBT group and complete study measures) * live in Ontario (the primary WHCC catchment area) * have an EPDS score of 10 or more * meets diagnostic criteria for comorbid psychiatric conditions. * Infants must be between 4-12 months old at enrollment. Exclusion Criteria: * bipolar disorder * a current psychotic disorder * substance or alcohol use disorder * antisocial or borderline personality disorder.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Postpartum depression are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

postpartum depression

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postpartum depression

Contacts and locations

Locations

  • McMaster University

    Hamilton, Ontario, L8S 4L8, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.