Vitamin B6 could be a simple shield against postpartum depression

NCT ID NCT06445933

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This study investigates whether taking vitamin B6 supplements during late pregnancy and after childbirth can help prevent depression. Pregnant women without a history of mental health conditions take either vitamin B6 or a placebo from around 24-28 weeks of pregnancy until six weeks after giving birth. The trial also explores whether a wearable heart monitor can provide a more objective way to screen for depression than standard questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Vitamin B6
What this could lead to
If it works, this could offer a simple, low-cost way to help prevent perinatal depression and improve mental health screening during pregnancy.
What could go wrong
This is a relatively small study, and vitamin B6 may not significantly reduce depression risk. Results may not apply to all pregnant women.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Taiwan University Hospital

    RECRUITING

    Taipei, Taiwan

    Contact Phone: •••-•••-••••

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