National Taiwan University Hospital

This study is testing a new plan to help people safely stop a long-term osteoporosis drug called denosumab (Prolia). When this drug is stopped suddenly, bones can weaken quickly. Researchers want to see if giving a half-dose of the drug for a short time, along with a different bo…

This study is testing whether adding a wearable fitness tracker and an AI-powered smartphone app to a standard diet and exercise program helps obese adults lose more weight and improve their health. About 120 participants will follow a 6-month personalized program, with some usin…

This study is testing whether adding a second antibiotic (doxycycline) to the standard syphilis treatment works better for people living with HIV. Researchers will compare the standard single-shot penicillin treatment against the same shot plus a week of doxycycline pills. They'r…

This study is testing whether preserved tissue from a donor's aorta (the body's main artery) can be used as a patch to repair serious damage or defects in the windpipe (trachea) or bronchial tubes. It will involve 10 patients with severe airway problems from birth defects, injuri…

This study is testing if a drug called cilostazol can help the body clear a blood clot faster after a type of stroke called an intracerebral hemorrhage (brain bleed). Researchers will enroll 100 patients and give half of them cilostazol for two weeks along with standard care, whi…

This study is testing whether a 12-week exercise program guided by a case manager and supported by a smartphone app can help people with heart failure. Researchers want to see if this approach improves patients' fitness, walking ability, and quality of life compared to standard c…

This study is testing whether a mobile app-based lifestyle program and continuous glucose monitoring can help women who had diabetes during pregnancy. The goal is to improve blood sugar control during and after pregnancy and reduce the risk of developing type 2 diabetes or heart …

This study aims to find out if a drug called valacyclovir works as well as the standard drug, valganciclovir, at preventing dangerous viral infections in people who have received a kidney transplant. Researchers want to see if valacyclovir causes fewer serious side effects, like …

This study is testing a specific way to remove medium-sized growths in the colon, called polyps, which can sometimes turn into cancer. Doctors want to see if using a 'cold snare'—a wire loop without heat—is a safe and effective way to completely remove these polyps. About 120 peo…

This study compares two medical tools used to widen a passage for a bile duct drainage tube. Doctors want to see if a mechanical dilator causes less bleeding than an electrocautery (heat-based) one. The trial will include 64 adults with blocked bile ducts who need this procedure …

This study is testing whether a class of drugs called SGLT2 inhibitors can help people with acute kidney disease. Researchers want to see if these medications, already used for chronic kidney problems, can safely reduce protein in urine and protect kidney function during this cri…

This study aims to find the best schedule for two bone-strengthening drugs (romosozumab and denosumab) for postmenopausal women with severe osteoporosis. Researchers will compare a new alternating 6-month cycle over two years against the standard one-year-each schedule. The goal …

This study is testing a new support program for people with osteoporosis or who have broken a bone. The program helps patients manage their bone-strengthening medications and learn about nutrition and fall prevention. Researchers will follow 200 patients for two years to see if t…

This study is testing whether a gentle, non-invasive brain stimulation technique can help improve vision in people with glaucoma. Researchers will use repetitive transcranial alternating current stimulation (rtACS) to try to activate damaged eye nerve cells. They will measure cha…

This study is testing if a combination of three drugs (epinephrine, vasopressin, and methylprednisolone) works better than the current standard single drug (epinephrine) for treating adults who suffer a sudden cardiac arrest outside the hospital. The goal is to get the heart beat…

This study is testing a new treatment plan for people with a type of advanced esophageal cancer. The goal is to see if using a combination of immunotherapy and chemotherapy, followed by radiation and chemotherapy, all before surgery, can better shrink or eliminate the tumor. Rese…

This study is testing if adding a precise, high-dose internal radiation treatment can help control cancer better for people with a specific type of advanced esophageal cancer. Participants have already received standard chemotherapy, external radiation, and an immunotherapy drug.…

This study is testing a two-part treatment for advanced liver cancer. Doctors deliver chemotherapy directly to the liver tumor and add a temporary blocking agent (lipiodol) to cut off its blood supply. The goal is to see if this combination is more effective at shrinking tumors a…

This study aims to find the best way to treat H. pylori stomach infections when the first treatment fails. It will compare a personalized approach, where doctors choose antibiotics based on lab tests of the specific bacteria, against a standard, one-size-fits-all antibiotic combi…

This study aims to find out if a high-flow nasal cannula is better than a standard face mask at helping chest trauma patients breathe without needing a tube placed down their throat. It will involve 100 adults who have suffered chest injuries and are struggling with low oxygen le…

This study is comparing two types of radiation therapy for advanced cervical cancer: proton therapy and traditional photon therapy. Researchers want to see if proton therapy causes less damage to important immune cells and leads to fewer side effects while still effectively contr…

This study is testing whether hydroxychloroquine, a drug used for malaria and arthritis, can help treat fatty liver disease with inflammation. 210 adults with confirmed fatty liver and elevated liver enzymes will take either the drug or a placebo pill daily for one year. Research…

This study is testing if inflating a tiny balloon at four points is better than two points during a procedure to open a blocked tear duct. The goal is to see which method better controls the watery eye condition. Researchers will measure how often participants need to dab their e…

This study is testing whether taking oral activated charcoal and probiotics can slow the progression of kidney disease in people with diabetes. Researchers believe these supplements may reduce body-wide inflammation and change gut bacteria, which could protect the kidneys. The tr…

This study is testing whether adding core muscle training to standard cardiac rehabilitation exercises helps people recover better from a heart attack or heart failure. It will compare three different exercise programs over eight weeks in 60 stable patients. The main goal is to s…

This study is testing whether a 12-week language training program can help maintain or improve brain health in healthy older adults. About 90 volunteers aged 65+ will join small weekly groups for reading, writing, and discussion activities designed to exercise their thinking. Res…

This study is testing a new support program for people who have survived a serious illness in the Intensive Care Unit (ICU). The program combines regular check-up visits at a special recovery clinic with remote support through a smartphone app. Researchers want to see if this int…

This study is testing if regularly using Systane COMPLETE lubricating eye drops for 1-2 months before cataract surgery can improve the eye's surface in people with dry eye. Researchers want to see if this leads to more accurate predictions for the lens implant needed, potentially…

This study is testing whether a nutritional supplement called glutamine can help patients maintain muscle mass and strength after stomach removal surgery for cancer. Researchers will compare glutamine to a placebo in 120 patients, measuring muscle changes on CT scans and tracking…

This study is testing a special training program that combines physical exercises with brain games. It aims to help people with thinking and movement problems after a stroke or from a rare condition called Moyamoya disease. Researchers will compare this combined training to stand…

This study is testing a special nursing program designed to prevent delirium, a serious state of confusion, in critically ill patients on breathing machines in the ICU. The program, called mHELP@ICU, focuses on keeping patients mentally engaged, physically active, and well-nouris…

This study is testing whether using two different bone-strengthening medications together works better than either one alone for treating osteoporosis in postmenopausal women. It will involve 90 women who have not recently taken other osteoporosis drugs. Researchers will measure …

This study is testing whether artificial intelligence (AI) can help doctors interpret ultrasound images more quickly and accurately. It focuses on two specific conditions: fluid around the heart (pericardial effusion) and a swollen kidney (hydronephrosis). The goal is to create A…

This study is testing a new AI system that uses video to measure how well people can open their jaw and move their shoulder. Researchers will compare the AI's measurements to standard tools in 20 healthy adults and 20 oral cancer patients. The goal is to see if this simple, video…

This study is testing a new blood test called Nu.Q to see if it can accurately tell whether lung nodules found on a CT scan are benign or cancerous. Researchers will enroll 500 adults in Taiwan who have a lung nodule that needs a biopsy or surgery. They will compare the blood tes…

This study is testing if a simple, non-invasive ultrasound of the throat can safely identify stroke patients at high risk for choking and pneumonia. Researchers will scan the vocal cords of 200 recent stroke patients and track who develops choking or lung infections over the next…

This study is testing a new type of ultrasound called shear wave elastography to see if it can help doctors quickly figure out if a patient's kidney problem is a new, sudden issue (acute) or a long-term condition (chronic). The test will be given to 800 adults in a hospital emerg…

This study is testing whether artificial intelligence (AI) software can help family doctors and geriatric specialists better screen for two common causes of vision loss: diabetic eye disease and age-related macular degeneration. About 4,300 adults with diabetes or over age 50 wil…

This study is testing a new, non-invasive vision screening tool for young children. It uses an eye-tracking device and artificial intelligence (AI) to measure how well a child can see, which is especially helpful for infants, toddlers, and children with special needs who can't do…

This study is testing a new technology-based exercise system designed to help older adults improve their balance and prevent falls. Researchers will use body-worn sensors and artificial intelligence to create personalized training games that adjust to each person's movement patte…

This study aims to find out which type of flu vaccine works better for older adults with chronic health problems. Researchers will compare a standard flu shot with a newer version that contains an extra ingredient (an adjuvant) designed to boost the immune response. They will tra…

This study aims to prevent stomach cancer in Indigenous communities in Taiwan, where rates are much higher than in non-Indigenous populations. Researchers will enroll 50,000 adults aged 20-60 to test if treating a common stomach bacteria called H. pylori can lower cancer risk. Th…

This study is testing if a small change to the Pap smear procedure can encourage more women to get regular screenings for cervical cancer. Researchers are adding a brief, painless step at the end of the test for some participants, hoping it improves their memory of the experience…

This study is testing if washing the skin with a special acne cleanser before shoulder surgery can help prevent bacterial contamination. Researchers will compare patients who use the acne wash to those who use regular soap. The goal is to see if this simple step can reduce the ri…

This study is testing a new virtual reality (VR) training program designed to help people with schizophrenia improve their job interview skills and problem-solving abilities. Researchers will recruit 40 participants to complete the VR training and measure changes in their intervi…

This study is testing if a new combination of therapies can help people recover movement and function after a stroke. Researchers are comparing a program that starts with mirror therapy and then uses augmented reality (AR) games to programs using just AR or standard occupational …

This study aims to find the best training approach to help people regain arm movement and sensation after a stroke. Researchers will compare three different training methods—combining sensation and movement training, movement training alone, and sensation training alone—in 153 pe…

This study is testing if taking an oral anti-anxiety pill (XANAX) before a second cataract surgery improves patient comfort. It will measure if the pill reduces anxiety, pain, and increases satisfaction during the procedure compared to not taking it. The research involves 250 pat…

This study checks if the benefits of a special AI-guided physical therapy program last over time for people recovering from oral cancer. It follows 65 patients for 9 months after their therapy ends to see if they keep better jaw and shoulder movement, less pain, and a better qual…

This study is testing a specific chin-tuck exercise to see if it can improve swallowing function, especially for people who have trouble swallowing after a stroke. Researchers will use ultrasound to see how the exercise changes throat muscles during swallowing. They will also che…

This study is testing how well a dental implant can restore chewing ability for people who have lost a specific back tooth (the second molar). Researchers will measure chewing efficiency using a special gum before and after patients receive a single-tooth implant. The goal is to …

This study is testing whether a temporary, minimally invasive spinal cord stimulator can help people with advanced Parkinson's disease walk more steadily. The device, placed near the spine, sends electrical pulses and is being tried to reduce episodes where patients suddenly feel…

This study is testing if patients having major surgery for pancreas or bile duct tumors can safely avoid having a nasogastric (stomach) tube placed before and during their operation. Researchers will compare patients who skip the tube entirely to those who have it removed right a…

This study is testing which order of robotic therapy works better to improve arm and hand function in people who have had a stroke. About 72 participants will complete an intensive 6-week program, with one group starting therapy at the shoulder and the other starting at the hand.…

This study is testing whether a non-invasive, focused ultrasound device can reduce hand tremor in people whose shaking doesn't improve with medication. It will involve 12 adults with Parkinson's disease tremor, essential tremor, or dystonic tremor. Researchers will use the NaviFU…

This study is testing whether a short, two-week program can help children with autism who also have trouble sleeping. The program combines supervised aerobic exercise for the child with sleep coaching for their parents. Researchers will measure if this approach improves the child…

This study is developing and testing a robot named E-MOTE to provide emotional support to women newly diagnosed with gynecologic cancer who are having surgery. The robot aims to help patients manage distress, depression, and physical symptoms to improve their quality of life. Res…

This study is testing a non-invasive brain stimulation therapy to help reduce depression in people with schizophrenia. Depression is common in schizophrenia and can increase suicide risk, but current antidepressants often don't work well enough. Researchers will use magnetic puls…

This study is testing if using Systane COMPLETE lubricating eye drops before and after cataract surgery can help people who also have dry eye. Researchers want to see if the drops lead to more accurate vision correction from the surgery and reduce dry eye discomfort during recove…

This study is testing a new therapy that combines two approaches to help people with somatic symptom disorder, a condition where mental distress causes significant physical symptoms. Sixty participants will be randomly assigned to either receive the new therapy right away or be p…

This study is testing a sleep education program for children with epilepsy, who often have trouble sleeping. About 150 children, aged 1.5 to 9 years old, will try a program that combines in-person and digital sleep tips. Researchers will measure sleep using a wrist-worn activity …

This study is testing new, custom-made smart insoles created with 3D printing for people with flat feet and foot pain. Researchers will give 30 participants these insoles and measure changes in their foot pressure, pain levels, and daily activities. The goal is to see if this new…

This study is testing whether AI-guided physical therapy can help oral cancer patients maintain better movement and quality of life during treatment. One hundred newly diagnosed patients will either use a smartphone app that guides their jaw, neck, and shoulder exercises or recei…

This study is testing if giving an anxiety pill (Xanax) before cataract surgery improves the patient's experience. Researchers will give 400 patients either the pill or a placebo (a dummy pill) before their routine surgery to see if it reduces their anxiety and pain during the pr…

This study tests whether providing a robotic pet companion can reduce anxiety in intensive care unit (ICU) patients who are trying to breathe without ventilator support. It involves 24 adult patients who have previously struggled with this process. The goal is to see if less anxi…

This study is testing whether a combination of non-invasive brain stimulation and a specific practice method can improve how quickly and well healthy young adults learn a new motor skill. Researchers will use a technique called repetitive transcranial magnetic stimulation (rTMS) …

This study aims to follow 2000 adults with metabolic syndrome or prediabetes over time to understand how these conditions progress. Researchers will collect health data to identify which factors most influence the development of serious complications like heart disease and diabet…

This research study aims to use a special ultrasound technique to better understand how ligaments, tendons, and muscles behave during sports, after injury, and during rehabilitation exercises. It will involve 80 participants, including baseball pitchers, people with ankle tendon …

This study aims to better understand different types of small vessel brain diseases, which can lead to stroke or dementia. Researchers will use brain scans and genetic testing on 500 participants to see if they can identify patterns that predict who might develop these serious pr…

This study aims to better understand a serious lung condition that can develop after a stem cell transplant. Researchers will follow 600 adult transplant patients in Taiwan over time, collecting health data to see how often this complication occurs and what factors might be linke…

This study aims to understand how hospital support services affect the stress and mental health of family caregivers. Researchers will survey 200 primary caregivers of hospitalized patients at a medical center in Taiwan using questionnaires. The goal is to gather information that…

This study aims to understand the two-way relationship between gestational diabetes and depression during and after pregnancy. It will follow 600 women to see if factors like social support, diet, and activity influence this connection. Some participants with gestational diabetes…

This study aims to look back at the results of patients who have already had robotic-assisted surgery for urological conditions. It will review the medical records of up to 5,000 adults to understand surgical success, cancer control, and functional recovery. The goal is to gather…

This study aims to understand why some patients have slow stomach emptying after pancreatic cancer surgery, a common problem that hurts recovery and delays follow-up treatments. Researchers will look back at the medical records of about 500 patients who had surgery between 2005 a…

This study is testing whether a new app with videos and games is better than traditional paper instructions for teaching people how to prepare for a colonoscopy. Researchers want to see if the app improves how well people clean their bowels and if they find the instructions more …

This study aims to learn if a new type of blood test can predict how recurrent or metastatic head and neck cancer will progress. Researchers will analyze blood samples from 30 patients to look for specific cancer cells and immune cells. The goal is to see if these findings can he…

This study aims to test and create better guidelines for emergency responders on when to stop CPR attempts for patients who suffer a cardiac arrest outside the hospital. It will involve reviewing data from 140,000 cases across Asia to see if rules developed in Western countries w…

This study aims to understand how different surgical techniques for pancreatic tumors affect patients' long-term health and quality of life. Researchers will analyze medical records from 3,500 patients who had pancreas surgery to see how surgery impacts digestion and blood sugar …

This study aims to understand what factors affect how long patients need to lie flat and have pressure applied after a tube used in heart procedures is removed from their leg artery. Researchers will observe 157 ICU patients to identify which patient characteristics or conditions…

This study aims to understand the connection between a mother's depression during and after pregnancy and how she feeds her baby. Researchers will follow 500 first-time mothers, asking them to complete surveys four times from pregnancy until their baby is six months old. The goal…

This study aims to understand how autism affects movement skills like balance and coordination in adults. Researchers will compare 200 adults with and without autism using movement tests and virtual reality training. The goal is to see if specialized training can improve motor fu…

This study looks back at the medical records of 6,000 adults who suffered a cardiac arrest outside the hospital and were revived in the emergency room. Researchers want to see if the speed and type of care given in the ER—like how quickly tests are done—affects whether patients s…

This study aims to understand how mental health, depression, and quality of life are connected in adults living with type 2 diabetes. Researchers will survey 500 patients at a Taiwan hospital clinic using standard questionnaires. The goal is to identify factors that affect well-b…

This study aims to find new markers in urine that can tell the difference between aggressive, life-threatening prostate cancer and less serious forms. Researchers will analyze urine samples from about 2,000 men undergoing prostate biopsies to build and test a prediction model. A …

This study is investigating whether giving people with Parkinson's disease more control over their practice can help them learn new movements better. Researchers will have participants learn a finger-tapping task on a computer, with one group choosing when they get feedback and a…

This study is testing which type of training works better for emergency room teams that handle adult cardiac arrest. It compares training done in the actual emergency room (in-situ) versus training done in a separate simulation lab (off-site). The goal is to see which method impr…

This study aims to gather information about patients with completely blocked heart arteries that have been closed for over 3 months. Researchers will observe 5000 adults in Taiwan to understand which treatment techniques work best and what outcomes patients experience. The goal i…

This study is creating and testing a new training program for doctors to learn a specific type of heart ultrasound used during cardiac arrest. The program uses simulation practice and artificial intelligence (AI) to assess the doctors' skills. Researchers aim to see if this train…

This study aims to follow 2000 adults with type 2 diabetes over a long period to better understand the disease. Researchers will track participants' diet, body composition, strength, and health to see how these factors relate to future complications like heart or kidney problems.…

This study aims to understand if a specific gene variation (ALDH2) is linked to how long patients survive after an esophageal cancer diagnosis. Researchers will analyze genetic information from 700 patients who have already been diagnosed with esophageal cancer. The goal is to se…

This study aims to find substances in urine that might predict how well prostate cancer treatments work and what side effects patients might experience. Researchers will collect urine samples from 360 men with prostate cancer before they start treatment. The goal is to develop fu…

This study aims to better understand how sensory experiences, like sensitivity to sound or touch, are connected to social challenges in autism, such as avoiding eye contact. Researchers will observe 480 people with and without autism across different ages, using questionnaires, e…