National Taiwan University Hospital

This study compares two seasonal flu vaccines—one with an extra ingredient to boost the immune response (adjuvanted) and one without—in 200 adults aged 65 and older who also have chronic medical conditions like diabetes or heart disease. The goal is to see which vaccine triggers …

This study tests whether giving a combination of immunotherapy and chemotherapy, followed by chemoradiation, before surgery can improve outcomes for people with locally advanced esophageal cancer. The goal is to shrink the tumor and reduce the chance of the cancer coming back. Ab…

This study tests whether adding a precise, high-dose internal radiation treatment (brachytherapy) after standard external radiation, chemotherapy, and the immunotherapy drug nivolumab can help prevent esophageal cancer from coming back. About 60 adults with advanced esophageal sq…

This study tests whether adding bismuth to a 14-day course of vonoprazan and amoxicillin works better than the two-drug combo alone for eradicating H. pylori, a bacteria that can cause stomach ulcers and cancer. About 990 adults who have not been treated before will participate. …

This study compares proton therapy to standard photon therapy for cervical cancer patients who need radiation to a large area. The goal is to see if proton therapy can prevent a severe drop in immune cells (lymphopenia) and reduce side effects. About 44 adults with advanced cervi…

This study tests whether the antibiotic rifabutin can improve treatment for people with lung infections caused by Mycobacterium abscessus that are resistant to the common antibiotic clarithromycin. About 60 adults with active lung disease will receive rifabutin as part of their t…

This study tests whether a step-down approach—using half-dose denosumab (Prolia) combined with zoledronic acid (Aclasta)—can better prevent bone loss in people who have been on denosumab for at least three years. The trial includes 44 postmenopausal women and men aged 50–85 with …

This study tests two different ways of giving osteoporosis drugs to postmenopausal women with very low bone density. One group gets a repeating 6-month cycle of two drugs for 2 years, while the other gets one drug for a year followed by another for a year. The goal is to see whic…

This study tests a mobile health program that helps women with gestational diabetes adopt healthier habits after pregnancy. The goal is to reduce their future risk of heart disease and diabetes. Researchers will track blood sugar, cholesterol, and baby outcomes in 120 participant…

This study tests whether a preserved donor aortic patch can safely repair holes or defects in the windpipe or breathing tubes. Ten people with severe airway problems from birth or injury will receive the patch. The main goal is to see if it helps them breathe better without major…

This study tests whether SGLT2 inhibitors, drugs already used for diabetes and chronic kidney disease, can help people with acute kidney disease (AKD) recover and avoid progressing to chronic kidney disease. About 264 adults with AKD, with or without diabetes, will receive either…

This study tests whether a wearable device and AI app can help obese adults lose more weight than standard diet and exercise alone. About 120 participants will follow a 6-month program with coaching and tracking. The goal is to see if technology boosts weight loss and improves he…

This study tests whether adding doxycycline to the standard penicillin shot works better for treating early syphilis in people with HIV. About 688 adults will be randomly assigned to get either penicillin alone or penicillin plus a 7-day course of doxycycline pills. The main goal…

This study tests whether cilostazol, a drug already used for stroke prevention, can help the brain clear blood clots faster after a bleeding stroke (intracerebral hemorrhage). About 100 adults will be randomly assigned to receive either cilostazol plus standard care or standard c…

This study tests whether taking activated bamboo charcoal and probiotics can reduce inflammation and slow the progression of chronic kidney disease in people with diabetes. About 300 participants with different stages of kidney disease will take these supplements for 6 or 12 mont…

This study tests whether hydroxychloroquine, a drug used for malaria and autoimmune conditions, can improve liver health in people with nonalcoholic steatohepatitis (NASH). About 210 adults will take either a low or high dose of the drug or a placebo daily for one year. The goal …

This study tests whether a treatment tailored to the specific antibiotic resistance of a person's H. pylori bacteria works better than standard guideline-recommended therapy for people whose first treatment failed. About 450 adults with persistent H. pylori infection will be rand…

This study looks at whether giving a combination of three drugs (epinephrine, vasopressin, and a steroid) to adults who suffer a sudden cardiac arrest outside the hospital can restart their heart better than the standard single drug (epinephrine). About 1,344 participants will be…

This study tests whether taking glutamine by mouth can help people with stomach cancer recover muscle mass and nutrition after having their stomach removed. About 120 adults who had stomach cancer surgery will take glutamine supplements, and researchers will measure changes in mu…

This study tests whether combining two osteoporosis drugs (romosozumab and denosumab) works better than either drug alone for postmenopausal women with weak bones. 90 women will receive one of three treatments for 6 months, and researchers will measure changes in bone density and…

This study tests a treatment for advanced liver cancer that delivers chemotherapy directly to the liver through a small tube, combined with a temporary blocking agent (lipiodol) to trap the drugs in the tumor. The goal is to shrink tumors while keeping the liver working well. Abo…

This study tests whether valacyclovir works as well as valganciclovir for preventing CMV and EBV infections in kidney transplant patients. Both drugs are used to stop these viruses from becoming active after transplant. Valacyclovir may have fewer side effects, especially less bo…

This study looks at whether using a 10% benzoyl peroxide acne cleanser on the skin before rotator cuff repair surgery can reduce harmful bacteria. About 150 adults scheduled for shoulder surgery will be randomly assigned to either use the acne wash or their usual soap. The goal i…

This study enrolls 200 adults aged 50 and older in a rural area who have had a hip or spine fracture or are on osteoporosis medication. It provides education, monitoring, and follow-up every 4 months for 2 years to help patients stick with their treatment and reduce fracture risk…

This study is testing a new blood test called Nu.Q to see if it can accurately tell whether a lung nodule is cancerous or not. Researchers will collect blood from 500 adults who have lung nodules found on CT scans and compare the blood test results with the final diagnosis from b…

This study tests a new, non-invasive eye-tracking system that uses artificial intelligence to check vision in young children, including those with special needs. The goal is to find vision problems early, even in kids who can't do standard eye tests. Researchers will compare the …

This study tests a special ultrasound technique called shear wave elastography to help doctors quickly tell if kidney disease is acute (new) or chronic (long-standing). The goal is to make diagnosis faster and safer for patients in the emergency room, avoiding the need for contra…

This study tests whether using an AI tool (VeriSee) during regular checkups can help find two common eye diseases—diabetic retinopathy and age-related macular degeneration—earlier than standard exams. About 4,300 adults with diabetes or aged 50+ will be randomly assigned to eithe…

This study aims to prevent gastric cancer in Aboriginal people living in remote areas of Taiwan, where rates are higher than in non-Indigenous populations. Researchers will test and treat up to 50,000 adults aged 20-60 for H. pylori infection, a major cause of stomach cancer. The…

This study is testing a new balance training system for older adults that uses wearable motion sensors and artificial intelligence. The system creates personalized exercise programs to improve walking stability and prevent falls. Researchers will enroll 120 adults aged 18 to 80 w…

This study is developing and testing a friendly AI robot called E-MOTE to provide emotional support to women who have just had surgery for gynecologic cancer. The robot will assess their distress and offer personalized psychological help. Researchers will measure whether it reduc…

This study looks at whether giving patients an anti-anxiety pill (Xanax) before cataract surgery can help them feel less pain and anxiety during the procedure. About 400 adults having cataract surgery will be randomly given either Xanax or a placebo. Researchers will measure thei…

This study looks at whether a short, two-week program combining aerobic exercise with a parent-led cognitive behavioral strategy can improve sleep and daily functioning in children with autism who also have sleep problems. About 120 children aged 3-11 will take part. The goal is …

This study tests whether a 12-week smartphone-assisted cardiac rehabilitation program, led by a case manager, can help heart failure patients exercise more and feel better compared to usual care. About 150 adults with stable heart failure will take part. The goal is to see if the…

This study tests whether a high flow nasal cannula (a device that delivers warm, moist oxygen through the nose) works better than a standard face mask for people with chest injuries who have low oxygen levels. About 100 participants will be randomly assigned to one of the two dev…

This study tests a new therapy that combines cognitive-behavioral therapy (CBT) with biofeedback to help people with somatic symptom disorder—a condition where emotional distress shows up as real physical symptoms. Sixty adults diagnosed by a psychiatrist will either receive the …

This study tests whether an AI-powered physiotherapy app can help oral cancer patients regain jaw movement, shoulder function, and overall physical ability after surgery, chemo, or radiation. One hundred adults aged 20-65 will be split into two groups: one using the AI app for 12…

This study tests a new swallowing exercise called direct chin-tuck against resistance (dCTAR) in 60 healthy adults and stroke patients with swallowing problems. The exercise involves tucking the chin while pushing against resistance, which may help open the throat more during swa…

This study tests whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can reduce depression in people with schizophrenia. About 180 adults with schizophrenia and depressive symptoms will receive either standard rTMS or a ne…

This study tests whether a non-invasive brain stimulation technique called rtACS can help people with glaucoma. The treatment aims to activate damaged cells in the eye and improve vision. Researchers will measure changes in visual field tests before and after treatment. The study…

This study looks at whether taking an oral anti-anxiety medication (Alprazolam) before cataract surgery can reduce pain, anxiety, and improve overall satisfaction. It involves 250 adults who are already scheduled for their second-eye cataract surgery. The goal is to find a safe, …

This study tests if applying a gel containing indomethacin to the hands before starting sorafenib can prevent or reduce hand-foot syndrome, a common and painful skin reaction. It involves 39 adults with advanced liver cancer who are about to begin sorafenib treatment. Participant…

This study tests a temporary spinal cord stimulation device to help people with advanced Parkinson's disease who experience freezing of gait—a sudden inability to move their feet. Researchers will place small electrodes near the spine to see if it improves walking and reduces fal…

This early study tests whether low-intensity focused ultrasound can safely reduce hand tremors in 12 people with Parkinson's disease, essential tremor, or dystonic tremor who haven't responded well to medication. Participants receive a single session of brain stimulation, and res…

This study tests a non-invasive technique called focused ultrasound to see if it can improve arm movement in people who recently had a stroke. About 50 participants will receive the ultrasound treatment, and researchers will check for side effects and measure changes in brain act…

This study tests whether completely avoiding a nasogastric tube (a tube through the nose into the stomach) after pancreatic surgery is as safe and effective as removing it soon after surgery. The goal is to reduce patient discomfort and complications. About 240 adults aged 20–75 …

This study tests whether a training program that combines both touch (somatosensory) and movement (motor) exercises can help people with chronic stroke improve arm function better than either type of training alone. Researchers will enroll 153 participants who have had a stroke a…

This study looks at whether starting with mirror therapy and then adding augmented reality (AR) can help people who have had a stroke improve arm movement and balance. The researchers will work with 75 adults who had a first stroke 3 months to 3 years ago. The goal is to see if t…

This study looks at whether using Systane COMPLETE eye drops regularly before cataract surgery can improve dry eye symptoms and help with surgical planning. About 150 adults aged 20-85 with dry eye who need cataract surgery will use the drops and be monitored. The goal is to see …

This study tests a nursing-led program called mHELP@ICU to reduce delirium (sudden confusion) in critically ill patients on breathing machines. About 266 adults will be randomly assigned to receive either the program or usual care. The program includes mental activities, physical…

This study tests whether a robotic pet companion can reduce anxiety and help ICU patients on ventilators succeed in their breathing trials. 24 adults who have already failed one breathing test will receive the robotic pet intervention. The goal is to see if it improves their beha…

This study compares two ways of using a robot to help people with chronic stroke improve arm movement. About 72 participants will receive 18 sessions of robotic therapy over 6 weeks, focusing either on the shoulder first or the hand first. Researchers will measure arm function, m…

This study looks at whether a method called cold snare polypectomy can safely remove medium-sized (10-20 mm) colon polyps without using heat. About 120 adults having a colonoscopy will take part. The goal is to see if the polyps can be fully removed and to track any bleeding or o…

This study looks at two methods to widen a blocked bile duct during a special scope procedure. The goal is to see if using a mechanical dilator causes less bleeding than the standard electrocautery tool. About 64 adults who cannot have the usual ERCP procedure will take part. The…

This study is testing a new job training program that uses virtual reality to help people with schizophrenia improve their job interview skills and manage symptoms. The program is for 40 adults aged 20 to 55 who are motivated to work. Researchers will measure changes in symptoms …

This study tests new 3D-printed smart insoles for people with foot pain from flat feet. Thirty participants will get custom insoles made from a 3D scan of their feet. The goal is to see if these insoles reduce pain, improve walking, and boost quality of life.

This study tests whether using four balloon inflation points during a tear-duct procedure works better than the usual two points to relieve constant tearing. About 50 adults with blocked tear ducts will be treated and followed for symptom improvement. The goal is to find a more e…

This study follows oral cancer patients who completed a previous rehabilitation trial. It compares AI-based physiotherapy to standard physiotherapy to see which better improves jaw movement, shoulder function, overall physical health, quality of life, and return to work. Research…

This study tests whether oxybutynin, a medication used for overactive bladder, can help men recover bladder control sooner after robotic prostate cancer surgery. About 135 men will receive either the drug or a placebo daily for up to 3 months. Researchers will track how many achi…

This study tests a new, gentle treatment called cold atmospheric plasma (CAP) for wounds where tubes enter the body in patients on life support. These wounds often heal slowly and get infected. The study will compare standard wound care alone to standard care plus CAP in 65 adult…

This study tests whether a non-invasive brain stimulation technique called rTMS can reduce physical discomfort and excessive worry about health in people with somatic symptom disorder. About 30 adults aged 20-70 will receive both real and sham (fake) stimulation in a random order…

This study looks at whether using Systane COMPLETE eye drops before and after cataract surgery can help people with dry eyes. Researchers will measure how the drops affect eye surface stability and vision measurements. The goal is to see if these drops can make surgery planning m…

This study tests a sleep improvement program for children with epilepsy, who often have worse sleep problems. The program combines clinic visits with technology support. Researchers will measure sleep quality and quantity using a wrist-worn device. The goal is to help both childr…

This study tests a new robot that helps people who had a stroke 6 months to 3 years ago improve their walking. The robot has a special mode that encourages patients to actively move their legs, rather than just being moved by the machine. 60 participants will receive 15 training …

This study looks at whether adding core muscle exercises (like Pilates) to standard cardiac rehab helps people recovering from heart attacks or heart failure. Sixty adults will be split into three groups: core training only, aerobic exercise only, or both combined. The goal is to…

This study looks at whether letting people with Parkinson's disease choose when they get feedback helps them learn new motor skills. 72 participants will practice a finger-pressing task, with one group having control over feedback and the other not. Researchers will measure accur…

This study enrolls 500 people with brain small vessel disease (CSVD) to see how genetics influence their condition. Participants get genetic testing for five key genes and are followed for at least two years. The goal is to track strokes and dementia, not to test a new treatment.

This study looks at why some ICU patients bleed longer after a tube is removed from an artery in the groin following heart procedures. Researchers will track 157 adults to find factors that affect how long it takes to stop bleeding and how long patients must lie flat. The goal is…

This study tests a new way to predict how well your lungs will work after lung cancer surgery. Doctors use a 3D CT scan to create a virtual model of your lungs and simulate the surgery beforehand. The goal is to improve safety and help plan recovery. About 60 adults with non-smal…

This study is looking for substances in urine that might help doctors predict how well prostate cancer treatments will work. Researchers will collect urine samples from 360 men with prostate cancer who are receiving standard treatments like surgery, radiation, chemotherapy, or ho…

This study follows 600 adults who have had a stem cell transplant to see how many develop a serious lung condition called bronchiolitis obliterans syndrome. Researchers will track symptoms and lung function over time without giving any new treatments. The goal is to better unders…

This study aims to understand how people with autism experience senses like touch, sound, and sight differently across their lives. Researchers will use brain scans and questionnaires to link these sensory differences to social challenges, such as avoiding eye contact or feeling …

This study looks at people who had part or all of their pancreas removed (pancreatectomy) to understand how the surgery affects their body's ability to control blood sugar and digest food. Researchers will review medical records from 3500 patients to see how different surgical me…

This study looks at whether a special blood test can help predict how advanced head and neck cancer will progress. Researchers will collect blood samples from 30 patients with recurrent or metastatic head and neck cancer. They will analyze cancer cells and immune cells in the blo…

This study looks at whether an ultrasound of the vocal cords can help predict choking or pneumonia risk in people who recently had a stroke. Researchers will check vocal cord movement with ultrasound and then follow 200 participants for one year to see who develops choking or lun…

This study looks at rules used by emergency workers to decide when to stop trying to restart a person's heart after a cardiac arrest outside a hospital. These rules were made in Western countries, and researchers want to see if they work well for people in Asia. They will study 1…

This study looks at how autism affects motor functions like muscle strength, balance, and coordination in adults aged 18 to 45. Researchers will also test whether a 6-week virtual reality training program can help improve these skills. The goal is to better understand the link be…

This study creates a training program using simulation and artificial intelligence to teach junior doctors how to use transesophageal echocardiography (TEE) during cardiac arrest. About 60 emergency physicians will learn and be tested on their skills. The goal is to improve how q…

This study is looking back at the medical records of 5,000 people who had robot-assisted urological surgery. The goal is to see how well the surgery worked for treating cancer and preserving normal body functions. It includes adults 18 and older who had this type of surgery.

This study tests whether 12 weeks of small-group reading and writing workshops can improve thinking skills in healthy adults aged 65 and older. Participants are randomly assigned to an active language group, a passive reading group, or a board game group. Researchers measure chan…

This study explores whether artificial intelligence (AI) can accurately interpret ultrasound images of the heart and kidneys. Researchers will develop and test AI models using images from 300 patients. The goal is to see if AI can help doctors quickly and correctly identify fluid…

This study tests a program called I-CARE that combines remote support through a smartphone app with in-person clinic visits for people who have been in the ICU. The goal is to see if this approach reduces unplanned hospital visits and helps patients regain physical and mental fun…

This study looks at whether a specific gene, ALDH2, which helps break down alcohol, is linked to how long people with esophageal cancer survive. Researchers will follow 700 patients for up to 150 months to track survival. The goal is to understand how genetic differences might in…

This study tests whether a smartphone app with animations and games helps people prepare better for a colonoscopy compared to standard written instructions. About 252 adults scheduled for a colonoscopy will be randomly assigned to one of two education methods. The goal is to see …

This study explores how depression during and after pregnancy influences how first-time mothers feed their babies. Researchers will follow 500 women from late pregnancy through 6 months after birth, using questionnaires to track mood, breastfeeding, and introduction of solid food…

This study will follow 2,000 adults with metabolic syndrome or prediabetes for many years. Researchers will track their health, nutrition, and physical function to learn how these conditions progress and lead to complications. The goal is to find key factors that affect long-term…

This study is testing whether an AI system can accurately measure jaw, neck, and shoulder movement in people with and without oral cancer. Researchers will compare the AI's measurements to standard methods. The goal is to develop a simpler way to track movement problems caused by…

This study is observing 500 adults with type 2 diabetes to understand how their mental well-being, depression, and quality of life are related. Participants will fill out questionnaires about their feelings and daily life. The goal is to find patterns that can help doctors offer …

This study looks at 5,000 people in Taiwan who have a completely blocked heart artery for at least 3 months. Researchers want to learn what factors help doctors successfully open these blockages and how patients fare afterward. The goal is to gather information, not to test a new…

This study tests whether adding a brief, painless step at the end of a Pap smear can make the experience less unpleasant and encourage women to return for future screenings. About 248 women aged 25 and older will be randomly assigned to receive either the standard Pap test or the…

This study looks at whether training that mixes mental tasks with physical exercises can improve thinking and movement in people with stroke or Moyamoya disease. Researchers will measure brain activity during these tasks using a special light-based scanner. The goal is to underst…

This study looks back at the medical records of about 3500 adults who had pancreatic surgery to find out why some develop delayed gastric emptying (stomach not emptying properly). The goal is to identify risk factors and improve care. No new treatments are tested; instead, resear…

This study looks at how gestational diabetes and depression influence each other during pregnancy and after childbirth. Researchers will follow 600 women, some with gestational diabetes, to track changes in mood, social support, and health habits. A subgroup will receive health e…

This study follows 2,000 adults with type 2 diabetes to see how their diet, body composition, and grip strength change over time. Participants will have basic health checks like height, weight, and strength tests. The goal is to learn more about the disease, not to test a new tre…

This study looks at whether a type of brain stimulation called rTMS, combined with letting people choose when to get feedback during practice, can improve how well they learn a motor task. Researchers will test 72 healthy adults aged 18-35 over 7 days. The goal is to understand h…

This study aims to better understand serious prostate cancer by analyzing urine samples from 2,000 men. Researchers hope to find new markers that can help detect life-threatening prostate cancer more accurately and reduce unnecessary treatment for harmless forms. Participants inc…

This study checks if an AI-based system can accurately measure how well people can move their jaw, neck, and shoulders. Twenty healthy adults will perform simple movements while the AI and two human raters take measurements. The goal is to see if the AI is as reliable as traditio…

This study looks at how well people can chew after getting a single dental implant to replace a lost second molar. Researchers will give participants a piece of chewing gum to measure their chewing efficiency. The goal is to understand how implant-supported fixed dentures improve…

This study looks at how care in the emergency department (ED) after a cardiac arrest affects short-term survival. Researchers will review records from 6,000 adults who had a cardiac arrest outside the hospital and were revived in the ED. They want to see if the timing of treatmen…

This study uses a special ultrasound technique to measure how ligaments, tendons, and muscles stretch and move in different groups of people. Researchers will study baseball pitchers, people with ankle tendon problems, and patients recovering from ACL knee surgery. The goal is to…

This study looks at two ways to train emergency room teams for adult cardiac arrest: training in the actual emergency room (in-situ) versus training in a separate simulation center (off-site). About 100 healthcare workers from two hospital campuses will take part. The goal is to …

This study aims to create and test a simple scale that caregivers can use to detect common eye disorders in adults with intellectual disability. Currently, no such tool exists, leading to delayed diagnosis. Researchers will work with 1,400 caregivers and adults with intellectual …