National Taiwan University Hospital

This study investigates whether regular blood tests can detect liver cancer earlier in people with type 2 diabetes who also have significant liver scarring. Participants are randomly assigned to either a surveillance group receiving specialized blood tests every six months or a s…

This trial tests whether tirzepatide, a drug used for diabetes and weight loss, can reduce the return of atrial fibrillation (AFib) after a heart procedure called catheter ablation. Overweight or obese adults with persistent AFib will receive either tirzepatide injections plus st…

This study follows 30 adults with paroxysmal atrial fibrillation (PAF) who have or will get a special pacemaker. The pacemaker can detect irregular heartbeats early and send a painless pacing pulse to stop them. It also sends data to doctors remotely. Researchers will check how w…

This study tests a non-invasive device called the Hypotension Prediction Index (HPI) in 60 elderly patients (ages 65-90) undergoing shoulder surgery in a beach chair position. The device predicts when blood pressure might drop dangerously low, allowing doctors to intervene early.…

This study tests a new combination of drugs (PLD, cyclophosphamide, trastuzumab, and pertuzumab) for people with HER2-positive early breast cancer who still have cancer after initial treatment. The goal is to see if this combo can increase the rate of complete remission before su…

This phase II trial tests three radiation approaches for people with six or more brain metastases from solid tumors. One group gets focused high-dose radiation (SRS), while the other two get whole-brain radiation with memory-sparing techniques plus a drug called memantine. The go…

This study tests whether a telemedicine program using a smartphone app and a smartwatch can help people with advanced liver disease (decompensated cirrhosis) avoid hospital stays and emergency room visits. About 120 adults with this condition will either receive standard care or …

This study compares two bone-strengthening drugs, ibandronate and zoledronic acid, given after stopping denosumab in postmenopausal women with osteoporosis. The goal is to see which drug better maintains bone density and prevents fractures. About 52 women aged 50-85 who took deno…

This study tests a program that uses artificial intelligence to guide exercise and continuous glucose monitors to help people with both knee osteoarthritis and obesity. The goal is to see if it can improve blood sugar control, reduce knee pain, and lower the need for knee replace…

This early-phase study tests a new approach for people with pancreatic cancer that has spread to the liver and who have already tried standard chemotherapy. The treatment combines standard chemotherapy drugs with a special ultrasound technique that uses tiny bubbles to help deliv…

This study tests a custom 3D-printed implant designed to rebuild the spine after removing a tumor. The implant is less rigid than traditional ones, which may help bone grow better and reduce sinking. Researchers will follow 18 adults for safety and how well the implant fuses with…

This study tests whether giving two hormones (HCG and GnRH agonist) together before transferring a frozen embryo can improve implantation rates. About 170 women aged 24-45 undergoing modified natural cycle frozen embryo transfer will be randomly assigned to receive either the sta…

This small study will test whether empagliflozin, a drug typically used for diabetes, can improve abnormal heart patterns in people with Brugada syndrome. Ten participants will take the drug daily for three months, and researchers will monitor their heart rhythms and any side eff…

This study compares a new 3D colonoscopy with the standard 2D version to see which more accurately identifies polyps that could become colorectal cancer. About 600 adults undergoing colonoscopy will have their polyps examined with both methods, and the results will be checked aga…

This study tests whether using artificial intelligence (AI) along with a smartwatch and a heart monitor patch can find a hidden heart rhythm problem called atrial fibrillation (AF) in people who have had a stroke. AF can cause strokes, but it often comes and goes without symptoms…

This study tests an artificial intelligence (AI) system that reads chest X-rays in real time to help doctors quickly find misplaced breathing or feeding tubes and lung collapse (pneumothorax). The trial will involve about 10,900 patients in emergency and intensive care units. The…

This study will compare two enhanced flu vaccines—one with an adjuvant (MF59) and one with a higher dose—in 350 adults living with HIV. The goal is to see which vaccine triggers a stronger immune response. Participants will receive one shot and have their antibody levels checked …

This study tests whether colchicine, a drug usually used for gout, can prevent atrial fibrillation (a type of irregular heartbeat) after coronary artery bypass surgery. About 400 adults scheduled for elective bypass will receive either colchicine or a placebo starting 3 days befo…

This study compares two ways to prevent colon cancer in people who have had multiple advanced polyps removed. One group gets a standard colonoscopy after three years, while the other group does a simple stool test every year for two years, and only gets a colonoscopy if the test …

This study tests a special air mattress that automatically turns ICU patients from side to side to prevent painful bedsores. Researchers will compare it to standard foam mattresses with manual turning by nurses. The goal is to see if the automatic mattress reduces nursing workloa…

This study tests whether a special light-emitting patch can reduce pain after urological surgery. 300 adults having kidney or adrenal gland surgery will receive either an active patch, an enhanced version, or a placebo patch. The main goal is to see if the patch lowers pain score…

This study tests whether an artificial intelligence-based dietary care app can reduce distress from bowel changes and improve quality of life in rectal cancer patients who have had anal-preserving surgery. One hundred participants will be randomly assigned to either standard diet…

This study tests whether an AI-powered physiotherapy system can help oral cancer patients improve mouth, neck, and shoulder movement after surgery or radiation. Fifteen participants will use the system for 4 to 6 weeks, doing daily exercises prescribed by the AI. The goal is to s…

This study tests whether combining a virtual reality forest experience with mindfulness practice can help reduce anxiety and depression in pregnant women. One hundred women between 20 and 24 weeks of pregnancy will either use VR forest sessions plus mindfulness or standard mindfu…

This study tests a nurse-led program for insomnia that also uses a health education chatbot. 80 adults with sleep problems will either get the program plus chatbot or just track their sleep. The goal is to see if the chatbot-assisted approach improves sleep, anxiety, depression, …

This study tests whether adding high-intensity pulsed electromagnetic field (HI-PEMF) therapy to standard exercise can reduce pain and improve daily function in people who have had a total hip replacement. Forty adults who had hip replacement due to osteoarthritis will receive ei…

This study tests whether extracorporeal shockwave therapy (ESWT) can reduce pain and improve daily function in people with peripheral neuropathy who also have plantar fasciitis (heel pain). About 114 adults will receive either real or sham shockwave treatment. The goal is to see …

This study tests a LINE chatbot that gives visual, interactive tips to help lung cancer patients handle side effects from their targeted therapy. About 178 adults with advanced lung cancer will either get usual care or also access the chatbot. The goal is to see if the chatbot bo…

This study tests whether giving lidocaine through an IV can reduce diaphragm twitching and coughing during a procedure called pulse field ablation for atrial fibrillation. Sixty adults with AFib will be randomly assigned to receive lidocaine or a placebo (saline). The goal is to …

This study tests a personalized brain stimulation technique called IAF-rTMS to help people recover movement after a stroke. Thirty-four adults who had a first ischemic stroke will receive either real or sham stimulation for two weeks each, in a crossover design. Researchers will …

This study tests whether a home exercise program delivered through a smartphone app can improve hand strength, muscle endurance, and emotional well-being in 60 adults scheduled for lung nodule surgery. Participants will do aerobic, resistance, and breathing exercises for at least…

This study tests a device called histotripsy, which uses focused ultrasound to break up tumors without cutting the skin. It is for people with abdominal tumors that cannot be surgically removed and are causing symptoms like pain. The goal is to see if the treatment improves quali…

This study compares immersive virtual reality (VR) training to traditional classroom lectures for teaching nurses how to care for stomas—surgical openings on the body. About 100 nurses will be randomly assigned to either two VR sessions or one classroom session. Researchers will …

This study explores whether nurse practitioners can effectively teach each other how to use bedside ultrasound to assess fluid status in patients. Sixty nurse practitioners or trainees will take part in a peer-led training program that includes online lectures and hands-on practi…

This study will test an artificial intelligence system that analyzes smartphone photos of hard-to-heal wounds to see if they are getting better, staying the same, or getting worse. Researchers will enroll 1,000 people with wounds that have not healed for over a month. The goal is…

This study will collect data from 10,000 people undergoing upper endoscopy to build an AI model that predicts the risk of developing stomach or esophageal cancer. Researchers will combine information from endoscopy images, tissue samples, genetics, and gut bacteria. Participants …

This study aims to establish normal swallowing measurements in 80 healthy Chinese adults using advanced imaging and pressure tests. As Taiwan's population ages, swallowing problems become more common, but there is little data on what is normal for Chinese people. The results will…

This study tests whether a special headset (extended reality) can help surgeons plan the removal of cancer-affected lymph nodes in the neck for people with lung cancer. Ten patients will have their PET and CT scans combined into a 3D model that the surgeon views just before surge…

This observational study will enroll 300 people with suspected lung lesions to see if 3D ultrasound can measure them as accurately as CT scans. Participants will undergo both ultrasound and CT imaging, and researchers will compare the results. If the 3D ultrasound works well, it …

This study is testing a new, non-invasive way to collect and analyze skin oil (sebum) using a simple adhesive patch called Sebutape. Researchers will recruit 200 people, including healthy volunteers and patients with acne, eczema, psoriasis, or seborrheic dermatitis. The goal is …

This study looks at whether a specially designed decision aid can help Taiwanese women who are thinking about freezing their eggs. The goal is to see if the tool improves their knowledge, reduces worry and regret, and helps them make a choice that fits their values. About 120 wom…

This study aims to improve how doctors predict and monitor thyroid cancer by combining genetic testing of tumors with protein analysis from urine samples. Researchers will follow 100 newly diagnosed thyroid cancer patients to see if these markers can detect early signs of recurre…

This study will ask about 1,000 nurses and nurse practitioners in Taiwan about their use of point-of-care ultrasound (a small ultrasound device used at the bedside). The goal is to learn how much they know about it, how often they use it, and what helps or gets in the way. The re…

This study tests whether extended reality (XR) can help doctors more accurately locate small lung nodules during CT scans. About 30 adults scheduled for lung nodule surgery will participate. The goal is to see if XR guidance improves precision and reduces complications.

This study will test whether a device called the Hypotension Prediction Index (HPI) can help doctors keep blood pressure stable during oral cancer surgery. About 100 adults having oral cancer surgery with flap reconstruction will take part. Half of the surgeries will use the HPI …

This study will measure tongue strength and biting force in 40 mouth cancer patients who use a special plate called an obturator to help them swallow. Researchers want to see how these measurements relate to what patients eat each day. The goal is to better understand how to impr…

This study looks at why some people have higher levels of TMAO—a chemical linked to heart disease—after eating red meat. Researchers will test if a specific gut bacteria gene (gbu) can predict TMAO levels. 65 healthy adults will eat a large amount of beef, and their blood and sto…

This observational study will check 60 healthcare workers for early signs of heart stiffness (diastolic dysfunction) and compare those who work night shifts to those who don't. Participants will fill out questionnaires and get an ultrasound of their heart. The goal is to see if s…

This study will follow 100 people who have had their stomach removed (gastrectomy) to see how their muscles change over time. Researchers will measure muscle thickness in the arms and legs to understand the pattern of muscle loss and how nutrition plays a role. The goal is to gat…

This study aims to find out how much tooth-replacement material is removed with each grinding stroke when adjusting a zirconia crown. Researchers will have 120 participants—dental students, interns, and experienced clinicians—grind standardized zirconia blocks and measure the mat…

This study is testing a new, non-invasive wearable device that tracks swallowing muscle activity. Researchers will enroll 20 healthy adults and 20 people with swallowing difficulties (dysphagia). The goal is to see if the device can accurately measure swallowing, which could lead…

This study aims to develop and test a remote training program for point-of-care ultrasound (PoCUS) tailored to hospital-at-home care. One hundred medical residents will be randomly assigned to either a new curriculum using peer training with remote supervision and simulation, or …

This study tests a smart stethoscope that continuously listens to breath sounds during anesthesia. The goal is to see if it can detect breathing problems like airway blockage or pauses in breathing before oxygen levels drop. Researchers will monitor 60 adults having breast surger…

This study looks at whether having an orgasm within 36 hours before prostate cancer surgery makes the seminal vesicles smaller and easier for the surgeon to remove. About 40 men will be randomly assigned to either ejaculate or abstain for at least 72 hours before their operation.…

This study compares two methods—mixed reality goggles and ultrasound—to help surgeons mark exactly where ribs are broken before surgery. About 30 adults with three or more broken ribs will take part. The goal is to see which method is more accurate and faster.

This study looks at whether getting a CT scan sooner after a person's heart stops outside the hospital and is revived can help them live longer. Researchers will review records from 5,000 adults treated at six hospitals in Taiwan. The goal is to find the best timing for CT scans …

This study will use ultrasound to measure changes in a shoulder muscle (upper trapezius) in 10 oral cancer patients who had neck surgery and physical therapy. The goal is to see if ultrasound can track muscle recovery and relate it to how well patients can move their arm. It is a…