National Taiwan University Hospital

This study looks at whether the PCV13 pneumonia vaccine is safe and helps prevent serious infections in people with multiple myeloma. About 100 participants will receive either one or two doses of the vaccine. Researchers will check how well the immune system responds and track s…

This study looks at whether heart failure patients can get the same benefits from doing spot-jogging at home as they would from going to a clinic for rehab. About 40 adults with heart failure will be assigned to either a home program with adjustable jogging intensity or a standar…

This study tests a new device that uses electrical pulses to destroy liver tumors located dangerously close to major blood vessels, where standard heat-based ablation often fails. Twenty adults with liver cancer who cannot have surgery will receive this treatment under general an…

This study tests whether a nurse practitioner-led team can help adults with multiple chronic illnesses get the right medications and reduce hospital readmissions. About 178 hospitalized adults with conditions like heart failure, diabetes, or kidney disease will be randomly assign…

This study tests whether a patch made from a donor's aorta (the large blood vessel from the heart) can safely repair damaged or narrowed windpipes in 5 children. The children in this study cannot have standard surgery. The main goal is to see if they survive 90 days after the ope…

This study tests whether a surgery called lymphovenous bypass can help people with diabetic peripheral neuropathy. The surgery aims to drain high-pressure lymph fluid into veins, which may reduce nerve pain, improve foot ulcers, and slow nerve damage. Researchers will enroll 60 a…

This early-phase trial tests whether lab-grown corneal cells, injected into the eye, can repair the inner layer of the cornea and improve vision. It includes 12 adults with severe corneal swelling and vision loss. The goal is to see if the treatment is safe and can restore enough…

This study tests whether a new AI tool (HPI) or simply raising the blood pressure alarm to 73 mmHg works better to prevent dangerously low blood pressure during surgery. About 100 adults having long surgeries will take part. The goal is to see which method keeps blood pressure mo…

This early study tests whether MRI-guided focused ultrasound can safely reduce symptoms in adults with severe obsessive-compulsive disorder (OCD) that hasn't improved with standard treatments. Ten participants will receive the ultrasound procedure and complete brain scans and sym…

This study looks at 300 adults in Asia who had a heart ablation for atrial fibrillation. It compares giving the blood thinner heparin as a steady drip versus as occasional shots. The goal is to see which method keeps blood clotting time in the ideal range (250-350 seconds) to red…

This study tests whether a natural vaginal gel (CH2) can help women with mild cervical cell changes (CIN1) and high-risk HPV clear the infection faster than a placebo. About 50 women will use the gel or a placebo for several months, with regular Pap smears and HPV tests to track …

This study is for people with chronic hepatitis B who stopped their antiviral medication, then had a dangerous flare-up of the virus. It tests if switching to a newer drug called tenofovir alafenamide (TAF) is effective at getting the virus back under control. The goal is to see …

This study looks at 50 people with partially blocked heart arteries to see if a new measurement method (NTG-Pd/Pa) works better than the standard saline method for diagnosing blockages. Participants will have both tests along with the usual FFR test. The goal is to find which met…

This study tests two non-invasive methods—high-resolution oral imaging and a gentle cell-collection technique—to screen for oral cancer. Researchers want to see if these methods can find suspicious spots as well as or better than standard visual exams and biopsies. The study incl…

This study looks at whether proteins found in urine can help doctors diagnose follicular thyroid cancer before surgery. Currently, the only way to confirm this cancer is by removing the thyroid and checking it under a microscope. Researchers are testing urine samples from 50 peop…

This study tests whether a new DNA test (mNGS) can help doctors identify the bacteria or virus causing pneumonia faster than standard methods. About 114 ICU patients on breathing machines will be randomly assigned to get either the new test or usual care. The goal is to see if fa…

This study tests whether personalized screening—using stool tests, blood tests, and risk scores—can better prevent stomach and colon cancer in adults aged 50-75. Researchers will enroll 40,000 healthy participants and track them over time. The goal is to find the most effective w…

This study tests if a newer, deeper form of non-invasive brain stimulation can reduce depression symptoms more than the standard method. About 90 adults with major depression who haven't gotten better with medication will receive daily sessions for four weeks. Researchers will me…

This study tests two non-invasive devices that stimulate the vagus nerve (one on the neck, one on the ear) to see which better reduces physical discomfort and health-related anxiety in people with Somatic Symptom Disorder. About 60 adults will try both devices in random order, ea…

This study looks at whether spending time in sunlight can improve sleep for people with Alzheimer's disease. Sixty participants with mild Alzheimer's and sleep issues will receive sunlight therapy and track their sleep for 14 days. The goal is to see if this simple, drug-free app…

This study looks at two ways to help older adults who are having trouble moving around and doing daily tasks. One approach, called reablement, focuses on personalized, meaningful activities to build skills and confidence. The other uses standard exercise routines. Researchers wil…

This study looks at whether adding one non-invasive biofeedback session to regular Kegel exercises can improve bowel function, reduce emotional distress, and boost quality of life in people who have had rectal cancer surgery. About 66 participants will either do Kegel exercises a…

This study explores whether a type of visual training called perceptual learning can improve vision in children aged 6 to 10 with mild nearsightedness (low myopia). Thirty children will be split into a training group and a control group. The training group will use a digital syst…

This study looks at two ways to help people with advanced cancer who have a blockage in their stomach that prevents them from eating normally. One method uses a metal tube (stent) placed through a scope, and the other uses a newer scope-guided technique to create a new passage. T…

This study tests a non-invasive treatment called High-Intensity Focused Ultrasound (HIFU) for people with abdominal tumors that cannot be removed by surgery. The goal is to see if HIFU can safely relieve symptoms like pain and improve quality of life. About 38 adults with benign …

This study tests whether virtual reality (VR) can help caregivers of children with pneumonia learn chest percussion—a technique to loosen mucus in the lungs. Researchers will compare VR training to standard teaching methods to see if it improves skill accuracy and reduces caregiv…

This study looks at whether a special vacuum dressing (incisional negative pressure wound therapy) can reduce wound complications like infection or splitting open after thigh flap surgery. About 138 adults having head and neck reconstruction with a thigh flap will be randomly ass…

This study tests whether a high-protein nutritional drink can help cancer patients aged 40 and older maintain muscle strength and reduce fatigue during chemotherapy. Participants with early signs of muscle loss will take the drink three times daily for 8 weeks while doing simple …

This study tests whether ChatGPT can act as a job coach for adults with autism spectrum disorder (ASD). Thirty motivated adults aged 18-45 will use ChatGPT for one week to practice job applications, interviews, and workplace social skills. The goal is to see if the AI tool improv…

This study looks at whether a structured care plan can help people with a severe type of stroke (brain hemorrhage) start moving earlier and more safely in the hospital. About 198 patients will be included, and the goal is to improve their mobility and reduce long-term disability.…

This study looks at why some people have a bigger rise in TMAO (a heart disease risk marker) after eating red meat. Researchers will check if a specific gene in gut bacteria, called gbu, can predict TMAO levels. 230 healthy adults will take L-carnitine pills and provide blood, ur…

This study compares two methods for deciding when to remove a nasogastric (feeding) tube in adults who have trouble swallowing after an acute illness. One method uses an ultrasound to measure throat movement, and the other relies on a speech-language pathologist's clinical judgme…

This study looks at how end-stage kidney disease affects recovery after pancreatic surgery. Researchers will review medical records from 100 patients to see how kidney failure severity and dialysis use impact complications, hospital stay, and costs. The goal is to provide better …

This study looks at how ups and downs in blood sugar (glycemic variability) affect diabetes self-care, blood sugar control, emotional distress, fatigue, and quality of life in 260 adults who have both gastrointestinal cancer and diabetes after surgery. In the first phase, researc…

This study aimed to find blood markers that could help doctors better diagnose and treat atrial fibrillation, a common heart rhythm problem. Researchers planned to test samples from 266 patients to see if certain markers could predict disease burden or treatment success. However,…

This study looks at two different ways to perform a heart procedure called ablation for a condition called paroxysmal supraventricular tachycardia (PSVT), which causes a fast heart rate. The goal is to see which method works best without using any X-ray radiation. About 70 adults…

This study looks at people aged 45-74 who had a positive fecal immunochemical test (FIT) but a normal colonoscopy. Even with a clear colonoscopy, these individuals may still have a higher risk of colorectal cancer later. The trial compares two follow-up strategies after two years…

This study looks at whether a shared decision-making tool helps people aged 40-49 who have a close family member with colorectal cancer choose between two screening tests: colonoscopy or a stool test (FIT). About 2,286 participants will be randomly assigned to either use the tool…

This study looks at whether a new simulation-based curriculum helps junior doctors learn ultrasound-guided procedures like thoracocentesis and abdominal tapping. About 200 doctors who attend the training will take part. The goal is to improve patient safety and medical education …

This study looks at how medical students learn from virtual standardized patients (computer programs) compared to real human actors. About 60 medical students from National Taiwan University will try both methods and give feedback through surveys and interviews. The goal is to se…

This study looks at how hospital-integrated care services relate to the stress and burden felt by family caregivers of hospitalized patients. Researchers will survey 200 primary caregivers at a medical center in northern Taiwan using standard questionnaires. The goal is to find w…

This study tests whether using a special 3D ultrasound during CPR can help find the best spot on the chest to push, so blood flows better to the heart and brain. About 50 adults who have a cardiac arrest outside the hospital will take part. The goal is to measure how much blood t…

This study explores whether substances found in urine can help doctors track thyroid cancer after treatment. Researchers are measuring specific proteins in the urine of 103 patients who had their thyroid removed. The goal is to find a simple, non-invasive way to monitor the disea…

This study looks back at the medical records of 2,500 liver cancer patients treated at a major hospital in Taiwan between 2019 and 2024. Researchers want to see how well newer drugs (like Keytruda, Tecentriq, and Lenvatinib) work compared to older treatments. They will measure su…

This study is a nationwide registry in Taiwan that will follow 300 people who have or will receive a leadless pacemaker—a small device placed inside the heart to help control abnormal heart rhythms. The goal is to track how well the device works and any complications that may ari…

This study looks at how the brain works in adults with autism, depression, or both. Researchers will use brain scans and tests to measure brain activity and inflammation. The goal is to better understand these conditions, not to test a new treatment. About 160 adults aged 20-50 w…

This study looks at 350 people who survived a cardiac arrest outside the hospital. Researchers use an artificial intelligence program to analyze brain CT scans and medical records. The goal is to better predict how well patients will recover, helping doctors and families make mor…

This study examines how infective endocarditis, a serious heart infection, has changed in Taiwan from 2006 to 2022. Researchers will analyze health records from over 2,200 patients to spot trends and improve care. The goal is to understand the disease better, not to test a new tr…

This study follows 200 adults in Taiwan who have bronchiectasis, a lung condition that causes widening of the airways and leads to repeated infections. Researchers will track their other health problems, treatments, and how the disease changes over time. The goal is to learn more…

This study looked at CT scans from 2000 adults who had scans for other reasons, not because of appendix problems. The goal was to map where the appendix is usually located in the body. Knowing this can help doctors better diagnose appendix-related issues in the future.

This study looks at the vision care needs of children and adolescents with special needs, who are much more likely to have vision problems than other kids. Researchers will interview parents, teachers, and caregivers to find out what barriers these children face when trying to ge…

This study looks at whether a heart ultrasound (called TTE) can help prevent another stroke in people who have already had one. Researchers will follow 2000 stroke patients who received a TTE to see if the test results help doctors make better treatment choices and reduce the cha…

This study follows 500 adults with obesity who are trying to lose weight. Researchers collect information like body measurements, blood tests, and lifestyle habits to find out what helps people succeed. The goal is to create personalized weight loss plans based on each person's u…

This study aims to create a standardized point-of-care ultrasound (PoCUS) training course for nurse practitioners in Taiwan. About 150 nurse practitioners from different hospitals will take the course and be tested on their skills right after and again 3 months later. The goal is…

This study looks at whether a special recovery program (ERAS) helps children leave the hospital sooner after lung surgery. About 100 children having lung surgery at National Taiwan University Hospital will take part. The program includes steps to speed healing and reduce complica…