Urine test may spot hidden thyroid cancer, avoid unnecessary surgery

NCT ID NCT05463107

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether proteins found in urine can help doctors diagnose follicular thyroid cancer before surgery. Currently, this type of thyroid cancer can only be confirmed after removing the thyroid. Researchers will collect urine samples from 50 patients with thyroid nodules or known thyroid cancers to see if certain proteins can accurately predict cancer. If the approach works, it could spare many patients from unnecessary surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple urine test to diagnose follicular thyroid cancer without needing surgery.

What could go wrong

This is a small, early study with only 50 participants. The urine biomarkers may not prove accurate enough for routine use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

multinodular goiter nodular goiter thyroid cancer thyroid gland follicular carcinoma thyroid gland papillary carcinoma thyroid gland undifferentiated (anaplastic) carcinoma Thyroid Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Taiwan University Hospital

    Taipei, Taiwan