Hidden thyroid cancers may be more common in Graves' disease than thought

NCT ID NCT07059507

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This study looks at how often thyroid cancer is found by accident when people with Graves' disease have their thyroid gland removed. Researchers will track 280 adults having this surgery and examine the removed tissue carefully for any cancer, including tiny microcarcinomas. They will also check whether factors like age, sex, or thyroid nodules make cancer more likely. The goal is to better understand the true risk and help guide future treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Total thyroidectomy (surgical removal of the entire thyroid gland)
What this could lead to
If this study finds that incidental thyroid cancer is common in Graves' disease patients, it could lead to better surgical decision-making and closer examination of removed thyroid tissue.
What could go wrong
This is an observational study, not a treatment trial, so it won't change care directly. The findings may not apply to all patients, and the true cancer rate could vary widely.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Minia University Hospital

    RECRUITING

    Minya, Minya Governorate, 61519, Egypt

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