Lab-Grown eye cells injected to reverse corneal blindness

NCT ID NCT06726174

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests whether injecting cultured corneal endothelial cells into the eye can repair damaged corneas and improve vision. Twelve adults with corneal swelling and poor eyesight received a single injection of donor cells grown in a lab. The goal is to see if the cells can restore a healthy cell layer, reduce swelling, and improve sight.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cultured corneal endothelial cells

What this could lead to

If successful, this could offer a new treatment to restore vision in people with corneal endothelial dysfunction, potentially reducing the need for corneal transplants.

What could go wrong

This is a very early Phase 1 trial with only 12 participants, so safety and effectiveness are not yet proven. The cells may not engraft properly or could cause inflammation or increased eye pressure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CORNEAL ENDOTHELIAL CELL DYSFUNCTION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

corneal endothelial dystrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Taiwan University Hospital

    Taipei, 100225, Taiwan