Lab-Grown eye cells injected to reverse corneal blindness
NCT ID NCT06726174
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial tests whether injecting cultured corneal endothelial cells into the eye can repair damaged corneas and improve vision. Twelve adults with corneal swelling and poor eyesight received a single injection of donor cells grown in a lab. The goal is to see if the cells can restore a healthy cell layer, reduce swelling, and improve sight.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cultured corneal endothelial cells
- What this could lead to
- If successful, this could offer a new treatment to restore vision in people with corneal endothelial dysfunction, potentially reducing the need for corneal transplants.
- What could go wrong
- This is a very early Phase 1 trial with only 12 participants, so safety and effectiveness are not yet proven. The cells may not engraft properly or could cause inflammation or increased eye pressure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CORNEAL ENDOTHELIAL CELL DYSFUNCTION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
National Taiwan University Hospital
Taipei, 100225, Taiwan